Drug Resistant Disease Current Events | Drug Resistant Disease News | 4
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Aspirin treatment failure warning
Treatment failures occur with any drug and aspirin is no exception. Evidence is growing that some people will not respond to the anti-coagulant action of aspirin and the drug will not protect against cardiovascular events despite its regular intake. view more (2005-08-10)
Slow-growing TB bacteria point the way to new drug development
The discovery of a large number of slow-growing Mycobacterium tuberculosis bacteria, which cause tuberculosis (TB), in the lungs of TB patients could be an important step forward in the design of new anti-TB drugs. view more (2009-03-30)
Using a small stockpile of a secondary antiviral drug in a flu pandemic
In a global influenza pandemic, small stockpiles of a secondary flu medication - if used early in local outbreaks - could extend the effectiveness of primary drug stockpiles, according to research made available today ahead of publication in PLoS Medicine. view more (2009-05-01)
Fighting drug-resistant flu viruses
Amid reports that swine flu viruses are developing the ability to shrug off existing antiviral drugs, scientists in Japan are reporting a first-of-its kind discovery that could foster a new genre of antivirals that sidestep resistance problems. view more (2009-07-15)
Cancer stem cells similar to normal stem cells can thwart anti-cancer agents
Current cancer therapies often succeed at initially eliminating the bulk of the disease, including all rapidly proliferating cells, but are eventually thwarted because they cannot eliminate a small reservoir of multiple-drug-resistant tumor cells, called cancer stem cells, which ultimately become the source of disease recurrence and eventual... view more... (2007-06-18)
Hopkins-designed animal TB 'tracker' to speed drug and vaccine studies
Johns Hopkins researchers have developed a novel way to monitor in real time the behavior of the TB bacterium in mouse lungs noninvasively pinpointing the exact location of Mycobacterium tuberculosis. view more (2009-07-23)
New study reveals structure of E. coli multidrug transporter protein
This new study could potentially help researchers find new ways to avoid the problem of multidrug resistance and enhance the potency of existing drug compounds. view more (2006-05-05)
Drug compound leads to death of ovarian cancer cells resistant to chemotherapy
In a discovery that may be useful for maintaining remission in chemo-resistant ovarian cancer, Yale scientists report that pre-clinical studies have shown the drug compound NV-128 can induce the death of ovarian cancer cells by halting the activation of a protein pathway called mTOR. view more (2008-04-18)
OHSU Cancer Institute researchers identify new approach to help control drug resistance in leukemia
Oregon Health & Science University Cancer Institute researchers have found that an experimental drug known as SGX393 is effective against Gleevec-resistant chronic myeloid leukemia (CML). The results of their study will be published the week of March 24th in the Proceedings of the National Academy of Sciences. view more (2008-03-25)
Misuse of common antibiotic is creating resistant TB
Use of a common antibiotic may be undercutting its utility as a first-line defense against drug-resistant tuberculosis (TB). Fluoroquinolones are the most commonly prescribed class of antibiotics in the U.S. and are used to fight a number of different infections such as sinusitis and pneumonia. view more (2009-08-11)
Comprehensive treatment of extensively drug-resistant TB works, study finds
The death sentence that too often accompanies a diagnosis of extensively drug-resistant tuberculosis (XDR-TB) can be commuted if an individualized outpatient therapy program is followed - even in countries with limited resources and a heavy burden of TB. view more (2008-08-07)
Confronting the challenge of antimicrobial resistance
Drug resistance is making many diseases increasingly difficult--and sometimes impossible--to treat, according to Anthony S. Fauci, M.D., director of the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health. view more (2008-03-11)
Researchers identify key gene that may be a marker of breast cancer metastasis
Researchers at Fox Chase Cancer Center have identified an important gene involved in the spread of breast cancer that has developed resistance to long-term estrogen deprivation. view more (2007-04-19)
Early Phase II results show bosutinib safe, effective for CML
A new drug for chronic myelogenous leukemia works for patients who have developed resistance to frontline therapy and causes fewer side effects than other medications in its class, a research team led by scientists at The University of Texas M. D. Anderson Cancer Center reports at the 49th annual meeting of the American Society of Hematology. view more (2007-12-11)
Tracing resistance to the antimalarial drug sulfadoxine across Africa
In research published in PLoS Medicine, Cally Roper of the London School of Hygiene & Tropical Medicine and colleagues use genetic analyses to trace the emergence and dispersal of drug-resistant Plasmodium falciparum malaria in Africa. view more (2009-04-14)
Impaired gene helps nonsmall-cell lung cancer resist drug
Lung cancer cells with a defective version of a potential tumor suppressor gene are highly resistant to attack by a platinum-based drug commonly used to treat the disease. view more (2006-10-02)
Study shows antibiotic-resistant bacteria responsible for increase in muscle infections
Researchers in Houston, Texas have found two bacterial muscle infections common in tropical countries becoming more frequent occurrences along with the emergence of community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA). view more (2006-09-07)
Research Breakthrough In Understanding Treatment-Resistant Depression
CLINICAL NEUROSCIENCE CENTRE: DARTFORD UK A pioneering research study using brain imaging has yielded new clues to help sufferers from severe depression who do not respond to conventional treatment. Around 5 million people in the UK experience depression at any one time. Whilst a number of successful treatments, both pharmacological and... view more... (2003-10-01)
Despite vaccine, public should not get complacent about pneumococcal disease
Although the childhood pneumococcal conjugate vaccine has been a boon in reducing the incidence invasive pneumococcal disease (IPD), the public and the medical community must not get complacent, as non-vaccine strains, some resistant to antibiotics, are on the rise, say scientists at a meeting today in Boston. view more (2008-06-03)
Heeding the WARNing from malaria's past
A global network to monitor drug resistance and guide malaria treatment and prevention policies is being launched. view more (2007-09-06)
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