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Aspirin protects patients at high risk of heart attack or stroke
Aspirin (or another antiplatelet drug) protects patients at high risk of serious vascular events, such as heart attack or stroke, and should be considered routinely for all such patients, concludes a study in this week's BMJ. view more (2002-01-09)
Risk and outcome similar for bypass surgery, drug-eluting stents
Drug-eluting stent therapy and bypass surgery for coronary artery disease have about the same risk for a major cardiac event within 30 days after the procedures, researchers reported at the American Heart Association's 8th Annual Conference on Arteriosclerosis, Thrombosis and Vascular Biology. view more (2007-04-20)
How the US drug safety system should be changed
In the May 3 issue of the Journal of the American Medical Association, Brian L. Strom, MD, MPH, Professor of Public Health and Preventive Medicine and Chair of the Department of Biostatistics and Epidemiology at the University of Pennsylvania School of Medicine, analyzes the limitations of the current system of drug-safety monitoring and proposes... view more... (2006-05-04)
How Long Should Drug Treatment Of Depression Last?
Three Italian researchers (Drs Fava, Ruini and Tossani of the University of Bologna) challenge the Australian guidelines for treatment of depression. The beyondblue guidelines for treating depression in primary care by Ellis and Smith are intended to assist both healthcare professionals and consumers. While they provide several helpful... view more... (2003-05-26)
Researchers explore long-term adolescent vulnerability to drugs
As part of efforts to understand drug abuse, Georgia State University researchers are finding that adolescent rats appear to be less vulnerable to the long-term effects of withdrawal and relapse in certain types of drug use than rats that take the drugs in adulthood. view more (2009-09-17)
Theory shows mechanism behind delayed development of antibiotic resistance
Inhibiting the "drug efflux pumps" in bacteria, which function as their defence mechanisms against antibiotics, can mask the effect of mutations that have led to resistance in the form of low-affinity drug binding to target molecules in the cell. view more (2009-05-06)
New research may overturn conventional wisdom on drug-resistant tuberculosis
A newly released study suggests that the majority of cases of drug-resistant tuberculosis (TB) among patients undergoing treatment for the disease may be due to new infections, not acquired resistance. view more (2007-02-21)
Early reports of thrombosis after insertion of drug-eluting stent (pp 1466, 1519)
Authors of a research letter in this week's issue of THE LANCET highlight how the use of drug-eluting stents (DES) may carry a risk of subsequent thrombosis if stenting is accompanied by a withdrawal of antiplatelet therapy. view more (2004-10-20)
U of M study finds new insight on therapy for a devastating parasitic disease
University of Minnesota Medical School researchers have discovered an important new insight into how a commonly prescribed drug may work to treat those infected by a parasitic flatworm. view more (2009-06-24)
Antipsychotic drug may block addiction, UIC researchers find
Researchers at the University of Illinois at Chicago have discovered that a long-approved oral antipsychotic drug can stop the addictive properties of opioid painkillers in mice. view more (2006-02-09)
Seven out of every ten drug addict men admit they consume drugs to increase their sexual pleasure
A study carried out at the University of Granada has analysed the connection between drug consumption and sexual performance by means of a survey of 120 drug addict characters. The work has revealed that, paradoxically, most of the men who consume drugs to lose their sexual inhibition use cocaine, a narcotic substance which incapacitates at sexual... view more... (2009-03-05)
Stigma increases likelihood that drug users reoffend
Punitive policies intended to reduce drug use by making life difficult for convicted users are counterproductive and actually lead to a vicious spiral of drug use and reincarceration. view more (2009-05-08)
DOES TREATING HIGH BLOOD PRESSURE SAVE LIVES? (P1305)
Findings of a meta-analysis published in this week's issue of The Lancet emphasise that blood pressure control is important and that on average, all antihypertensive drugs have similar long-term efficacy and safety. One of the most common causes of death in the developed world is cardiovascular disease (heart attacks and strokes). Measures to... view more... (2001-10-17)
Drug commonly used for alcoholism curbs urges of pathological gamblers
A drug commonly used to treat alcohol addiction has a similar effect on pathological gamblers - it curbs the urge to gamble and participate in gambling-related behavior, according to a new research at the University of Minnesota. view more (2008-06-16)
Prescription Dose Changes - Are initially recommended doses too high?
Over 20% of prescription drugs undergo substantial reductions in their recommended dosages, relative to the doses initially recommended, according to two papers published in the August issue of Pharmacoepidemiology and Drug Safety, available online on 14 August 2002. These changes reveal a discrepancy between the dosage information gathered from... view more... (2002-08-13)
STUDY HIGHLIGHTS VALUE OF NURSES FOR IDENTIFYING ADVERSE DRUG REACTIONS (p 1345)
Issue 19 April 2003 Embargoed 0001 h (London time) 18 April 2003 Authors of a research letter in this week's issue of THE LANCET highlight the important role that nurses can play in detecting adverse drug reactions (ADR). Policies vary across countries in authorising nurses to report ADR; the UK National Health Service recently expanded the... view more... (2003-04-16)
Detection Of Antibodies Could Identify MS Patients Who Do Not Respond Well To Interferon Beta (P1184)
Danish research published in this week's issue of THE LANCET highlights how the detection of antibodies to interferon beta-the first choice treatment for multiple sclerosis patients-could be important in identifying patients who do not respond well to interferon beta, with implications for the provision of alternative drug therapy. Interferon beta... view more... (2003-10-08)
Study reveals mechanism for cancer-drug resistance
Using the worm Caenorhabditis elegans, researchers at UT Southwestern Medical Center have discovered a mechanism by which cancer cells become resistant to a specific class of drugs. view more (2006-10-10)
Patients Unaware of Drug Safety Withdrawals
Researchers call for better notification to reduce risk to patients Two weeks after cerivastatin was publicly withdrawn nearly 80% of the patients sampled in a public hospital clinic were unaware of the withdrawal according to results (1) to be published in the December issue of Pharmacoepidemiology and Drug Safety, available online on 31 October... view more... (2002-10-24)
Medical profession attempts to "clean up" relations with drug industry
As entanglement between doctors and drug grows, a two-part article by journalist Ray Moynihan in this week’s BMJ explores the brewing conflicts at one of the world’s leading medical institutions over how to redefine relations with big pharmaceutical companies. view more (2003-05-28)
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