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Drug Targets Current Events | Drug Targets News | 2
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Patient expectations of care may exceed government targets
Patients may have expectations for access to primary care in excess of current government targets, finds a study in this week's BMJ. Patients also have high expectations of continuity of care. Researchers analysed data from general practice research studies and routine quality assessment activities... view more (2003-01-29)

New report: The truth about drug innovation
A new report co-authored by Manhattan Institute senior fellow Benjamin Zycher, and Joseph DiMasi, and Christopher-Paul Milne, researchers from the Tufts Center for the Study of Drug Development, examines case histories for thirty-five important pharmaceutical innovations.   view more (2008-06-25)

Enzyme may hold key to improved targeting of cancer-fighting drugs
A critical enzyme used to prepare a powerful cancer-killing agent may be able to help drug makers better target the cells the natural product attacks, according to findings published in the May 23 edition of the Journal of Biological Chemistry.   view more (2008-05-30)

Boehringer Ingelheim enters into multi-target drug discovery collaboration with Morphochem.
Morphochem AG, a leader in the evolutionary discovery of small molecule drugs announced that it has entered into a research collaboration with Boehringer Ingelheim, a leading pharmaceutical company with a focus on human pharmaceuticals and animal health. Morphochem will apply its drug discovery... view more (2004-02-04)

Researchers discover how antibiotic inhibits bacterial growth
Researchers at the University of Illinois at Chicago, in collaboration with research teams from Pharmacia & Upjohn and Pfizer, have discovered precisely how the antibiotic linezolid inhibits bacterial growth.   view more (2007-05-11)

Structure of key cancer drug target identified
Researchers from Monash's Department of Biochemistry and Molecular Biology have determined the structure of the protein JAK2 kinase, a discovery with huge implications for the design and development of new cancer drugs.   view more (2005-10-26)

Nicotinic receptors may be important targets for treatment of multiple addictions
For years, scientists have known that some people are biologically more susceptible to drug addiction than others, but they have only been able to speculate why.   view more (2007-08-16)

Mayo Clinic Cancer Center — individualizing treatment for multiple myeloma patients
Researchers at Mayo Clinic Cancer Center, in cooperation with industry partners, have, for the first time, identified tumor specific alterations in the cellular pathway by which the multiple myeloma drug bortezomib (Velcade) works, and they have identified nine new genetic mutations in cancer cells... view more (2006-12-11)

Researchers identify new cell targets for preventing growth of breast and other tumors
Researchers at the Lineberger Comprehensive Cancer Center at the University of North Carolina at Chapel Hill have discovered new targets for cancer treatment aimed at blocking a key step in tumor progression.   view more (2008-04-24)

Researchers identify new cell targets for preventing growth of breast and other tumors
Researchers at the Lineberger Comprehensive Cancer Center at the University of North Carolina at Chapel Hill have discovered new targets for cancer treatment aimed at blocking a key step in tumor progression.   view more (2008-04-24)

Morphochem Signs Deal With AstraZeneca To Develop Novel Anti-thrombotics
Munich, November 21st 2002 "¦. Morphochem AG, a leader in evolutionary discovery of small molecule drugs, has entered into a research collaboration with AstraZeneca AB (Sweden) wherein Morphochem will apply its drug discovery engine, the MOREsystem™, to the discovery of compounds with... view more (2002-11-21)

New possibilities for drug design
An article in Journal of Physics B, published on 7 July 2003 by the Institute of Physics, reports on a new technique which could in future help scientists working in rational drug design (a way of tailoring a new drug to fit the structure of the protein it targets) to develop drugs more... view more (2003-07-04)

New molecular insight into amboebic dysentery
In the June 15th issue of G&D, Dr. Sinisa Urban (Johns Hopkins University School of Medicine) and colleagues reveal a potential role for the rhomboid enzyme, EhROM1, in the pathogenesis of the enteric protozoan parasite, E. histolytica.   view more (2008-06-16)

Scientists demonstrate feasibility of preventing malaria parasite from becoming sexually mature
Researchers have demonstrated the possibility of preventing the human malaria parasite, Plasmodium falciparum, which is responsible for more than a million malaria deaths a year, from becoming sexually mature.   view more (2008-06-03)

2005 global tuberculosis targets may be out of reach (p 814)
An article in this week's issue of THE LANCET cautions that key targets for tuberculosis control-due to be reached by next year-are unlikely to be met unless renewed strategic action and financial support can be secured. Tuberculosis remains a leading cause of death among adults in less-developed... view more (2004-03-03)

Xerion Pharmaceuticals and Arius Research sign colon cancer collaboration
Martinsried, Germany and Cambridge, Massachusetts, USA - October 15, 2002"¦Xerion Pharmaceuticals and ARIUS Research Inc. of Canada announced today that they would combine their respective strengths in functional proteomics and antibody discovery to jointly develop products for cancer therapy.... view more (2002-10-15)

UCSB researchers discover shape matters to macrophages
Researchers at UC Santa Barbara have made a surprising discovery: phagocytosis depends more on particle shape than size.   view more (2006-03-22)

Antipsychotic drug may block addiction, UIC researchers find
Researchers at the University of Illinois at Chicago have discovered that a long-approved oral antipsychotic drug can stop the addictive properties of opioid painkillers in mice.   view more (2006-02-09)

A&E time targets may be affecting patient care
Researchers at the University of Sheffield have questioned the effectiveness of time targets in improving care in Accident and Emergency (A&E) Departments, following a study which has suggested that the pressure to meet time targets has affected the way that patients are dealt with in A&E. It found... view more (2005-04-20)

New Cancer Treatment Targets Both Tumor Cells and Blood Vessels
It takes more than one punch to fight tumors. Often, tumors have more than one way of surviving, and attacking the tumor alone is not enough.   view more (2008-06-19)

Assembling the jigsaw puzzle of drug addiction
Using an integrative meta-analysis approach, researchers from the Center for Bioinformatics at Peking University in Beijing have assembled the most comprehensive gene atlas underlying drug addiction and identified five molecular pathways common to four different addictive drugs.   view more (2008-01-07)

Researchers explore the antidepressant effects of ketamine
Drug treatments for depression can take many weeks for the beneficial effects to emerge. The excruciating and disabling nature of depression highlights the urgency of developing treatments that act more rapidly.   view more (2008-02-22)

Nottingham academic welcomes new proposals for consultation on target setting
A University of Nottingham professor is backing proposals published today that recommend the Government should consult more widely before setting performance targets for public services such as education, hospitals and the police. Professor Colin Talbot, in the University's School of Sociology and... view more (2003-07-21)

Hybrigenics Launches Pharma Industry’s First Proteomics Database For Hiv Drug Development Proprietary Hiv Bioinformatics Platform At Keystone Symposia Meeting
Paris, France - Hybrigenics, the functional proteomics company, announces the launch of the world’s most comprehensive combined protein-protein interactions “map” between the human immunodeficiency virus (HIV) and its host cell in humans. This represents the first time that a... view more (2001-03-29)

University of Helsinki to coordinate two large EU research projects
The European Union has granted nearly 25 MEUR to two large-scale interdisciplinary research projects coordinated by the University of Helsinki. The project leaders are professor Raimo Tuominen from the UH's Faculty of Pharmacy and Academy professor Kari Alitalo from UH's Molecular and Cancer... view more (2004-08-24)
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