Endothelial Cells Current Events | Endothelial Cells News | 4
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New study finds key role for VEGF in onset of sepsis
A study led by researchers at Beth Israel Deaconess Medical Center (BIDMC) has found that the vascular endothelial growth factor (VEGF) protein is a key biomarker for sepsis, a severe inflammatory response that develops following a bacterial infection. view more (2006-05-22)
CSHL scientists successfully target tumor microenvironment to stop cancer growth
Cold Spring Harbor Laboratory (CSHL) researchers led by Daniel Nolan and Assistant Professor Vivek Mittal have found that bone marrow (BM) derived endothelial progenitor cells (EPCs) play a critical role in the early stages of tumor progression and that eliminating EPCs stops cancer growth. view more (2007-06-18)
Researchers discover 'sticky' proteins fuse adult stem cells to cardiac muscle, repairing hearts
Cardiologists are increasingly using adult stem cells in clinical trials to repair hearts following heart attacks, but no one has understood how the therapy actually works. view more (2007-02-16)
Spanish fertility experts bring hope of avoiding serious complication of assisted reproduction
Research by Spanish fertility experts is bringing new hope to women of avoiding a serious complication of assisted reproduction - ovarian hyperstimulation syndrome (OHSS)[1]. In its severest form, which requires urgent medical treatment, the syndrome affects around 200 women a year in Spain and as many as 2,000 a year in Europe. OHSS occurs when a... view more... (2003-06-27)
Cytomegalovirus exacerbates atherosclerosis through an autoimmune mechanism
A new study conducted by researchers from the University of Verona and the Institute G. Gaslini in Genova, Italy, confirms the pivotal role played by Cytomegalovirus infection in the pathogenesis of atherosclerosis. view more (2007-05-30)
Model tissue system reveals cellular communication via amino acids
A team of researchers from the Massachusetts General Hospital Center for Engineering in Medicine (MGH-CEM) has found the first evidence of cell-to-cell communication by amino acids, the building blocks of proteins, rather than by known protein signaling agents such as growth factors or cytokines. view more (2009-04-06)
Combination therapy reduces tumor resistance to radiation
Radiation is used to treat a variety of tumors and the response of tumors to radiation is dependent on endothelial cell death, which in turn limits oxygen delivery to the tumor, causing hypoxia and tumor cell death. view more (2007-06-08)
New angiogenesis finding may help fight cancer growth
A researcher at the University of Wisconsin-Madison School of Medicine and Public Health has discovered a new part of the complicated mechanism that governs the formation of blood vessels, or angiogenesis. view more (2006-09-29)
Modified herpes virus keeps arteries 'free-flowing' following procedures
A genetically engineered herpes simplex virus, primarily known for causing cold sores, may help keep arteries "free-flowing" in the weeks following angioplasty or stent placement for patients, according to research published early in the online edition of PNAS (Proceedings of the National Academy of Sciences of the United States of... view more... (2007-07-11)
Dengue and other hemorrhagic fevers: Towards a first potential treatment
Globally, 60 to 100 million people are hit by Dengue, a viral disease transmitted by mosquitoes of the genus Aedes. The most severe form of this disease, which causes blood loss, can lead to a fatal shock-like state (Dengue Shock Syndrome) with or without associated haemorrhage, and is currently increasing in tropical countries. view more (2006-12-26)
Schepens scientists are first to discover angiogenesis switch inside blood vessel cells
Scientists at Schepens Eye Research Institute, an affiliate of Harvard Medical School, are the first to discover a switch inside blood vessel cells that controls angiogenesis (new blood vessel growth). view more (2006-05-19)
Study shows direct link between leptin and obesity-related cardiovascular disease
Obese people who don't have high cholesterol or diabetes might think they're healthy - despite the extra pounds. view more (2008-11-11)
Therapeutic role found for carbon monoxide
In a medical case of Jekyll and Hyde, carbon monoxide - the highly toxic gas emitted from auto exhausts and faulty heating systems - has proven effective in treating the symptoms of pulmonary arterial hypertension (PAH), an extremely debilitating condition that typically leads to right heart failure and eventual death. view more (2006-09-19)
Bone-marrow Cell Transplantation Could Save Limbs (p 427)
Injecting a patient’s bone-marrow cells into their legs could help repair damaged circulatory systems in those with limb ischaemia, suggest authors of a trial in this week’s issue of THE LANCET. Lower limb ischaemia is due to narrowing of the arteries and is a common condition, which if left untreated can lead to gangrene, amputation,... view more... (2002-08-07)
Study identifies another strategy for normalizing tumor blood supply
Manipulating levels of nitric oxide (NO), a gas involved in many biological processes, may improve the disorganized network of blood vessels supplying tumors, potentially improving the effectiveness of radiation and chemotherapy. view more (2008-02-21)
Study reveals a key to blood vessel growth and possible drug target
Researchers have identified a molecular pathway that plays a critical role in the growth of blood vessels. The finding not only offers an important insight into the development of the vascular system during embryonic development but suggests a potential target for inhibiting the blood vessels that fuel cancers, diabetic eye complications and... view more... (2007-10-15)
U of Minnesota researchers find master gene behind blood vessel development
In a first of its kind discovery, University of Minnesota researchers have identified the "master gene" behind blood vessel development. Better understanding of how this gene operates in the early stages of development may help researchers find better treatments for heart disease and cancer. view more (2009-02-05)
Lung damage in babies with congenital heart disease under study
Trying to understand and stop the collateral lung damage that can occur in babies with congenital heart disease is the focus of a new study. view more (2008-03-11)
Importance of preventing congestion in heart failure
Preventing vascular congestion is an important mediator in heart failure, reports a study in the June issue of the Journal of Cardiac Failure published by Elsevier. view more (2009-06-04)
Blood vessel cells are instructed to form tube-like structures
How do blood vessel cells understand that they should organise themselves in tubes and not in layers? A research group from Uppsala University shows for the first time that a special type of "instructor" molecule is needed to accomplish this. These findings, published in the scientific journal Blood, might be an important step towards... view more... (2008-08-29)
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