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metaGen and RNAx Announce Target Validation Agreement
metaGen Pharmaceuticals and RNAx announced today the signing of a target validation agreement. Under the terms of the agreement RNAx provides metaGen with access to RNA interference validation technology (RNAi). metaGen will employ this technology to validate proprietary gene targets relevant for... view more (2003-03-25)

atugen AG and metaGen Pharmaceuticals Sign Target Validation Agreement
Berlin, Germany, February 11, 2003 - atugen AG and metaGen Pharmaceuticals GmbH announced today that they have signed an agreement to evaluate the application of atugen's target validation technology in research and development of metaGen's novel cancer drug targets. Under the terms of the... view more (2003-02-11)

Scientists model 900 cell receptors, drug targets
In an important step toward accelerating drug discovery, researchers have created computer models of more than 900 cell receptors from a class of proteins known to be important drug targets.   view more (2006-02-17)

Scientists pool information to boost understanding of drug action
As a result of the Human Genome Project, scientists now know the human DNA codes for about 20,000-25,000 genes, each of which could be a target for the development of new medicines. However, most scientists believe that only about 10% of these genes are likely targets for the drugs of the future.   view more (2005-12-01)

Can cancer drugs combine forces?
Individuals with chronic myeloid leukemia (CML) are treated first with a drug known as imatinib (Gleevec), which targets the protein known to cause the cancer (BCR-ABL).   view more (2007-08-17)

Morphochem And Fox Chase Cancer Center Enter Into Collaboration To Develop Novel Treatments For Cancer
Morphochem AG, a leader in chemical genomics, and Fox Chase Cancer Center (Philadelphia, US), a comprehensive cancer center, have entered into a research collaboration that will leverage the strengths of both organizations to develop new treatments for cancer. The collaboration is wide ranging and... view more (2002-10-16)

The BMJ guide to wickedness
Need tips on "sexing up" poor performance data to meet government targets? Want advice to guarantee your dodgy drug sells like hot cakes? Or are you simply after ways to make a dubious but compelling submission to NICE? Several articles in this week's Christmas issue of the BMJ offer a... view more (2003-12-17)

Research offers hope for alcoholics
Scientists at Melbourne's Howard Florey Institute have discovered a system in the brain that stops an alcoholic's craving for alcohol, as well as prevent relapse once they have recovered from alcohol addiction.   view more (2006-12-13)

Research offers hope for alcoholics
Scientists at Melbourne's Howard Florey Institute have discovered a system in the brain that stops an alcoholic's craving for alcohol, as well as prevent relapse once they have recovered from alcohol addiction.   view more (2006-12-13)

10 per cent of human genome is target for new drugs
Around 10 per cent of the human genome can be targeted for the development of new drugs, according to top pharmaceutical industry scientists speaking at the BA Festival of Science at the University of Glasgow today [3rd September 2001]. Speaking at the From genes and cells to healthcare forum... view more (2001-08-30)

£2 Million of Yeast Could Triple Available Drug Treatments
Researchers are to employ the humble yeast cell to greatly increase – perhaps even triple - the number of drug treatments for common diseases such as allergies, asthma, obesity, type 2 diabetes, schizophrenia, heart disease, osteoporosis and cancer.   view more (2003-02-05)

Rapid, Functional, Genome-wide Drug Discovery Enabled
Munich, Germany, November 18th, 2003. Xantos Biomedicine AG, a leading functional biology and drug discovery company, announced that it has expanded its collection of full-length human cDNA clones in mammalian expression vectors to 35,000, representing one of the world's largest collections. The... view more (2003-11-18)

Xerion Pharmaceuticals Enters Into Option Agreement For Cancer Targets From Tufts University
Martinsried, Germany and Cambridge, MA, February 26, 2003 - Xerion Pharmaceuticals announced today that it has acquired exclusive rights to cancer targets resulting from the collaboration between Xerion and the laboratory of Daniel G. Jay, Ph.D., Professor of Physiology at Tufts University. Xerion... view more (2003-02-26)

Academy cautious over Energy White Paper
The Royal Academy of Engineering's Vice President, Mr Phil Ruffles FREng, today welcomed the publication of the Energy White Paper but cautioned that the targets for renewables, reduction in emissions and energy efficiency were all economically and technologically demanding. The Academy has been on... view more (2003-02-24)

NHS Stop-Smoking Services are insufficient to deliver national smoking targets
NHS Stop-Smoking Services are insufficient to deliver national smoking targets, and Government smoking targets are themselves insufficient for the poorest communities, says a study published online by the BMJ today.   view more (2005-03-16)

Identifying cancer genes - will it really lead to better treatment?
Copenhagen, Denmark: A systematic trawl through the human genome looking for the abnormalities that drive cancer is already producing promising results, a scientist told ECCO 12 - The European Cancer Conference in Copenhagen today (Tuesday 23 September). Dr. Michael Stratton, Director of the Cancer... view more (2003-09-21)

NHS breast screening targets need to be reviewed
Women who attend the NHS breast screening programme have a higher risk of breast cancer than women who decline to participate, finds a study in this week's BMJ. This "self selection" for screening has important implications for NHS breast cancer detection targets. Researchers at the... view more (2001-07-18)

EU Funding Helps Fight Liver Cancer
The fight against liver cancer, one of the leading causes of cancer death worldwide, is being helped by 2.5 million euros from the EU's Framework Programme.   view more (2005-02-22)

Prison drug services in Kent, Surrey and Sussex failed by lack of aftercare available to prisoners after release
The greatest threat to the success of prison-based drug treatments is the lack of aftercare available to prisoners after their release, according to a review published by the Centre for Health Service Studies at the University of Kent. The review, which is part of a wider programme of work... view more (2003-07-11)

Drosophila drug screen for fragile X syndrome finds promising compounds and potential drug targets
Scientists using a new drug screening method in Drosophila (fruit flies), have identified several drugs and small molecules that reverse the features of fragile X syndrome -- a frequent form of mental retardation and one of the leading known causes of autism.   view more (2008-03-10)

Study points to genes responsible for malaria parasite's survival in attempts to eradicate it
Malaria is a nasty and often fatal disease, which may lead to kidney failure, seizures, permanent neurological damage, coma, and death. There are four types of Plasmodium parasites that cause the disease, of which falciparum, the subject of the recent study, is the most deadly.   view more (2006-06-20)

Animal Study Identifies Promising New Target for Brain Tumor Therapy
A drug that targets the body's immune cells may be effective in treating malignant brain tumors, according to a new study led by researchers at Duke's Preston Robert Tisch Brain Tumor Center. In animal models, the drug re-engaged the body's cancer-damaged immune system.   view more (2007-05-09)

Diabetes targets will be impractical in routine practice
Targets due to be set as part of the national service framework for diabetes in England and Wales will be impractical for use in routine clinical care, according to an article in this week’s BMJ.   view more (2002-06-26)

IUPUI scientists report first 3-D view of anti-cancer agent
Researchers from the Indiana University School of Medicine and the Purdue School of Science at Indiana University-Purdue University Indianapolis have created the first three-dimensional image of how a well-established chemotherapy agent targets and binds to DNA.   view more (2008-03-19)

Gene expression profiling of dengue virus infection in cell lines and patients
Researchers at the Novartis Institute for Tropical Diseases and the Genome Institute of Singapore have identified new host genes associated with dengue virus infection, which may open new avenues to developing a drug to treat the disease.   view more (2007-11-07)
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