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Hemangioma arteriovenous malformations or how endothelial cells escape apoptosis (programmed cell death).
Hemangiomas included several types of vascular abnormalities. The first classification of vascular abnormalities was proposed in 1982. Since angiography is becoming a common investigation, a better identification of the vascular abnormalities was possible. Hemangiomas are frequent in children and are present in 10 to 12 new born babies.... view more... (1999-09-14)
Building the blood-brain barrier
Construction of the brain's border fence is supervised by Wnt/b-catenin signaling, report Liebner et al. in The Journal of Cell Biology. view more (2008-10-27)
Healthy blood vessels may prevent fat growth
The cells lining blood vessels are known to be important for maintaining health, but researchers at the Indiana University School of Medicine believe these cells may perform an unsuspected task - controlling the development of fat cells. view more (2008-09-22)
ESC Congress 2004: Embryonic endothelial progenitor cells help overcome myocardial infarction in pigs
Myocardial infarction, caused by coronary artery occlusion, can lead up to loss of muscle tissue of the heart and functional detriment, even at times where rapid reperfusion strategies like PTCA or thrombolysis are at hand. In the study presented here, we investigated embryonic endothelial progenitor cells as therapy for ischemia reperfusion... view more... (2004-08-30)
Bone marrow cells can heal nerves in diabetes model
Transplanting cells that replenish blood vessels can also restore nerve function in an animal model of diabetic neuropathy, Emory researchers have found. view more (2009-02-05)
Increased risk of coronary heart disease among UK Indian Asians may be genetic
The increased rates of premature coronary heart disease among UK Indian Asians may be due to genetic or other as yet undiscovered risk factors, rather than the usual suspects, suggests research in Heart. view more (1999-04-26)
Human vascular system in mice
The formation of new blood vessels, or angiogenesis, is an Achilles' heel of tumor growth, because tumors depend on the supply of oxygen and nutrients for survival. view more (2008-04-15)
Possible new compound for treatment of cerebral malaria
In a paper published online in PLoS Medicine researchers from Marseille describe the effects of a new compound that may be a future treatment for patients with cerebral malaria. view more (2005-08-23)
Circulating blood cells are important predictors of cancer spread in children
Endothelial progenitor cells may play a role in the start and progression of metastatic disease in children with cancer. view more (2009-07-15)
Potential diagnostic marker indicates effectiveness of anti-angiogenic drugs
If an anti-angiogenic drug is successfully starving a cancer patient's tumor to death, the number of endothelial cells circulating in the individual's bloodstream will decrease, thus providing a potential biomarker for gauging the medication's effectiveness. view more (2006-09-18)
Bio-engineering of blood vessels
Blood vessel prostheses work best when the biochemical and mechanical properties match reality as much as possible and when they are made of biodegradable material. To this end tissue technologists grow natural vascular wall cells, endothelial cells, in a biodegradable tube made of collagen. According to Professor Istv'¡n Vermes tissue... view more... (2002-04-16)
A novel mechanism of action for anti-tumor agent, CA4P
Anti-angiogenic agents have been successful in the clinic for blocking the growth of solid tumors. However, these agents used in combination with chemotherapy have improved the survival of patients with cancers by only several months. view more (2005-10-07)
A stem cell type supposed to be crucial for angiogenesis and cancer growth does not exist?
Angiogenesis, the growth of new blood vessels, is a central process in diverse physiological and pathological situations such as healing of wounds and traumas, cardiovascular disorders, inflammatory conditions such as rheumatoid arthritis, and in cancer growth. view more (2008-04-23)
New Developments in Angiogenic Therapy Emerging from Oxford
Angiogenesis, the growth of new blood vessels, is important in the healthy body for healing wounds and, in females, for the monthly reproductive cycle and during pregnancy. It is controlled in the body through the use of the body’s own angiogenesis inhibitors and stimulators. In certain diseases the body is unable to control blood vessel... view more... (2002-08-23)
ABC-transporters expressed on endothelial cell membranes efflux anti-HIV drugs
Researchers at Tulane University Medical Center in New Orleans (USA) have discovered that drug-efflux pumps, belonging to the ATP-binding cassette (ABC) transporter family, are constitutively expressed on vascular endothelial cells. view more (2008-08-27)
New device detects heart disease using less than one drop of blood
Testing people for heart disease might be just a finger prick away thanks to a new credit card-sized device created by a team of researchers from Harvard and Northeastern universities in Boston. view more (2009-06-02)
A few squares of dark chocolate a day may stave off artery hardening in smokers
Dark chocolate may stave off artery hardening in smokers, and a few squares every day could potentially cut the risk of serious heart disease. view more (2005-12-20)
Penn Researchers Unlock Molecular Origin of Blood Stem Cells
A research team led by Nancy Speck, PhD, Professor of Cell and Developmental Biology at the University of Pennsylvania School of Medicine, has identified the location and developmental timeline in which a majority of bone marrow stem cells form in the mouse embryo. view more (2009-01-12)
Vitamin A pushes breast cancer to form blood vessel cells
Researchers at Georgetown University Medical Center have discovered that vitamin A, when applied to breast cancer cells, turns on genes that can push stem cells embedded in a tumor to morph into endothelial cells. These cells can then build blood vessels to link up to the body's blood supply, promoting further tumor growth. view more (2008-07-16)
Mayo Clinic researchers use magnetic attraction to improve stents, reduce blood clot risk
Mayo Clinic heart researchers have devised a new strategy to improve the effectiveness and safety of heart stents, which are used to open narrowed blood vessels and have been the recent subject of clotting concerns. view more (2006-11-03)
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