Endoplasmic Reticulum Current Events | Endoplasmic Reticulum News
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Legionnaire's bacterial proteins work together to survive
Proteins within the bacteria that cause Legionnaire's disease can kidnap their own molecular "coffin" and carry it to a safe place within the cell, ensuring their survival, Yale School of Medicine researchers report in Nature Wednesday. view more (2007-10-24)
Visualizing virus replication in 3 dimensions
Dengue fever is the most common infectious disease transmitted by mosquitoes - some 100 million people around the world are infected. Researchers at the Hygiene Institute at Heidelberg University Hospital were the first to present a three-dimensional model of the location in the human cell where the virus is reproduced. view more (2009-05-08)
MSU scientists find new gene that helps plants beat the heat
Michigan State University plant scientists have discovered another piece of the genetic puzzle that controls how plants respond to high temperatures. That may allow plant breeders to create new varieties of crops that flourish in warmer, drier climates. view more (2008-10-07)
Unfolded proteins may protect cells from dying
When cells get stressed, their proteins go unfolded. It's a reaction with a straightforward name: the unfolded protein response. Now, new research from Rockefeller University shows that this phenomenon actually serves a protective role; rather than a sign that the cell has given up, it may be a mechanism by which the cells cope with adversity. view more (2006-12-27)
St. Jude finds mechanism for faulty protein disposal
A discovery by St. Jude Children's Research Hospital scientists offers new insights into how myeloma cells dispose of defective or excess proteins and could lead to new cancer treatments. view more (2007-12-07)
Animal study suggests inadequate sleep may exacerbate cellular aging in the elderly
Researchers at the University of Pennsylvania School of Medicine have shown that the unfolded protein response, which is a reaction to stress induced by sleep deprivation, is impaired in the brains of old mice. view more (2008-06-30)
Unmasking the "Foreman" Of The Golgi Apparatus
The cell is a highly organized factory where each constituent has its place and a role to play. If one piece of this machinery falters, the whole cell is imperiled. The least anomaly may result in an uncontrolled cell likely to engender a variety of diseases, such as cancers. At the Institut Curie, CNRS researchers, in collaboration with a group... view more... (2004-08-05)
Why don't all moles progress to melanoma?
Everyone has moles. Most of the time, they are nothing but a cosmetic nuisance. But sometimes pigment-producing cells in moles called melanocytes start dividing abnormally to form a deadly form of skin cancer called melanoma. view more (2006-10-03)
Not all fat is created equal
A Temple University study finds fat in obese patients is "sick" when compared to fat in lean patients. view more (2008-08-28)
Researchers aim to over-stress already taxed mantle cell lymphoma cells
Cancer cells are already stressed by the fast pace they require to grow and spread and scientists believe a little more stress just may kill them. view more (2008-11-11)
Vaccine-producing 'plant-factories'
A research team at the Consejo Superior de Investigaciones CientÃficas (CSIC) has discovered a new route for the transport of proteins in plant cells, a discovery that will enable the biotechnological design of plant factories. Amongst other applications, these can be used to produce oral vaccines which, upon being ingested, will be able to... view more... (2006-11-08)
Little-known protein found to be key player
Italian and U.S. biologists this week report that a little-understood protein previously implicated in a rare genetic disorder plays an unexpected and critical role in building and maintaining healthy cells. view more (2009-07-30)
How Toxoplasma gondii gets noticed
Researchers provide insight into how Toxoplasma gondii, a common parasite of people and other animals, triggers an immune response in its host. view more (2009-01-20)
Botched production of insulin molecule may lead to diabetes
Picture a pretzel factory production line, with conveyer belts carrying the dough, formed into unbaked pretzels, down to the oven to be cooked. Now imagine what would happen if pretzel dough started to overflow the mixer and oozed as a blob onto the conveyor, misshapen, and sticking fast to the dough of the other fully formed, unbaked pretzels. view more (2007-10-02)
The battle for CRTC2: How obesity increases the risk for diabetes
Obesity is probably the most important factor in the development of insulin resistance, but science's understanding of the chain of events is still spotty. view more (2009-06-22)
Aspirin discovery may improve cancer treatments
Salicylates, including aspirin, are used to treat a range of inflammatory conditions and can be used to prevent diseases such as cancer, but the way aspirin works is not yet fully understood. view more (2007-04-06)
Mutations in the insulin gene can cause neonatal diabetes
Mutations in the insulin gene can cause permanent neonatal diabetes, an unusual form of diabetes that affects very young children and results in lifelong dependence on insulin injections. view more (2007-09-11)
Prolonged stress sparks ER to release calcium stores and induce cell death in aging-related diseases
Study shows prolonged stress sparks ER to release calcium stores and induce cell death in aging-related diseases such as atherosclerosis, diabetes and neurodegeneration. view more (2009-09-14)
Genetics of ALS progression
An upcoming paper from Drs. Hidenori Ichijo and Hideki Nishitoh (The University of Tokyo) and colleagues lends new and valuable insight into the genetics of ALS. view more (2008-06-02)
Researchers discover cell's 'quality control' mechanism
Researchers in Japan and Canada have discovered a key component of the quality control mechanism that operates inside human cells - sometimes too well. The breakthrough has significant implications for the development of new treatments for cystic fibrosis (CF) and some other hereditary diseases, the researchers say. Their results were published... view more... (2008-07-30)
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