Endothelial Current Events | Endothelial News
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Hemangioma arteriovenous malformations or how endothelial cells escape apoptosis (programmed cell death).
Hemangiomas included several types of vascular abnormalities. The first classification of vascular abnormalities was proposed in 1982. Since angiography is becoming a common investigation, a better identification of the vascular abnormalities was possible. Hemangiomas are frequent in children and are present in 10 to 12 new born babies.... view more... (1999-09-14)
Building the blood-brain barrier
Construction of the brain's border fence is supervised by Wnt/b-catenin signaling, report Liebner et al. in The Journal of Cell Biology. view more (2008-10-27)
Laser surgery does not appear to have long-term effects on corneal cells
Laser eye surgery to correct vision problems does not appear to be associated with lasting changes to cells lining the inside of the cornea at nine years after the procedure. view more (2009-11-10)
Increased risk of coronary heart disease among UK Indian Asians may be genetic
The increased rates of premature coronary heart disease among UK Indian Asians may be due to genetic or other as yet undiscovered risk factors, rather than the usual suspects, suggests research in Heart. view more (1999-04-26)
Study supports reason for concern in childhood and adolescent obesity
Study findings presented at the May 2008 Pediatric Academic Societies and Asian Society for Pediatric Research Joint Meeting indicate that childhood and adolescent obesity negatively impacts vascular endothelial function, which relates to cardiac health. view more (2008-05-12)
ESC Congress 2004: Embryonic endothelial progenitor cells help overcome myocardial infarction in pigs
Myocardial infarction, caused by coronary artery occlusion, can lead up to loss of muscle tissue of the heart and functional detriment, even at times where rapid reperfusion strategies like PTCA or thrombolysis are at hand. In the study presented here, we investigated embryonic endothelial progenitor cells as therapy for ischemia reperfusion... view more... (2004-08-30)
Healthy blood vessels may prevent fat growth
The cells lining blood vessels are known to be important for maintaining health, but researchers at the Indiana University School of Medicine believe these cells may perform an unsuspected task - controlling the development of fat cells. view more (2008-09-22)
Use of statins shows improvement in erectile performance of some men
Researchers at the University of Pennsylvania School of Medicine say preliminary results of a small study show promise in improving erectile dysfunction (ED) in men who had shown minimal reaction to Viagra. view more (2006-02-22)
A Possible Mechanism For Pre-eclampsia? (p 1511)
Results of a preliminary study in this week's issue of THE LANCET suggest that there may be future tests to determine whether pregnant women are at risk of developing pre-eclampsia, a serious disorder of late pregnancy. Up to 8% of pregnant women develop pre-eclampsia (pregnancy-induced high blood pressure and presence of protein in the urine,... view more... (2003-04-30)
Human vascular system in mice
The formation of new blood vessels, or angiogenesis, is an Achilles' heel of tumor growth, because tumors depend on the supply of oxygen and nutrients for survival. view more (2008-04-15)
New Developments in Angiogenic Therapy Emerging from Oxford
Angiogenesis, the growth of new blood vessels, is important in the healthy body for healing wounds and, in females, for the monthly reproductive cycle and during pregnancy. It is controlled in the body through the use of the body’s own angiogenesis inhibitors and stimulators. In certain diseases the body is unable to control blood vessel... view more... (2002-08-23)
Circulating blood cells are important predictors of cancer spread in children
Endothelial progenitor cells may play a role in the start and progression of metastatic disease in children with cancer. view more (2009-07-15)
Potential diagnostic marker indicates effectiveness of anti-angiogenic drugs
If an anti-angiogenic drug is successfully starving a cancer patient's tumor to death, the number of endothelial cells circulating in the individual's bloodstream will decrease, thus providing a potential biomarker for gauging the medication's effectiveness. view more (2006-09-18)
ABC-transporters expressed on endothelial cell membranes efflux anti-HIV drugs
Researchers at Tulane University Medical Center in New Orleans (USA) have discovered that drug-efflux pumps, belonging to the ATP-binding cassette (ABC) transporter family, are constitutively expressed on vascular endothelial cells. view more (2008-08-27)
A novel mechanism of action for anti-tumor agent, CA4P
Anti-angiogenic agents have been successful in the clinic for blocking the growth of solid tumors. However, these agents used in combination with chemotherapy have improved the survival of patients with cancers by only several months. view more (2005-10-07)
Bone marrow cells can heal nerves in diabetes model
Transplanting cells that replenish blood vessels can also restore nerve function in an animal model of diabetic neuropathy, Emory researchers have found. view more (2009-02-05)
A stem cell type supposed to be crucial for angiogenesis and cancer growth does not exist?
Angiogenesis, the growth of new blood vessels, is a central process in diverse physiological and pathological situations such as healing of wounds and traumas, cardiovascular disorders, inflammatory conditions such as rheumatoid arthritis, and in cancer growth. view more (2008-04-23)
Possible new compound for treatment of cerebral malaria
In a paper published online in PLoS Medicine researchers from Marseille describe the effects of a new compound that may be a future treatment for patients with cerebral malaria. view more (2005-08-23)
Bio-engineering of blood vessels
Blood vessel prostheses work best when the biochemical and mechanical properties match reality as much as possible and when they are made of biodegradable material. To this end tissue technologists grow natural vascular wall cells, endothelial cells, in a biodegradable tube made of collagen. According to Professor Istv'¡n Vermes tissue... view more... (2002-04-16)
A few squares of dark chocolate a day may stave off artery hardening in smokers
Dark chocolate may stave off artery hardening in smokers, and a few squares every day could potentially cut the risk of serious heart disease. view more (2005-12-20)
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