Endothelial Current Events | Endothelial News | 8
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Normalizing tumor vessels to improve cancer therapy
Chemotherapy drugs often never reach the tumors they're intended to treat, and radiation therapy is not always effective, because the blood vessels feeding the tumors are abnormal-"leaky and twisty" in the words of the late Judah Folkman, MD, founder of the Vascular Biology program at Children's Hospital Boston. view more (2008-08-26)
MEDIA INVITATION: The first European Vascular Genomics Network conference - Media briefing
CAMBRIDGE - On Monday December 13th at 12:00 noon, at the New Hall College in Cambridge (UK), the European Vascular Genomics Network (EVGN) organizes a media briefing in occasion of "The First European Vascular Genomics Network conference". view more (2004-12-01)
Twin studies reveal genetic components leading to cardiac and kidney disease
Daniel O'Connor, M.D., Professor of Medicine and Pharmacology at the University of California, San Diego (UCSD) School of Medicine has studied about 265 twin pairs over the past few years, which has led him to some surprising discoveries. view more (2007-04-18)
A new significance of LVD and angiogenic MVD is identified in human primary SCRC
Lymphangiogenesis and angiogenesis are critical processes for tumor growth, invasion and metastasis. Angiogenesis has established its role in the development and progression of a variety of malignancies, playing a crucial role in the dissemination of the tumor cells. view more (2008-01-17)
Transplanted fat cells restore function after spinal cord injury
A study published in the current issue of CELL TRANSPLANTATION (Vol.17, No. 8) suggests that mature adipocytes - fat cells - could become a source for cell replacement therapy to treat central nervous system disorders. view more (2008-12-11)
Scientists discover why cornea is transparent and free of blood vessels, allowing vision
Scientists at the Harvard Department of Ophthalmology's Schepens Eye Research Institute and Massachusetts Eye and Ear Infirmary (MEEI) are the first to learn why the cornea, the clear window of the eye, is free of blood vessels-a unique phenomenon that makes vision possible. view more (2006-07-18)
Stem cells in adult testes provide alternative to embryonic stem cells for organ regeneration
Easily accessed and plentiful, adult stem cells found in a male patient's testicles might someday be used to create a wide range of tissue types to help him fight disease -- getting around the need for more controversial embryonic stem cells. view more (2007-09-20)
Novel findings about neovessel formation
The main role in new findings about neovessel formation is played by a protein called tissue factor. This factor turns out to have both a stimulatory function and an inhibitory function in the generation of blood vessels. Normally these two functions neutralize each other, but in diseases like retinopathy - where unwanted blood vessels grow into... view more... (2004-05-10)
Bioengineers create stable networks of blood vessels
Yale biomedical engineers have created an implantable system that can form and stabilize a functional network of fine blood vessels critical for supporting tissues in the body, according to a report in the Proceedings of the National Academy of Sciences. view more (2006-03-01)
Cholesterol-lowering Drug May Also Reduce Risk of Blood Clots
Statin drugs, commonly used to lower high cholesterol blood levels, have been shown to possibly decrease the risk for thrombotic complications of antiphospholipid syndrome (APS), a disease associated with blood clotting and recurrent fetal loss. Research conducted on animal models, has shown success in using the drug fluvastatin to inhibit the... view more... (2004-11-10)
Blood vessel cells are instructed to form tube-like structures
How do blood vessel cells understand that they should organise themselves in tubes and not in layers? A research group from Uppsala University shows for the first time that a special type of "instructor" molecule is needed to accomplish this. These findings, published in the scientific journal Blood, might be an important step towards... view more... (2008-08-29)
Castrate resistant prostate cancer: New therapeutic approaches
Today Dr. Martin Gleave of the Vancouver Prostate Centre in Canada gave a lecture about new approaches to treat castrate-resistant prostate cancer (CRCP) during the 24th Annual Congress of the European Association of Urology in Stockholm, Sweden. view more (2009-03-23)
Key process in gene regulation occurs in blood platelets, Univeristy of Utah researchers find
In a discovery that upends a longstanding tenet of human biology, University of Utah School of Medicine researchers have shown that a key process in gene regulation can occur in human platelets, unique cells that are unusual because they don't have a nucleus (anucleate). view more (2005-08-12)
Drug therapy reduces neuroblastoma tumor growth in pre-clinical investigation
Researchers from the Children's Cancer Hospital at The University of Texas M. D. Anderson Cancer Center have discovered a new drug combination that significantly hinders tumor growth in neuroblastoma, a childhood cancer. view more (2009-04-27)
Air pollution link to clogged arteries
Should we be watching our exposure to airborne pollution as well as our cholesterol levels" Research now indicates that air pollution has a role to play in atherosclerosis (artery hardening), which can contribute to heart attacks or strokes. view more (2007-07-26)
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