Drug Resistant Disease Current Events | Drug Resistant Disease News | 9
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Not enough is known about treating malaria in pregnancy, researchers say
Few studies compare the effects of different drug regimes in pregnant women, and many of the best studies were conducted in Southeast Asia, where malaria transmission rates are low, says researcher Lois Orton of the University of York in England. view more (2005-07-20)
Drug attacks prostate cancer in mouse model by destroying its blood supply
A medication used to treat other types of cancer strangles drug-resistant, metastatic prostate cancer by cutting off its blood supply. view more (2006-06-07)
Successful cell engineering may lead to mad cow prevention, say researchers
Researchers at Texas A&M University have successfully "knocked down" the expression of possible disease-causing genes in a cloned goat fetus, perhaps paving the way for breeding disease resistance in other animals, even those genes that might cause bovine spongiform encephalopathy (BSE), commonly known as Mad Cow Disease. view more (2006-03-23)
Newfound roadblock to interferon effectiveness against malignant melanoma
Researchers have uncovered a significant contributing factor to interferon resistance of malignant melanoma cells. view more (2005-09-22)
Moores UCSD Cancer Center studying novel leukemia vaccine for high-risk patients
Researchers at the Moores Cancer Center at the University of California, San Diego (UCSD) are conducting clinical trials of a novel therapy aimed at revving up the immune system to combat a particularly difficult-to-treat form of leukemia. view more (2008-11-04)
Community-acquired staph pneumonia appears more common, including MRSA
Preliminary research from the Centers for Disease Control and Prevention (CDC) suggests that community acquired pneumonia (CAP) caused by the Staphylococcus aureus bacterium may be more common than originally suspected, including that caused by antibiotic resistant strains. view more (2008-03-20)
Cell skeleton may hold key to overcoming drug resistance in cancer
Researchers have uncovered a new way in which a cell protein protects cancer cells from a wide range of chemotherapeutic drugs, identifying a possible target for improving treatment outcomes for patients. view more (2007-10-04)
Scientists use gene signatures to match cancer and other diseases with potentially effective drugs
In one of the most ambitious spinoffs of the human genome project, researchers at Dana-Farber Cancer Institute, Children's Hospital Boston, the Broad Institute of Harvard and MIT, and other collaborating centers have unveiled a new, systematic approach to drug discovery that matches diseases with potential treatments using a universal language... view more... (2006-09-29)
Impact of narcotics is greater on mentally ill
Narcotics have an irreversible effect on the brains of people already suffering from mental illness. view more (2009-02-06)
New targeted therapy shows promise in children with metastatic gastrointenstinal stromal tumor
Children with a rare digestive-tract cancer that is resistant to front-line therapy have benefited from a newer targeted therapy that has been shown effective in adults. view more (2006-06-05)
Study finds limited options for backup HIV treatment in some developing countries
Thai researchers have discovered that patients who fail treatment with a commonly used, inexpensive, first-line antiretroviral therapy (ART) are also usually resistant to other, similar drugs, leaving progressively fewer options for replacement therapies. view more (2007-01-09)
Study finds limited options for backup HIV treatment in some developing countries
Thai researchers have discovered that patients who fail treatment with a commonly used, inexpensive, first-line antiretroviral therapy (ART) are also usually resistant to other, similar drugs, leaving progressively fewer options for replacement therapies. view more (2007-01-09)
Combination Drug Therapy Offers Hope For Malaria Treatment (pp 3, 9, 18)
Two articles and a Commentary in this week's issue highlight how combination therapy offers the best hope for tackling drug resistance for the millions of people worldwide affected by malaria. Drug resistance is the main barrier to effective malaria treatment. Artemisinin (extract of sweet wormwood , commonly used in Chinese herbal medicine) and... view more... (2003-12-30)
New drug shows promise in treating drug-resistant prostate cancer
A new therapy for metastatic prostate cancer has shown considerable promise in early clinical trials involving patients whose disease has become resistant to current drugs. view more (2009-04-10)
Malaria-resistant mosquitoes battle disease with 'molecular warhead'
A team led by UT Southwestern Medical Center researchers has discovered why some mosquitoes are resistant to malaria, a finding that may one day help fight a disease that afflicts and kills millions of people. view more (2007-07-09)
Disinfectants can make bacteria resistant to treatment
Chemicals used in the environment to kill bacteria could be making them stronger, according to a paper published in the October issue of the journal Microbiology. Low levels of these chemicals, called biocides, can make the potentially lethal bacterium Staphylococcus aureus remove toxic chemicals from the cell even more efficiently, potentially... view more... (2008-10-06)
Medication eases obsessive-compulsive symptoms
A medication used to ease symptoms of amyotrophic lateral sclerosis, or Lou Gehrig's disease, also is helpful in treating people with treatment-resistant obsessive-compulsive disorder (OCD), according to a pilot study at Yale School of Medicine. view more (2005-08-01)
New mechanism identified for resistance to targeted lung cancer drugs
An international research team, led by investigators from the Massachusetts General Hospital (MGH) Cancer Center and Dana-Farber Cancer Institute (DFCI), has found a new way that some lung tumors become resistant to treatment with targeted therapy drugs like Iressa and Tarceva. view more (2007-04-27)
Enzyme inhibitor takes an unexpected approach toward blocking cancer-promoting protein
Scientists at Fox Chase Cancer Center have discovered a unique method of attack that may be used to inhibit signaling enzymes called kinases, which often have a role in sustaining drug-resistant cancerous cells. They have confirmed that IPA-3, a small molecular inhibitor of a kinase called PAK1, targets the enzyme's regulatory domain, mimicking... view more... (2009-09-08)
Drug breakthrough for psoriasis sufferers
An international team led by a dermatologist at The University of Manchester has found that treatment with the emerging drug infliximab, marketed as Remicade, can quickly and significantly improve psoriasis symptoms. view more (2005-10-14)
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