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Key process in gene regulation occurs in blood platelets, Univeristy of Utah researchers find
In a discovery that upends a longstanding tenet of human biology, University of Utah School of Medicine researchers have shown that a key process in gene regulation can occur in human platelets, unique cells that are unusual because they don't have a nucleus (anucleate). view more (2005-08-12)
Contribution of cholesterol transporter to vascular disease
Low-density lipoprotein (LDL), a transporter of cholesterol, may also contribute to vascular diseases by a previously unidentified mechanism, according to a report published online this week in EMBO reports. view more (2007-10-26)
Gap junction protein vital to successful pregnancy, researchers find
Researchers studying a critical stage of pregnancy - implantation of the embryo in the uterus - have found a protein that is vital to the growth of new blood vessels that sustain the embryo. Without this protein, which is produced in higher quantities in the presence of estrogen, the embryo is unlikely to survive. view more (2008-09-11)
Malignant melanoma cells secrete protein required for embryo formation
A Northwestern University research group has discovered that aggressive melanoma cells secrete Nodal, a protein that is critical to proper embryo formation. view more (2006-07-31)
UK researcher finds 'switching' compound for angiogenesis
For the second time in a week Dr. Jayakrishna Ambati, UK HealthCare physician and associate professor and vice chair of the Department of Ophthalmology and Visual Sciences, announced a discovery from his lab that will affect the future of macular degeneration treatment and research. view more (2006-02-03)
Damaged veins heal faster with heparin treatment, laboratory study finds
A commonly used medication that prevents blood clots from forming may also prevent existing clots from damaging delicate vein walls - and may accelerate healing in a clot-damaged area of vein wall, according to new research from the University of Michigan Cardiovascular Center. view more (2008-03-14)
Stanford doctors advance in bid to turn mice stem cells into blood vessels
Researchers at the Stanford University School of Medicine have taken a first step toward growing blood vessels from stem cells that could eventually be transplanted into living organisms. view more (2006-06-22)
New drug substantially extends survival in pancreatic cancer
A new form of chemotherapy that destroys new blood vessels that grow around tumors has produced excellent results in a phase II trial of patients with inoperable pancreatic cancer, researchers report at the 33rd Congress of the European Society for Medical Oncology (ESMO) in Stockholm. view more (2008-09-17)
A new significance of LVD and angiogenic MVD is identified in human primary SCRC
Lymphangiogenesis and angiogenesis are critical processes for tumor growth, invasion and metastasis. Angiogenesis has established its role in the development and progression of a variety of malignancies, playing a crucial role in the dissemination of the tumor cells. view more (2008-01-17)
Key mechanism found that promotes spread of malignant melanoma
Researchers at Northwestern University have discovered a key signaling mechanism that may promote the ability of highly aggressive malignant melanoma cells to metastasize, or spread from a primary tumor to distant sites within the body. view more (2005-11-01)
GEN reports on strategies to overcome blood-brain barrier
The blood-brain barrier (BBB) remains a major obstacle to the successful delivery of drugs to treat central nervous system (CNS) disorders, reports Genetic Engineering and Biotechnology News (GEN). view more (2009-02-06)
Biomarkers predict brain tumor's response to therapy
A report in Cancer Research, a journal of the American Association for Cancer Research, highlights a new biomarker that may be useful in identifying patients with recurrent glioblastoma, or brain tumors, who would respond better to anti-vascular endothelial growth factor therapy, specifically cediranib. view more (2009-06-24)
New study shows Concord grape juice has a heart-healthy effect not yet reported with red wine
Many studies have suggested that moderate red wine consumption is beneficial to cardiovascular health. But what if you'd like to skip the alcohol? view more (2007-10-03)
Carbon monoxide protects lung cells against oxygen-induced damage
Researchers at the University of Pittsburgh have demonstrated that low-dose carbon monoxide administered in conjunction with oxygen therapy markedly inhibits oxygen-induced damage to lung cells. view more (2007-01-19)
Molecule prompts damaged heart cells to repair themselves after a heart attack
A protein that the heart produces during its early development reactivates the embryonic coronary developmental program and initiates migration of heart cells and blood vessel growth after a heart attack, researchers at UT Southwestern Medical Center have found. view more (2009-04-13)
Marijuana component opens the door for virus that causes Kaposi's sarcoma
The major active component of marijuana could enhance the ability of the virus that causes Kaposi's sarcoma to infect cells and multiply. view more (2007-08-02)
Air pollution link to clogged arteries
Should we be watching our exposure to airborne pollution as well as our cholesterol levels" Research now indicates that air pollution has a role to play in atherosclerosis (artery hardening), which can contribute to heart attacks or strokes. view more (2007-07-26)
Nanoparticles can track cells deep within living organisms
To the delight of researchers at Washington University School of Medicine in St. Louis, living cells gobbled up fluorine-laced nanoparticles without needing any coaxing. Then, because of the unusual meal, the cells were easily located with MRI scanning after being injected into mice. view more (2007-03-27)
The future of personalized cancer treatment: An entirely new direction for RNAi delivery
In technology that promises to one day allow drug delivery to be tailored to an individual patient and a particular cancer tumor, researchers at the University of California, San Diego School of Medicine, have developed an efficient system for delivering siRNA into primary cells. view more (2009-05-18)
Could skin cells become brain cells? (p 172)
Results of an experimental study in this week's issue of THE LANCET highlight how adult skin cells can be made into precursor nerve cells, with potential implications for the future treatment of neurodegenerative disorders such as Parkinson's disease. Ethical and practical considerations limit the availability of neural stem cells derived from... view more... (2004-07-07)
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