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Atypical antipsychotic drugs for dementia may be associated with small increased risk of death
Patients with dementia who took atypical antipsychotic drugs had a slightly increased risk of death compared to patients who took placebo, according to a meta-analysis published in the October 19 issue of JAMA. view more (2005-10-19)
Effectiveness of first renin inhibitor drug for treating hypertension is limited
Hypertension is a serious condition affecting millions. Currently there are seven classes of drugs used to reduce blood pressure. view more (2007-05-10)
Safety claims of new arthritis drugs may be misleading
Popular arthritis drugs, known as selective COX 2 inhibitors, may not be superior to traditional non-steroidal anti-inflammatory drugs, conclude researchers in this week’s BMJ. view more (2002-05-28)
Acetaminophen or acetylsalicylic acid increases risk of developing chronic kidney failure
People who regularly use high dosages of pain-relievers or antipyretic drugs containing acetaminophen (paracetamol) or acetylsalicylic acid run an increased risk of developing permanent reduced kidney function (chronic renal failure). This was found in a nation-wide Swedish research study published on December 20 in The New England Journal of... view more... (2001-12-21)
Two drugs may stabilize plaques in atherosclerosis
Two drugs that a Wake Forest University School of Medicine research team has been investigating for lupus for several years may stabilize atherosclerotic plaque in the walls of arteries and help avert heart attacks and strokes. view more (2006-11-13)
Ace Inhibitors Could Slow Muscle Decline (p 926)
Angiotensin-converting enzyme (ACE) inhibitors, a class of drugs used to lower blood pressure, could also be protective against the decline in muscle strength in elderly women suggest authors of a study in this week's issue of THE LANCET. ACE inhibitors are known to prevent the decline in physical function in patients with congestive heart failure... view more... (2002-03-13)
New clues to how major weight-loss drugs work
Some of the most important weight-loss drugs work by enhancing the effect of the brain chemical serotonin. These include sibutramine (trade name Meridia) and fenfluramine, which was recalled after the combination with dexfenfluramine, called fen-phen, was linked to potentially fatal heart valve abnormalities. view more (2006-07-20)
Blood-pressure-lowering drugs should not be limited to people with high blood pressure
Blood pressure lowering drugs should be offered to anyone old enough to be at risk of a heart attack or stroke (or who is otherwise known to be at risk), regardless of their blood pressure. view more (2009-05-20)
New Drugs Prevent Scarring After Glaucoma Eye Surgery
Highly innovative new drugs that can prevent scarring in the eye after glaucoma surgery have been discovered by a London-based team of scientists, who report today in the journal Nature Biotechnology.* By targeting more than one aspect of the scarring process at the same time, the team has been able to use the drugs safely and successfully in... view more... (2004-07-16)
Diabetes drugs increase risk of heart failure, research shows
A class of drugs commonly used to treat type 2 diabetes may double the risk of heart failure, according to a new analysis by researchers at Wake Forest University School of Medicine and colleagues. view more (2007-07-27)
Protein discovery could unlock the secret to better TB treatment
UCL scientists have found a protein that could unlock the secret to quicker, more effective treatment of TB by waking TB bacteria in the body. Once the TB bacteria are active again, the disease becomes treatable using common drugs like antibiotics. Scientists believe that uncovering the molecular structure of this protein will lead the way to... view more... (2005-02-28)
Scientists solve mystery of polyketide drug formation
Many top-selling drugs used to treat cancer and lower cholesterol are made from organic compounds called polyketides, which are found in nature but historically difficult for chemists to alter and reproduce in large quantities. view more (2008-04-02)
People are averse to taking drugs
Many people are averse to taking drugs unless absolutely necessary and would prefer lifestyle change to medication, according a study in this week's BMJ. Researchers in Liverpool interviewed a small group of family doctors, nurses, and lay people to explore their views on the minimum benefit they thought would justify drug treatment to prevent... view more... (2003-10-08)
Rising rates of bleeding from ulcers in last decade despite changes in treatment
Hospital admissions for bleeding ulcers rose throughout the 1990s despite changes in drug treatment, reveals a study in Gut. view more (2002-03-11)
A new computational technique predicts side-effects of a major cancer drug
Researchers at the University of California San Diego have developed a novel computer technique to search for the side effects of major pharmaceuticals. view more (2007-11-28)
Cost control measures limit patient and physician choice in psychotropic medications
A new Brandeis University study published online in Clinical Therapeutics suggests that private health plans increasingly rely on escalating copayments to manage drug costs, as opposed to administrative controls. view more (2007-03-02)
Nanoballs deliver drugs
Dutch researcher Cristianne Rijcken has developed a new type of biodegradable nanoparticle. The spherical structures can encapsulate various fat-soluble medicines, which makes it easier to target tumour tissue. view more (2007-10-25)
MS patients not receiving medications to slow disease progression, research shows
Neurologists at Wake Forest University Baptist Medical Center have found that many patients diagnosed with multiple sclerosis (MS) are not taking or being prescribed drugs approved to treat the disease. view more (2007-04-17)
Treating bedwetting in children
Embargoed until 19.00 hours Sunday 10 August 2003 The latest issue of Effective Health Care focuses on how best to treat bedwetting in children. Bedwetting (nocturnal enuresis) affects many children and their families. Although it has a high rate of spontaneous remission, bedwetting may bring social and emotional stigma, stress and inconvenience... view more... (2003-08-04)
Study reveals mechanism for cancer-drug resistance
Using the worm Caenorhabditis elegans, researchers at UT Southwestern Medical Center have discovered a mechanism by which cancer cells become resistant to a specific class of drugs. view more (2006-10-10)
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