Drug Resistance Current Events | Drug Resistance News | 11
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MRSA in hospital intensive care -- what's growing where?
Researchers are finding out which bugs grow in intensive care units to develop a novel sampling regime that would indicate the threat of MRSA and other superbugs in the environment, scientists heard today (Monday 31 March 2008) at the Society for General Microbiology's 162nd meeting being held this week at the Edinburgh International Conference... view more... (2008-03-31)
Structural mechanism of the E. coli drug efflux pump AcrB
In a new study published online in the open access journal PLoS Biology, Gaby Sennhauser, Marcus Gruetter, and colleagues use structural biology techniques to probe the molecular mechanisms of the major drug efflux pump in E. coli AcrB. view more (2006-12-27)
Variation in the same gene affects rate of parasite infection in both humans and baboons
Researchers at the Duke University Institute for Genome Sciences & Policy have found that variation in the same gene in humans and baboons produces the same kind of disease resistance. view more (2009-06-25)
Targeting leukemic stem cells by Bcl-2 inhibition
Researchers at The University of Texas M. D. Anderson Cancer Center have found, in laboratory studies, that the experimental drug ABT-737 which has shown promise in some cancers, can destroy acute myeloid leukemia (AML) blast, progenitor and even stem cells that are often resistant to standard chemotherapy treatment. view more (2006-11-20)
High level of antibiotic resistance in bacteria that cause food poisoning
More than 40% of bacteria found in chicken on sale in Switzerland is resistant to at least one antibiotic, says research published this week in BMC Public Health. The findings could have implications for treating food poisoning. The bacteria, Campylobacter, causes between 5 and 14 percent of all diarrhoeal illness worldwide. The most common... view more... (2003-12-04)
News from space for osteoporosis patients on earth: resistance is not futile
Results of a space experiment published online in The FASEB Journal have yielded a giant leap for science that could translate into an important step for mankind in the ongoing battle against osteoporosis. view more (2009-03-30)
A new therapeutic option for human hepatocyte cancer
p53-impaired tumors may be particularly suitable to parvovirus H-1-induced therapy. Although the p53 deficiency in tumors may induce resistance to chemotherapeutic agents, this will not affect the tumor cell susceptibility to H-1 PV-induced oncolytic infections. view more (2008-09-24)
Evolution and the workaround
Living things are resourceful, which is a comforting thought unless the living thing in question is a pathogen or a cancer cell. Noxious cells excel at developing drug resistance, outwitting immune systems, and evading cellular controls. view more (2006-12-11)
Modified mushrooms may yield human drugs
Mushrooms might serve as biofactories for the production of various beneficial human drugs, according to plant pathologists who have inserted new genes into mushrooms. view more (2007-06-25)
Brain study may lead to improved epilepsy treatments
Using a rodent model of epilepsy, researchers found one of the body's own neurotransmitters released during seizures, glutamate, turns on a signaling pathway in the brain that increases production of a protein that could reduce medication entry into the brain. view more (2008-04-15)
Drug addiction treatment sees drop in success rate
The proportion of drug users who completed treatment for drug addiction decreased between 1998 and 2002, although the overall number of drug users who entered treatment increased. view more (2006-08-11)
Evolution follows few of the possible paths to antibiotic resistance
Darwinian evolution follows very few of the available mutational pathways to attain fitter proteins, researchers at Harvard University have found in a study of a gene whose mutant form increases bacterial resistance to a widely prescribed antibiotic by a factor of roughly 100,000. view more (2006-04-12)
Bisphenol A linked to chemotherapy resistance
Exposure to bisphenol A (BPA) may reduce the effectiveness of chemotherapy treatments, say University of Cincinnati (UC) scientists. view more (2008-10-09)
Concern over uncontrolled use of HIV drugs
Uncontrolled use of antiretroviral drugs in developing countries could accelerate HIV resistance, warn researchers in this week’s BMJ. view more (2003-06-18)
New cause of critical illness hypeglycemia identified
The endocrinologic basis of pediatric critical illness hypergylcemia (CIH) differs depending on the disease processes. Researchers writing in BioMed Central's open access journal Critical Care describe how both peripheral insulin resistance and primary beta-cell dysfunction can cause CIH in children. view more (2009-02-26)
Doctors call for change in how non-active TB in immigrant children treated
New guidelines proposed in the March 2009 issue of the journal Pediatrics by researchers from the Indiana University School of Medicine and Riley Hospital for Children may have a major impact on how U.S. pediatricians and family physicians treat non-active tuberculosis (TB) in children who are immigrants, internationally adopted or refugees. view more (2009-03-03)
Not all 'drug-related deaths' are 'drug-related'
UK estimates of 'drug-related deaths' (DRDs) include mortalities of drug abusers and non-drug abusers. So these figures may not be the best way of monitoring the performance of Drug and Alcohol Action Teams. view more (2007-08-09)
Female choice benefits mothers more than offspring
The great diversity of male sexual traits, ranging from peacock's elaborate train to formidable genitalia of male seed beetles, is the result of female choice. view more (2009-10-23)
Ireland Cancer Center researchers advance lung cancer treatment
Researchers at the Ireland Cancer Center of University Hospitals Case Medical Center have developed methods for treating lung cancer cells that have become resistant to new anti-cancer agents. view more (2007-04-24)
Fat on chest and upper back increases risk of insulin resistance
Upper trunk fat -- deposits of fat on the chest and back -- is associated with an increased risk of insulin resistance, a condition that is a precursor of type 2 diabetes, according to a study led by researchers at the San Francisco VA Medical Center (SFVAMC). view more (2007-08-20)
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