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Bio-engineering of blood vessels
Blood vessel prostheses work best when the biochemical and mechanical properties match reality as much as possible and when they are made of biodegradable material. To this end tissue technologists grow natural vascular wall cells, endothelial cells, in a biodegradable tube made of collagen. According to Professor Istv'¡n Vermes tissue... view more... (2002-04-16)
A few squares of dark chocolate a day may stave off artery hardening in smokers
Dark chocolate may stave off artery hardening in smokers, and a few squares every day could potentially cut the risk of serious heart disease. view more (2005-12-20)
The benefits of green tea in reducing an important risk factor for heart disease
More evidence for the beneficial effect of green tea on risk factors for heart disease has emerged in a new study reported in the latest issue of European Journal of Cardiovascular Prevention and Rehabilitation. view more (2008-07-02)
Ultra-low-dose aspirin might decrease bleeding severity in portal hypertension
In rats with portal hypertension, ultra-low-dose aspirin has shown a normalizing effect of platelet-endothelial cell alterations and bleeding time. Further, this effect is mediated by Cyclooxygenase 2 inhibition. view more (2007-10-10)
New device detects heart disease using less than one drop of blood
Testing people for heart disease might be just a finger prick away thanks to a new credit card-sized device created by a team of researchers from Harvard and Northeastern universities in Boston. view more (2009-06-02)
Japanese Researchers Get to the Heart of Atherosclerosis
Using positron emission tomography (PET), the medical isotope 15O-water and cold pressor tests, Japanese researchers were able to detect the beginnings of atherosclerosis—before the disease became clinically evident. view more (2006-06-05)
UIC researchers make promising finding in severe lung disease
Researchers at the University of Illinois at Chicago have identified a novel function for an enzyme that plays a role in the tissue injury in acute respiratory distress syndrome, also known as ARDS. view more (2008-06-30)
The vasculature emerges as a potential therapeutic target in treating ADPKD liver cysts
As part of an effort to develop effective medical therapies that block the progression of liver cyst growth in patients with Autosomal Dominant Polycystic Kidney Disease (ADPKD), researchers at the University of Colorado Anschutz Medical Center have found that the liver cyst walls develop and maintain a vasculature as they grow out from the body... view more... (2009-09-24)
Even mild sleep apnea increases cardiovascular risk
People with even minimally symptomatic obstructive sleep apnea (OSA) may be at increased risk for cardiovascular disease because of impaired endothelial function and increased arterial stiffness, according to a study from the Oxford Centre for Respiratory Medicine in the UK. view more (2008-10-27)
Preventing or reversing inflammation after heart attack, stroke may require 2-pronged approach
Researchers at Albany Medical College are releasing results of a study this week that they say will help refocus the search for new drug targets aimed at preventing or reversing the devastating tissue inflammation that results after heart attack and stroke. view more (2010-03-01)
Molecule helps cells plug leaks following lung injury
Researchers at the University of Illinois at Chicago College of Medicine have identified a molecule that plays a critical role in the recovery of lung tissue following severe injury. view more (2006-09-15)
Modest gain in visceral fat causes dysfunction of blood vessel lining in lean, healthy humans
When lean healthy young adults gained about 9 pounds, the functioning of their blood vessel lining became impaired -- but shedding the weight restored proper functioning, according to a Mayo Clinic research report. view more (2007-11-06)
Study explains why patients with OSA are at higher risk for cardiovascular disease
Researchers have found that patients with obstructive sleep apnea (OSA) have higher levels of a type of dead cells (apoptotic cells) from the lining (endothelium) of their blood vessels circulating in their bloodstream than people who do not have OSA. view more (2007-06-01)
New study introduces the prospect for concurrent antiangiogenic/antitumorigenic therapy
Today, during the 39th Annual Meeting of the American Association for Dental Research, convening at the Walter E. Washington Convention Center in Washington, DC, lead researcher M. Tong, The Ohio State University, will present a poster of a study titled "Epithelial-to-Endothelial Transition: An Epithelial Phenotypic Modulation Facilitating... view more... (2010-03-05)
UVa Scientists Hot on Trail of Therapies for Deadly Lung Failure
Researchers at the University of Virginia Health System have identified a molecular target, or receptor, for potential drugs to treat acute respiratory distress syndrome (ARDS), a sudden and life-threatening failure of the lung. view more (2006-02-22)
Penn Researchers Unlock Molecular Origin of Blood Stem Cells
A research team led by Nancy Speck, PhD, Professor of Cell and Developmental Biology at the University of Pennsylvania School of Medicine, has identified the location and developmental timeline in which a majority of bone marrow stem cells form in the mouse embryo. view more (2009-01-12)
Mayo Clinic researchers use magnetic attraction to improve stents, reduce blood clot risk
Mayo Clinic heart researchers have devised a new strategy to improve the effectiveness and safety of heart stents, which are used to open narrowed blood vessels and have been the recent subject of clotting concerns. view more (2006-11-03)
Vitamin A pushes breast cancer to form blood vessel cells
Researchers at Georgetown University Medical Center have discovered that vitamin A, when applied to breast cancer cells, turns on genes that can push stem cells embedded in a tumor to morph into endothelial cells. These cells can then build blood vessels to link up to the body's blood supply, promoting further tumor growth. view more (2008-07-16)
Gladstone scientists identify single microRNA that controls blood vessel development
Scientists from the Gladstone Institute of Cardiovascular Disease (GICD) and UCSF have identified a key regulatory factor that controls development of the human vascular system, the extensive network of arteries, veins, and capillaries that allow blood to reach all tissues and organs. view more (2008-08-12)
ESC Congress 2004: PERTINENT - PERindopril - Thrombosis, InflammatioN, Endothelial dysfunction and Neurohormonal activation Trial
A Sub-Study of the EUROPA Study Evaluation of the Effect of Perindopril on Endothelial Function view more (2004-08-31)
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