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Drug therapy reduces neuroblastoma tumor growth in pre-clinical investigation
Researchers from the Children's Cancer Hospital at The University of Texas M. D. Anderson Cancer Center have discovered a new drug combination that significantly hinders tumor growth in neuroblastoma, a childhood cancer. view more (2009-04-27)
Novel findings about neovessel formation
The main role in new findings about neovessel formation is played by a protein called tissue factor. This factor turns out to have both a stimulatory function and an inhibitory function in the generation of blood vessels. Normally these two functions neutralize each other, but in diseases like retinopathy - where unwanted blood vessels grow into... view more... (2004-05-10)
Venous origin of the mammalian lymphatic vasculature
In the October 1 issue of G&D, Dr. Guillermo Oliver (St. Jude Children's Research Hospital) and colleagues present new evidence to resolve a century-old debate over the origin of the mammalian lymphatic vasculature. view more (2007-10-01)
Farnesoid X receptor regulates cystathionase
The expression and activity of Cystathionase is reduced in rodent models of liver injury, leading to hyper-homocysteinemia and impaired generation of hydrogen sulphide, two factors that contribute to endothelial dysfunction and increased intrahepatic resistance. view more (2009-05-13)
Stem Cells from Hair Follicles May Help
For a rich source of stem cells to be engineered into new blood vessels or skin tissue, clinicians may one day look no further than the hair on their patients' heads, according to new research published earlier this month by University at Buffalo engineers. view more (2008-03-31)
Stunning finding: Compounds protect against cerebral palsy
Two compounds developed by Northwestern University chemists have been shown to be effective in pre-clinical trials in protecting against cerebral palsy, a condition caused by neurodegeneration that affects body movement and muscle coordination. view more (2009-02-25)
Experimental anti-cancer synthetic molecule targets tumor cell growth and angiogenesis
A recent study conducted by three French CNRS (Centre National de la Recherche Scientifique) laboratories describes a new candidate anti-cancer drug, named HB-19. view more (2008-06-18)
New light shed on the enigma of salt intake and hypertension
A high salt intake has been implicated in cardiovascular disease risk for 5000 years. But salt-sensitive hypertension still remains an enigma. view more (2009-05-04)
A consistent decline in heart attack rates following the implementation of smoking bans
Strongly enforced legislation to restrict smoking produces rapid and substantial reductions in community rates of heart attack, according to a meta-analysis published today in Circulation, the journal of the American Heart Association. view more (2009-09-22)
Elevated biomarkers predict risk for prostate cancer recurrence
A simple blood test screening for a panel of biomarkers can accurately predict whether a patient who has had prostate cancer surgery will have a recurrence or spread of the disease. view more (2008-06-26)
Stem cells in adult testes provide alternative to embryonic stem cells for organ regeneration
Easily accessed and plentiful, adult stem cells found in a male patient's testicles might someday be used to create a wide range of tissue types to help him fight disease -- getting around the need for more controversial embryonic stem cells. view more (2007-09-20)
Angiogenesis linked to poor survival in patients with rare type of ovarian cancer
Researchers from The University of Texas M. D. Anderson Cancer Center have found that increased angiogenesis, or blood vessel formation, and vascular endothelial growth factor expression are associated with poor survival in women with sex cord-stromal ovarian tumors. view more (2009-02-06)
Value of stent-coating drugs questioned
Patients admitted to the hospital with acute coronary syndromes (ACS) are often treated with a catheter-based procedure known as percutaneous coronary intervention (PCI), during which a stent is inserted into an occluded or narrowed coronary artery to restore blood flow to and from the heart. view more (2007-03-27)
Researchers grow human blood vessels in mice from adult progenitor cells
For the first time, researchers have successfully grown functional human blood vessels in mice using cells from adult human donors - an important step in developing clinical strategies to grow tissue, researchers report in Circulation Research: Journal of the American Heart Association. view more (2008-07-21)
New Stem Cell Program : Funds Awarded to Nervous System Projects and Stem Cell Bank Networks
Nine projects and two extensive networks will share 44 million Swedish kronor (SEK) in research funds, the first grants awarded by Sweden's new Joint Program on Stem Cell Research. Of nearly 50 applicants, 11 received grants. Several of the funded projects address the nervous system. Diabetes is another area to receive funding. - The entire stem... view more... (2002-09-05)
A breath of fresh air could improve drug toxicity screening
A team led by Massachusetts General Hospital (MGH) researchers has developed an innovative way to culture liver cells for drug toxicity screening. view more (2009-09-03)
A fisheye view of the deadliest breast cancer
Inflammatory breast cancer (IBC) is the deadliest form of the disease, with fewer than half of those diagnosed today having a five-year prognosis for survival. view more (2006-12-13)
A type of antioxidant may not be as safe as once thought
Certain preparations taken to enhance athletic performance or stave off disease contain an anti-oxidant that could cause harm. view more (2007-09-05)
The First EVGN Annual Conference: Scientists Describe A Potential Vaccine Against Heart Disease
What is the relationship between atherosclerosis and the immune response and what are the possibilities for the development of a vaccine against cardiovascular disease? What role do stem cells play in angiogenesis and what are the possible clinical applications of stems cells in cardiac recovery? view more (2004-12-13)
Pulmonary hypertension in children may result from reduced activity of gene regulator
Too little activity by gene regulators called PPARs appears to be a major player in the irreversible lung damage that can occur in children with heart defects, researchers say. view more (2009-03-06)
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