Embryonic Development Current Events | Embryonic Development News | 8
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Method to deliver molecules within embryonic stem cells improves differentiation
Embryonic stem cell therapies have been proposed for regenerative medicine and tissue replacement after injury or disease. However, the inability of stem cells to efficiently develop into the desired specific cell type - such as muscle, skin, blood vessels, bone or neurons - now limits the potential clinical utility of this therapy. view more (2008-04-10)
Cross-species transplant in rhesus macaques is step toward diabetes cure for humans
With an eye on curing diabetes, scientists at Washington University School of Medicine in St. Louis have successfully transplanted embryonic pig pancreatic cells destined to produce insulin into diabetic macaque monkeys - all without the need for risky immune suppression drugs that prevent rejection. view more (2007-10-19)
New way to make stem cells avoids risk of cancer
A team of scientists has advanced stem cell research by finding a way to endow human skin cells with embryonic stem cell-like properties without inserting potentially problematic new genes into their DNA. view more (2009-03-27)
Left-right wiring determined by neural communication in the embryonic worm
Most animals appear symmetrical at first glance, but we're full of internal lop-sidedness. From the hand used to pick up a pencil or throw a baseball, to where language is generated in the brain, to the orientation of our internal organs, humans are a glut of asymmetries. view more (2007-05-18)
Human stem cells provide a new model for Lou Gehrig's disease
Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a devastating condition in which motor neuron degeneration causes progressive loss of movement and muscle tone, leading to death. view more (2009-02-23)
Making memories that last a lifetime
Neurobiologists have discovered a mechanism by which the constantly changing brain retains memories—from that dog bite to that first kiss. They have found that the brain co-opts the same machinery by which cells stably alter their genes to specialize during embryonic development. view more (2007-03-15)
What makes stem cells tick?
Investigators at the Burnham Institute for Medical Research (Burnham) and The Scripps Research Institute (TSRI) have made the first comparative, large-scale phosphoproteomic analysis of human embryonic stem cells (hESCs) and their differentiated derivatives. view more (2009-08-07)
Mice cloned from skin cells
Healthy and viable mice that survive until adulthood have, for the first time, been cloned from adult stem cells. Scientists from Rockefeller University, including Howard Hughes Medical Institute investigator Elaine Fuchs, used cells called keratinocyte stem cells, which represent a new model system for cloning. view more (2007-02-13)
Stem cells provide clues to cancer spread
Scientists have made a breakthrough in understanding how cancers spread in what could lead to new ways of beating the disease. view more (2007-05-23)
A transplant in time
In hemophilia, a mutated gene prevents the production of a critical blood-clotting protein. Treatments for hemophilia and other such genetic diseases, when they exist, may consist of risky blood transfusions or expensive enzyme replacement therapy. view more (2007-01-02)
Molecular alliance that sustains embryonic stem cell state
One of the four ingredients in the genetic recipe that scientists in Japan and the U.S. followed last year to persuade human skin cells to revert to an embryonic stem cell state, is dispensable in ES cells, thanks to the presence of a molecular alliance between a specific group of key proteins known as transcription factors. view more (2008-03-05)
How stem cells are regulated
Researchers from Biotech Research & Innovation Centre (BRIC) at University of Copenhagen have identified a new group of proteins that regulate the function of stem cells. The results are published in the new issue of Cell. view more (2007-02-23)
Researchers find molecule that inhibits regrowth of spinal nerve cells
A molecule that helps the body's motor nerve cells grow along proper paths during embryonic development also plays a major role in inhibiting spinal-cord neurons from regenerating after injury, researchers at UT Southwestern Medical Center have found. view more (2005-07-12)
First reconstitution of an epidermis from human embryonic stem cells
Stem cell research is making great strides. This is yet again illustrated by a study carried out by the I-STEM* Institute (I-STEM/ Inserm UEVE U861/AFM), published in the Lancet on 21 November 2009. The I-STEM team, directed by Marc Peschanski has just succeeded in recreating a whole epidermis from human embryonic stem cells. view more (2009-11-20)
Adult stem cells from human cord umbilical cord blood successfully engineered to make insulin
In a fundamental discovery that someday may help cure type 1 diabetes by allowing people to grow their own insulin-producing cells for a damaged or defective pancreas, medical researchers here have reported that they have engineered adult stem cells derived from human umbilical cord blood to produce insulin. view more (2007-05-29)
Gladstone researchers hone in on differentiation of heart stem cells
A team of scientists from the Gladstone Institute of Cardiovascular Disease (GICD) has identified a key factor in heart development that could help advance gene therapy for treating cardiac disorders. view more (2005-12-16)
UCLA stem cells scientists make electrically active motor neurons from iPS cells
Stem cells scientists at UCLA showed for the first time that human induced pluripotent stem (iPS) cells can be differentiated into electrically active motor neurons, a discovery that may aid in studying and treating neurological disorders. view more (2009-02-25)
Landmark study unlocks stem cell, DNA secrets to speed therapies
In a groundbreaking study led by an eminent molecular biologist at Florida State University, researchers have discovered that as embryonic stem cells turn into different cell types, there are dramatic corresponding changes to the order in which DNA is replicated and reorganized. view more (2008-10-13)
Of mice and men: Stem cells and ethical uncertainties
The recent creation of live mice from induced pluripotent stem cells (iPSCs) not only represents a remarkable scientific achievement, but also raises important issues, according to bioethicists at The Johns Hopkins University's Berman Institute of Bioethics. view more (2009-10-30)
Venous origin of the mammalian lymphatic vasculature
In the October 1 issue of G&D, Dr. Guillermo Oliver (St. Jude Children's Research Hospital) and colleagues present new evidence to resolve a century-old debate over the origin of the mammalian lymphatic vasculature. view more (2007-10-01)
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