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Embryonic Stem Cells | Embryonic Stem Cells News, Research and Current Events
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New cell type identified in cancer development
Scientists have discovered a new type of cell that appears to play a role in the development of cancer - a highly volatile, precancerous stem cell that can either remain benign or become malignant, depending upon environmental cues.   view more (2007-03-14)

AN EYE FOR AN EYE: Using stem cells to treat damaged eyes and a rare skin disorder
Doctors and scientists in Italy have shown how stem cells can be used to treat damaged eyes and, in combination with gene therapy, a rare and debilitating skin disease.   view more (2007-10-23)

Computation to unravel how genes are regulated and shed light on how cells become different
A closer alliance between computational and experimental researchers is needed to make progress towards one of biology's most challenging goals, understanding how epigenetic marks contribute to regulation of gene expression.   view more (2008-04-11)

Scientists ask whether microscaffolding can help stem cells rebuild brain after stroke damage
Inserting tiny scaffolding into the brain could dramatically reduce damage caused by strokes the UK National Stem Cell Network Annual Science Meeting will hear today (10 April).   view more (2008-04-10)

Human muscle-derived stem cells effective in animal models of incontinence
Human muscle-derived cells, pluripotent stem cells found in muscle, have been used to cure stress urinary incontinence in animal models, a finding which signals that these cells are prime candidates to treat the condition in adults.   view more (2005-09-01)

Transplanted brain cells hold promise for Parkinson's disease
Transplanted neural stem cells hold promise for reducing the destruction of dopaminergic cells that occurs in Parkinson's disease and for replacing cells lost to the disease, scientists say.   view more (2006-12-05)

Aggressive stem cells might improve transplant outcome
Investigators at St. Jude Children's Research Hospital have demonstrated in mice a way that might reduce the time it takes for a bone marrow transplant to rebuild a child's immune system, and so reduce the risk of potentially fatal virus infections that can occur during this time.   view more (2006-12-08)

Injecting stem cells from a woman's own muscle may effectively treat urinary incontinence
In the first clinical study of its kind in North America, women with stress urinary incontinence (SUI) were treated using muscle-derived stem cell injections to strengthen deficient sphincter muscles responsible for the condition.   view more (2006-05-22)

A stem cell type supposed to be crucial for angiogenesis and cancer growth does not exist?
Angiogenesis, the growth of new blood vessels, is a central process in diverse physiological and pathological situations such as healing of wounds and traumas, cardiovascular disorders, inflammatory conditions such as rheumatoid arthritis, and in cancer growth.   view more (2008-04-23)

Researchers discover 'sticky' proteins fuse adult stem cells to cardiac muscle, repairing hearts
Cardiologists are increasingly using adult stem cells in clinical trials to repair hearts following heart attacks, but no one has understood how the therapy actually works.   view more (2007-02-16)

UC Irvine scientists find new way to sort stem cells
UC Irvine scientists have found a new way to sort stem cells that should be quicker, easier and more cost-effective than current methods. The technique could in the future expedite therapies for people with conditions ranging from brain and spinal cord damage to Alzheimer's and Parkinson's diseases.   view more (2007-12-21)

Origen publishes in Nature a robust and versatile method for creating transgenic chickens
Origen Therapeutics announced today that it has succeeded in developing a robust and versatile technology for genetically modifying chickens that, for the first time, puts avian transgenics on a par with transgenic mice.   view more (2006-06-08)

Dartmouth professor makes case for ethically universal stem cell lines
Human embryonic stem cells (hESC), those very young cells that are a biological blank slate, have the potential to become more specialized, contributing to the workings of a wide variety of organs and tissues.   view more (2007-06-08)

Stem cell transplantation procedure results in long-term survival for amyloidosis patients
Researchers from the Stem Cell Transplant Program and the Amyloid Treatment and Research Program at Boston University Medical Center (BUMC) have found that high-dose chemotherapy and blood stem cell transplantation can result in long-term survival for patients diagnosed with primary systemic light... view more (2007-08-08)

Sickle cell disease corrected in human models using stem cell-based gene therapy
In a study to be published in the January 2006 issue of Nature Biotechnology, researchers led by a team of scientists at Memorial Sloan-Kettering Cancer Center have devised a novel strategy that uses stem cell-based gene therapy and RNA interference to genetically reverse sickle cell disease (SCD)... view more (2005-12-29)

New research could help us deliver genes for new bone formation
UK scientists are working on new methods to regenerate cartilage and bone by delivering genes to stem cells within the body to instruct them to turn into bone cells.   view more (2005-09-29)

PET and Bioluminescent Imaging Aid Evaluation of Stem Cells' Potential for New Ways to Treat Disease
Using positron emission tomography (PET) imaging with bioluminescence-the light produced by a chemical reaction within an organism-researchers are starting to understand the behavior of transplanted or implanted stem cells that may one day be used to develop new treatments for disease.   view more (2007-12-07)

Ireland Cancer Center researchers advance stem cell gene therapy
Ireland Cancer Center of University Hospitals Case Medical Center researchers have recently made great strides in stem cell gene therapy research by transferring a new gene to cancer patients, via their own stem cells, with the ultimate goal of being able to use stronger chemotherapy treatment with... view more (2007-12-13)

OHSU discovery sheds light into how stem cells become brain cells
Researchers at the Oregon National Primate Research Center at Oregon Health & Science University (OHSU) have discovered one key gene that appears to control how stem cells become various kinds of brain cells.   view more (2005-12-15)

Studies find general mechanism of cellular aging
Three separate studies confirm a gene that suppresses tumor cell growth also plays a key role in aging.   view more (2006-09-07)

Stanford researchers find culprit in aging muscles that heal poorly
Communication is critical. Garbled in, garbled out, so to (mis-)speak. Workers who get incomplete instructions produce an incomplete product, and that's exactly what happens with the stem cells in our aging muscles.   view more (2007-08-10)

Bone marrow may be source of new egg-cell generation in adult mammals
Last year a group of Massachusetts General Hospital (MGH) researchers announced surprising findings that female mice - contrary to longstanding theories of mammalian reproductive physiology - retained the ability to make new egg cells or oocytes into adulthood.   view more (2005-07-28)

Stem Cell Study for Patients with Heart Attack Damage Seeks to Regenerate Heart Muscle
Rush cardiologists are hoping that transplanted stem cells can regenerate damaged heart muscle in those who experience a first heart attack. The study involves an intravenous infusion of adult mesenchymal stem cells from healthy donor bone marrow that might possibly reverse damage to heart tissue.   view more (2006-04-21)

Research shows promise for using stem cell transplantation to treat patients with severe lupus
About half of patients with severe lupus that was refractory to standard treatment and who underwent autologous stem cell transplantation to improve their immune system have substantial improvement in disease activity after several years.   view more (2006-02-01)

Technique to arrest urinary incontinence
The University Hospital of Navarra is to carry out clinical trials for urinary incontinence using the intraurethral injection of myoblasts (adult stem cells obtained by means of a biopsy of the patient).   view more (2006-10-04)

Study shows isolation of stem cells may lead to a treatment for hearing loss
Have you ever walked by someone listening to their i-Pod loud enough for you recognize the song? Studies have shown noise-induced hearing loss is going to become the next big epidemic affecting our younger generation though the effects won't show until it is too late to treat.   view more (2007-04-06)

Stomach stem cell discovery could bring cancer insights
Scientists have identified and described stem cells specific to several tissues and organs of the body - key master cells that give rise to the specialized cell types characteristic of that organ.   view more (2007-10-04)

Starting over: Wnt reactivates dormant limb regeneration program
Chop off a salamander's leg and a brand new one will sprout in no time. But most animals have lost the ability to replace missing limbs. Now, a research team at the Salk Institute for Biological Studies has been able to regenerate a wing in a chick embryo - a species not known to be able to regrow... view more (2006-11-20)

Potential for Adult Stem Cells to Repair Hearts Damaged by Severe Coronary Artery Disease Investigated by Rush Cardiologists
Rush University Medical Center is one of the first medical centers in the country, and currently the only site in Illinois, participating in a novel clinical trial to determine if a subject's own stem cells can treat a form of severe coronary artery disease.   view more (2007-02-02)

A transplant in time
In hemophilia, a mutated gene prevents the production of a critical blood-clotting protein. Treatments for hemophilia and other such genetic diseases, when they exist, may consist of risky blood transfusions or expensive enzyme replacement therapy.   view more (2007-01-02)

Molecule prompts blood stem cells to help repair heart damage in animal model
Researchers at UT Southwestern Medical Center have for the first time used drug-treated blood stem cells to repair heart damage in an animal model, results that might point to methods for healing injuries from heart attacks or disease.   view more (2008-04-15)

Brittlestar provides new model for stem cell research
The brittlestar, Amphiura filiformis, is a close relative of the starfish and can regenerate lost arms in a matter of weeks.   view more (2006-04-10)

New directions in tissue repair and regeneration
PHILOSOPHICAL TRANSACTIONS B MAY ISSUE New directions in tissue repair and regeneration - a discussion meeting issue organised and edited by Jeremy Brockes and Paul Martin This volume will consider new information on regeneration and wound healing as biological mechanisms in a variety of... view more (2004-05-04)

Neural stem cell gene plays crucial role in eye development
Scientists at the University of North Carolina at Chapel Hill have demonstrated that normal development of the eye requires the right amount of a neural stem cell gene be expressed at the right time and place.   view more (2006-05-16)

Short RNA strand helps exposed skin cells protect body from bacteria, dehydration and even cancer
Every minute, 30,000 of our outermost skin cells die so that we can live. When they do, new cells migrate from the inner layer of the skin to the surface of it, where they form a tough protective barrier.   view more (2008-03-03)

Adult stem cell changes underlie rare genetic disease associated with accelerated aging
Adult stem cells may provide an explanation for the cause of a Hutchinson-Gilford Progeria Syndrome (HGPS), a rare disease that causes premature aging in children, according to researchers at the National Cancer Institute (NCI), part of the National Institutes of Health (NIH).   view more (2008-03-03)

Mad-cow culprit maintains stem cells
What do mad cow disease and stem cell research have in common? Whitehead Institute scientists have found that the same protein that causes neurodegenerative conditions such as bovine spongiform encephalopathy (mad cow disease) is also important for helping certain adult stem cells maintain... view more (2006-01-31)

Researchers aim to cut future need for liver transplants
University of Edinburgh scientists have identified primitive liver cells —possibly dormant from the earliest developmental stage of a human being — which have the potential to mature into different cells types and help repair a failing liver.   view more (2006-07-07)

Key to zebrafish heart regeneration uncovered
When a portion of a zebrafish's heart is removed, the dynamic interplay between a mass of stem cells that forms in the wound and the protective cell layer that covers the wound spurs the regeneration of functional new heart tissue.   view more (2006-11-03)

Findings advance use of adult stem cells for replacement bone
In a significant advance for regenerative medicine, researchers at Rice University have discovered a new way to culture adult stem cells from bone marrow such that the cells themselves produce a growth matrix that is rich in important biochemical growth factors.   view more (2006-02-14)

Stem cells give clues to understanding cancer and make breakthrough in childhood leukaemia
Scientists in Switzerland are uncovering new clues about how cancer cells grow - and how they can be killed - by studying stem cells, 'blank' cells that have the potential to develop into fully mature or 'differentiated' cells and other scientists in UK have made a breakthrough in understanding the... view more (2008-02-14)

UK scientists set their sights on cure for AMD
A groundbreaking surgical therapy capable of stabilising and restoring vision in the vast majority of patients who currently suffer blindness through Age-Related Macular Degeneration (AMD) is to be taken to clinical trial by scientists and clinicians at the UCL Institute of Ophthalmology,... view more (2007-06-06)

First production of human monoclonal antibodies in chicken eggs published in Nature Biotechnology
Origen Therapeutics today announced the first published scientific report of fully functional, human sequence monoclonal antibodies (mAbs) produced in chickens. The antibodies were expressed solely in the chicken oviduct and deposited into egg white in concentrations of 1-3 milligrams per egg.   view more (2005-08-29)

Human stem cells show promise against fatal children's diseases
Scientists have used human stem cells to dramatically improve the condition of mice with a neurological condition similar to a set of diseases in children that are invariably fatal, according to an article in the June issue of the journal Cell Stem Cell.   view more (2008-06-05)

Researchers find stem-cell therapy effective in targeting metastatic cancer
Patients with advanced cancer that has spread to many different sites often do not have many treatment options, since they would be unable to tolerate the doses of treatment they would need to kill the tumors.   view more (2006-12-21)

Using Nanoparticles, In Vivo Gene Therapy Activates Brain Stem Cells
Using customized nanoparticles that they developed, University at Buffalo scientists have for the first time delivered genes into the brains of living mice with an efficiency that is similar to, or better than, viral vectors and with no observable toxic effect, according to a paper published this... view more (2005-07-26)

Factor stimulates cartilage growth from stem cells
A novel growth factor significantly improves the ability of specialized stem cells derived from human fat to be transformed into cartilage cells, according to Duke University Medical Center and Pratt School of Engineering researchers.   view more (2006-04-05)

Run amok enzyme causes same problems in both humans and fruit flies
An enzyme found at elevated levels in several human cancers has been linked to abnormal tumor growth in fruit flies, a discovery that provides a new model for understanding the link between stem cell biology and cancer, according to researchers at the University of Oregon.   view more (2006-12-19)

Daisies lead scientists down path to new leukemia drug
A new, easily ingested form of a compound that has already shown it can attack the roots of leukemia in laboratory studies is moving into human clinical trials, according to a new article by University of Rochester investigators in the journal, Blood.   view more (2007-10-03)

Jefferson scientists uncover role of cancer stem cell marker: controlling gene expression
Scientists at Jefferson's Kimmel Cancer Center in Philadelphia have made an extraordinary advance in the understanding of the function of a gene previously shown to be part of an 11-gene "signature" that can predict which tumors will be aggressive and likely to spread.   view more (2008-01-18)
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