Drug Resistance Current Events | Drug Resistance News | 2
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Tracing resistance to the antimalarial drug sulfadoxine across Africa
In research published in PLoS Medicine, Cally Roper of the London School of Hygiene & Tropical Medicine and colleagues use genetic analyses to trace the emergence and dispersal of drug-resistant Plasmodium falciparum malaria in Africa. view more (2009-04-14)
Global warming not responsible for malaria increase in East African Highlands
Recent increases in malaria in the East African Highlands cannot be attributed to global warming, researchers at the Department of Zoology at Oxford University have shown. It has long been known that malaria in highland areas is hindered by low temperatures which limit the development of the parasites in the mosquito. Recent upsurges of malaria in... view more... (2002-02-21)
Novel mechanism of taxane resistance
Research Associate Chih-Jian Lih and others working in the laboratory of Dr. Stanley N. Cohen at Stanford University have pinpointed a gene that affects human cancer cells' sensitivity to chemotherapy-an important finding in the effort to increase the effectiveness of chemotherapy. view more (2006-07-17)
Study reveals mechanism for cancer-drug resistance
Using the worm Caenorhabditis elegans, researchers at UT Southwestern Medical Center have discovered a mechanism by which cancer cells become resistant to a specific class of drugs. view more (2006-10-10)
Newfound roadblock to interferon effectiveness against malignant melanoma
Researchers have uncovered a significant contributing factor to interferon resistance of malignant melanoma cells. view more (2005-09-22)
Aspirin treatment failure warning
Treatment failures occur with any drug and aspirin is no exception. Evidence is growing that some people will not respond to the anti-coagulant action of aspirin and the drug will not protect against cardiovascular events despite its regular intake. view more (2005-08-10)
New treatment for food poisoning
A team of researchers working at the University of Bristol has found a potential new treatment for listeriosis, a deadly form of food poisoning. view more (2006-05-12)
New research may overturn conventional wisdom on drug-resistant tuberculosis
A newly released study suggests that the majority of cases of drug-resistant tuberculosis (TB) among patients undergoing treatment for the disease may be due to new infections, not acquired resistance. view more (2007-02-21)
New Stanford list of HIV mutations vital to tracking AIDS epidemic
In a collaborative study with the World Health Organization and seven other laboratories, researchers at the Stanford University School of Medicine have compiled a list of 93 common mutations of the AIDS virus associated with drug resistance that will be used to track future resistance trends throughout the world. view more (2009-03-06)
HIV drug resistance risk in mothers reduced by combination of common drugs
New research from the University of Alabama at Birmingham (UAB) shows that adding a single dose of two common anti-HIV drugs can prevent HIV-positive pregnant women from developing resistance to an entire class of drugs, potentially improving future treatment options. view more (2007-11-12)
Molecular fingerprint of breast-cancer drug resistance can predict response to treatment
A way of predicting which patients will respond well to treatment with a common chemotherapy drug used in breast cancer was unveiled at the European Cancer Conference (ECCO 14) today (Monday 24 September). view more (2007-09-25)
New Treatment Option For Children With Malaria (p 1365)
Combination of the drugs artesunate and amodiaquine could be a new treatment option for children with malaria caused by the parasite Plasmodium falciparum, conclude authors of a fast-track study in this week's issue of THE LANCET. Drug-resistant P. falciparum malaria is a serious problem in sub-Saharan Africa. Chloroquine resistance is a major... view more... (2002-04-17)
BACTERIA DEVELOP RESISTANCE TO NEW ANTIBIOTIC (p1179)
Multi-drug resistant bacteria have caused enormous difficulties worldwide over the past few decades. Scientists had hoped, however, that new drugs currently available for prescription would help to suppress the emergence of super-bugs such as meticillin resistant Staphylococcus aureus that hit the British headlines last year. But, research... view more... (2001-04-11)
Study reveals mechanism for cancer-drug resistance
Using the worm Caenorhabditis elegans, researchers at UT Southwestern Medical Center have discovered a mechanism by which cancer cells become resistant to a specific class of drugs. view more (2006-10-11)
Tamiflu survives sewage treatment
Swedish researchers have discovered that oseltamivir (Tamiflu); an antiviral drug used to prevent and mitigate influenza infections is not removed or degraded during normal sewage treatment. view more (2007-10-03)
Scientists demonstrate feasibility of preventing malaria parasite from becoming sexually mature
Researchers have demonstrated the possibility of preventing the human malaria parasite, Plasmodium falciparum, which is responsible for more than a million malaria deaths a year, from becoming sexually mature. view more (2008-06-03)
Antibiotic resistant bacteria found in fertilizer
Vancomycin resistant enterococci (VRE) have been found in sewage sludge, a by-product of waste-water treatment frequently used as a fertilizer. view more (2009-05-29)
In some cases, genetic resistance takes on a life of its own
For those concerned with the troublesome effects of genetic resistance to drugs and pesticides, the conventional wisdom of evolution offers a reassuring word. view more (2005-08-09)
Advances in HBV DNA assays are key to determine best long-term treatment strategies for Hepatitis B
For the 350 million people chronically infected with HBV, the two therapeutic approaches currently available are immunomodulatory agents and antiviral chemotherapy. The first therapeutic agent was interferon-alpha (IFN-alpha), whose dual mode of action includes both antiviral and immunomodulatory effects. Unfortunately, extended IFN-alpha... view more... (2005-01-10)
Researchers use dirt to stay one step ahead of antibiotic resistance
Dirt may be a key to how bacteria that infect humans develop a resistance to antibiotic drugs. view more (2006-01-20)
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