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Leading cause of death in 'preemies' might be controlled by resetting a molecular switch
Blocking signals from a key molecular receptor that normally switches on the intestine's immune response but instead becomes too intense in the presence of stress and toxins may help reverse necrotizing enterocolitis (NEC), a leading cause of death in premature newborns. view more (2007-12-03)
Children's Hospital researchers identify molecular 'switch' that could save very young lives
A team of researchers at Children's Hospital of Pittsburgh of UPMC have identified a molecular "switch" that, when blocked, may help reverse necrotizing enterocolitis (NEC), a leading cause of death in premature infants. view more (2007-12-05)
The road to allergy
A UK scientist has discovered the route and type of transport taken by peanut proteins through the gut to the immune system. This route favours an immune response, which helps explain why peanuts are one of the most allergenic foods. view more (2004-11-18)
Similar stem cells in insect and human gut
Scientists at the Carnegie Institution's Department of Embryology have found that adult fruitflies have the same stem cells controlling cell regulation in their gut as humans do. view more (2005-12-08)
Cholesterol modulates sorting of CEA -- implications for inflammatory bowel disease
In polarized Caco-2 cells, cholesterol was depleted by a combination of synthesis inhibition and plasma membrane extraction with complexing agents. view more (2008-04-30)
After a 40-year search, a hormone controlling iron metabolism in mammals is finally identified
Iron is vital for cells, because it catalyzes key enzyme reactions; it is also crucial for respiration, fixing atmospheric oxygen to hemoglobin in red blood cells. Iron deficiency can lead to severe anemia, with inadequate tissue oxygenation. An excess of iron is also toxic, as it facilitates the... view more (2002-04-03)
UB Scientist Discovers Novel Iron-Copper Alliance
Iron is the workhorse of trace minerals. An essential component of red blood cells, disruption of iron levels in the body will result in a myriad of serious conditions, and life cannot be sustained without it. view more (2007-07-24)
Listeria monocytogenes: how can a relatively innocuous food-borne pathogen induce a potentially fatal disease?
Listeria monocytogenes (L. monocytogenes) provokes listeriosis, a potentially fatal food-borne disease, which mainly affects pregnant women and immuno-compromised individuals where it can lead to death rate as high as 30%. Understanding the mechanism behind the disease is crucial to dealing with... view more (2004-04-20)
Colon Cancer : An alternative pathway of tumor development
Cancer develops from a single damaged cell subsequent to an accumulation of genetic errors in a number of its genes. The nature of these alterations and the order in which they occur differ from one cancer to another : hence, the "pathways" that may lead to cancer are numerous. CNRS and... view more (2002-09-13)
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