Drug Resistant Disease Current Events | Drug Resistant Disease News | 5
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Why is long-term therapy required to cure tuberculosis?
Understanding why other bacteria become resistant to antibiotics could hold the key to understanding why TB takes so long to cure, say researchers in a policy paper in PLoS Medicine. view more (2007-03-20)
AMN107 has potent activity in leukemia resistant to Gleevec
The targeted agent AMN107 can produce dramatic benefits in patients with some forms of leukemia that are resistant to Gleevec, the standard therapy for these cancers, say researchers at The University of Texas M. D. Anderson Cancer Center. view more (2005-12-12)
Guidelines needed to prevent spread of infection in European hospitals
National and European guidelines to control the spread of vancomycin resistant enterococci should be drawn up before these bacteria become endemic in European hospitals, argue researchers in this week's BMJ. Vancomycin resistant bacteria have a low virulence but can cause serious infections in transplant patients or those in intensive care units.... view more... (2002-03-13)
HIV drug resistance is increasing in the UK
The prevalence of transmitted HIV drug resistance in the United Kingdom is increasing, according to a study in this week's BMJ. This finding emphasises the urgent need for new approaches to encourage safer sexual behaviour. A total of 69 patients infected with HIV between June 1994 and August 2000 were evaluated for resistance within 18 months of... view more... (2001-05-02)
Protein discovery could unlock the secret to better TB treatment
UCL scientists have found a protein that could unlock the secret to quicker, more effective treatment of TB by waking TB bacteria in the body. Once the TB bacteria are active again, the disease becomes treatable using common drugs like antibiotics. Scientists believe that uncovering the molecular structure of this protein will lead the way to... view more... (2005-02-28)
UAB Study Shows Drug May Fight Biliary Cancers
Laboratory studies by University of Alabama at Birmingham (UAB) researchers have shown that the drug triphendiol (NV-196) causes cell death in pancreatic and bile duct cancer cell lines, slows tumor growth and sensitizes tumors to chemotherapy treatments. view more (2008-04-16)
Jefferson scientists find protein potential drug target for treatment-resistant prostate cancer
Scientists at Jefferson's Kimmel Cancer Center in Philadelphia have found that a signaling protein that is key to prostate cancer cell growth is turned on in nearly all recurrent prostate cancers that are resistant to hormone therapy. view more (2008-01-02)
Henry Ford Hospital study: A MRSA strain linked to high death rates
A strain of MRSA that causes bloodstream infections is five times more lethal than other strains and has shown to have some resistance to the potent antibiotic drug vancomycin used to treat MRSA, according to a Henry Ford Hospital study. view more (2009-11-02)
Paradigm shift needed to combat drug resistance
When people travel, bacteria and other infectious agents travel with them. As about a billion people cross international borders each year, many more billions of the bugs come along for the ride. view more (2009-10-16)
Scientists re-engineer a well-known antibiotic to counter drug resistance
The scientists replaced a single atom from the molecular structure of vancomycin aglycon, a glycopeptide antibiotic that attacks the bacteria by inhibiting cell wall synthesis, significantly increasing the drug's spectrum of activity. view more (2006-02-09)
Infectious diseases experts applaud bill against 'bad bugs'
With extensively drug-resistant tuberculosis, life-threatening drug-resistant respiratory and skin infections, and other "bad bugs" routinely making headlines, infectious diseases physicians are applauding Rep. Jim Matheson (D-UT) and Rep. Michael Ferguson (R-NJ) for introducing H.R. 3697, the Strategies To Address Antimicrobial... view more... (2007-10-01)
Researchers use dirt to stay one step ahead of antibiotic resistance
Dirt may be a key to how bacteria that infect humans develop a resistance to antibiotic drugs. view more (2006-01-20)
Bacteria create aquatic superbugs in waste treatment plants
For bacteria in wastewater treatment plants, the stars align perfectly to create a hedonistic mating ground for antibiotic-resistant superbugs eventually discharged into streams and lakes. view more (2009-05-13)
MRSA head and neck infections increase among children
Rates of antibiotic-resistant head and neck infections increased in pediatric patients nationwide between 2001 and 2006, according to a report in the January issue of Archives of Otolaryngology-Head & Neck Surgery, one of the JAMA/Archives journals. view more (2009-01-20)
The Hsp90-Antifungal Combo, please: Compromising fungi in the immunocompromised
Even the most drug-resistant fungi can be eradicated in multiple in vitro and in vivo models using a lethal combination of an antifungal agent and inhibition of the heat shock protein Hsp90, according to a new study by Whitehead Institute and University of Toronto researchers. view more (2009-02-10)
Nepalese researchers identify cost-effective treatment for drug-resistant typhoid
New research carried out by researchers in Nepal has shown that a new and affordable drug, Gatifloxacin, may be more effective at treating typhoid fever than the drug currently recommended by the World Health Organisation. view more (2007-06-28)
Supersized 'island' of resistance genes discovered in an infectious bacterium
Researchers have discovered a cluster of 45 genes coding for antibacterial drug resistance in the bacterium, Acinetobacter baumannii, a major cause of hospital-acquired infections worldwide. view more (2006-01-13)
Pancreatic cancer: Researchers find drug that reverses resistance to chemotherapy
For the first time researchers have shown that by inhibiting the action of an enzyme called TAK-1, it is possible to make pancreatic cancer cells sensitive to chemotherapy, opening the way for the development of a new drug to treat the disease. view more (2009-09-24)
Drug resistant TB on the increase
The global tuberculosis problem is getting worse - recent figures showed that London has more cases of TB now than it has had for over thirty years. Drug resistance can make this formerly controllable condition almost unmanageable. On 29-30 March, international experts will gather at the Royal Society of Medicine, to highlight the urgent need for... view more... (2001-03-14)
Drug could improve pregnancy outcomes in wider range of women with insulin resistance
Women who are obese, have type 2 diabetes or a family history of type 2 diabetes could one day have more successful pregnancies because of a study at Washington University School of Medicine in St. Louis. view more (2007-09-07)
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