Drug Resistance Current Events | Drug Resistance News | 4
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Studies identify more effective treatment for malaria control during pregnancy in Africa
A review of previous studies indicates that two doses of a malaria preventive therapy during pregnancy provides substantial benefit to HIV-negative women in Africa, with more frequent dosing apparently necessary for HIV-positive women. view more (2007-06-20)
Confronting the challenge of antimicrobial resistance
Drug resistance is making many diseases increasingly difficult--and sometimes impossible--to treat, according to Anthony S. Fauci, M.D., director of the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health. view more (2008-03-11)
For treating malaria, less drugs may be best drugs
The current dosage of drugs used in treating malaria may be helping the parasites become resistant to the drugs faster, without improving the long-term outcome in patients. view more (2007-11-27)
Poison digs its own grave
Botrytis cinerea (grey mould) has a large arsenal of molecular pumps at its disposal to protect it against toxic substances such as antibiotics, plant defence compounds and fungicides. Dutch researcher Henk-jan Schoonbeek saw how the fungus started to pump out certain toxic substances within just 15 minutes. view more (2004-12-16)
Stopping germs from ganging up on humans
Keeping germs from cooperating can delay the evolution of drug resistance more effectively than killing germs one by one with traditional drugs such as antibiotics, according to new research from The University of Arizona in Tucson. view more (2008-11-20)
Pancreatic cancer: Researchers find drug that reverses resistance to chemotherapy
For the first time researchers have shown that by inhibiting the action of an enzyme called TAK-1, it is possible to make pancreatic cancer cells sensitive to chemotherapy, opening the way for the development of a new drug to treat the disease. view more (2009-09-24)
Superbug genome sequenced
The genome of a newly-emerging superbug, commonly known as Steno, has just been sequenced. The results reveal an organism with a remarkable capacity for drug resistance. The research was carried out by scientists at the Wellcome Trust Sanger Institute near Cambridge and the University of Bristol. view more (2008-05-07)
Study: Delaying evolution of drug resistance in malaria parasite possible
There's no magic bullet for wiping out malaria, but a new study offers strong support for a method that effectively delays the evolution of drug resistance in malaria parasites, a University of Florida researcher says. view more (2008-09-05)
Supersized 'island' of resistance genes discovered in an infectious bacterium
Researchers have discovered a cluster of 45 genes coding for antibacterial drug resistance in the bacterium, Acinetobacter baumannii, a major cause of hospital-acquired infections worldwide. view more (2006-01-13)
Insect Resistance to Bt Crops can be Predicted, Monitored, and Managed
Since 1996, crop plants genetically modified to produce bacterial proteins that are toxic to certain insects, yet safe for people, have been planted on more than 200 million hectares worldwide. view more (2009-11-24)
Poultry consumption, handling are risk factors for antibiotic resistance in humans
Antibiotic use as a livestock growth promoter increases the risk of human antibiotic resistance, a Marshfield Clinic researcher and his colleagues have found. view more (2006-10-11)
European league-tables for antibiotic resistance revealed
Tests of antibiotic resistance in cattle have revealed stark variation across thirteen European countries. The results, published today in BioMed Central's open-access journal Acta Veterinaria Scandinavica, show that major differences were apparent in the occurrence of resistance between countries and between the different antimicrobial agents... view more... (2008-07-08)
MUHC/McGill researchers to WHO: Time to revise tuberculosis treatment guidelines
Tuberculosis is a global threat that affects more than 10 million people each year. Working with colleagues in the United States and France, Dr. Dick Menzies of the Research Institute of the McGill University Health Centre (RI-MUHC) has placed current tuberculosis treatment guidelines under the microscope in a new study. view more (2009-09-15)
Childhood circumstances linked to health in later life
Poor social circumstances in adulthood have been known for some time to increase heart disease risk but less attention has been paid to earlier life circumstances. A study in this week's BMJ finds that adverse social circumstances in childhood, as well as adulthood, are strongly associated with increased risk of insulin resistance, and other heart... view more... (2002-10-09)
When antidepressant drugs stop working: A novel approach
Tolerance to antidepressant drug treatment is an important clinical problem (one third of cases). It may manifest as loss of clinical effect (an antidepressant drug which was working stops doing so) or resistance (a patient, after a drug-free period, fails to respond to an antidepressant drug which was effective before). There is no current... view more... (2003-05-06)
Cell skeleton may hold key to overcoming drug resistance in cancer
Researchers have uncovered a new way in which a cell protein protects cancer cells from a wide range of chemotherapeutic drugs, identifying a possible target for improving treatment outcomes for patients. view more (2007-10-04)
What are the characteristics of clarithromycin-resistant Helicobacter pylori?
Clarithromycin is currently one of the antibiotics used for eradication of Helicobacter pylori. However, reports of H. pylori resistance to this antibiotic are increasing worldwide. view more (2009-07-16)
Fighting drug-resistant flu viruses
Amid reports that swine flu viruses are developing the ability to shrug off existing antiviral drugs, scientists in Japan are reporting a first-of-its kind discovery that could foster a new genre of antivirals that sidestep resistance problems. view more (2009-07-15)
OHSU Cancer Institute researchers identify new approach to help control drug resistance in leukemia
Oregon Health & Science University Cancer Institute researchers have found that an experimental drug known as SGX393 is effective against Gleevec-resistant chronic myeloid leukemia (CML). The results of their study will be published the week of March 24th in the Proceedings of the National Academy of Sciences. view more (2008-03-25)
How does insulin influence resistin?
Obesity is a worldwide health problem directly linked to several diseases such as hypertension and type 2 diabetes. Resistin is a cysteine-rich hormone mainly secreted by adipose tissues and may form a biochemical link between obesity and type 2 diabetes. view more (2008-01-17)
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