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Sugar-coated antibiotics
Researchers from the John Innes Centre and the University of East Anglia have recently elucidated the structure and function of an enzyme which is involved in decorating antibiotics with sugar molecules.   view more (2008-05-29)

Enzyme promotes fat formation
The enzyme TPPII may contribute to obesity by stimulating the formation of fat cells, suggests a study in EMBO reports this week. The enzyme, TPPII, has previously been linked to making people feel hungry, but Jonathan Graff and colleagues now show that it may be even more deeply involved in... view more (2007-10-12)

The secret behind silkworm's hardy stomachs
Silkworms have a unique ability to eat toxic mulberry leaves without feeling ill, and researchers have come one step closer to understanding why: silkworms contain a special digestive enzyme that is not affected by mulberry's toxic chemicals.   view more (2008-05-28)

UAB research could improve the prognosis and treatment of lung cancer
A group of scientists led by Professor Xavier Parés of the Department of Biochemistry and Molecular Biology at Universitat Autònoma de Barcelona, has published a research on AKR1B10, an enzyme that is detected in large quantities only in lung cancers, particularly those caused by... view more (2008-01-08)

The structure of resistance
A team of scientists from the University Paris Descartes has solved the structure of two proteins that allow bacteria to gain resistance to multiple types of antibiotics, according to a report in EMBO reports this month.   view more (2008-02-25)

Gene-regulating enzyme is also a target for anti-depressive drugs
In 2005, professor Ramin Shiekhattar, Ph.D., at The Wistar Institute and his colleagues reported details about an enzyme involved in appropriately repressing sets of neuronal genes in non-neuronal cells.   view more (2006-06-26)

Convincing results: Stopping the spread of cancer in the body
A team of Danish researchers have discovered that by blocking a specific enzyme, it is possible to check the spread of cancer in the body. This finding may be the first step towards preventing deaths due to cancer spreading to other parts of the body. The discovery may also help reduce the amount... view more (2004-11-22)

Discovery of new protein could provide new understanding of male fertility
Scientists have discovered a new enzyme involved in the degradation of proteins inside cells, a process that helps eliminate or recycle proteins that are no longer needed.   view more (2007-08-03)

Worth a thousand words: Hopkins researchers paint picture of cancer-promoting culprit
They say that a picture can be worth a thousand words. This especially is true for describing the structures of molecules that function to promote cancer. Researchers at Johns Hopkins have built a three-dimensional picture of an enzyme often mutated in many types of cancers.   view more (2008-01-07)

New inhibitor has potential as cancer drug
Laboratory experiments have previously shown that cancer cells overproduce an enzyme, heparanase, which splits the body's own polysaccharide heparan sulfate into shorter fragments.   view more (2007-10-23)

Enzyme discovery sheds light on vitamin D
Surprising findings by Queen's researchers have shed new light on how the "sunshine vitamin" D - increasingly used to treat and prevent cancer and other diseases - is broken down by our bodies.   view more (2007-07-25)

Opening and closing the genome
At any given time, most of the roughly 30,000 genes that constitute the human genome are inactive, or repressed, closed to the cellular machinery that transcribes genes into the proteins of the body.   view more (2007-02-26)

Success for fishy scientist
Scallops, oysters and mussels - the best of fare Scotland`s kitchens have resulted in a top Parisian award for a researcher from the University of Dundee. Matthew Gubbins is not a chef but a scientific expert on toxicity in shellfish. Matthew (26) has scooped the Daniel Jouvance award for his work... view more (2002-07-18)

Unlocking the function of enzymes
Fitting a key into a lock may seem like a simple task, but researchers at Texas A&M University are using a method that involves testing thousands of keys to unlock the functions of enzymes, and their findings could open the door for new targets for drug designs.   view more (2007-11-07)

Towards the mechanism of cell respiration
Researchers at the Institute of Biotechnology of the University of Helsinki have for the first time identified an internal electron transfer reaction that initiates the proton pump mechanism of the respiratory enzyme.   view more (2006-04-06)

Treatment discovered for deadly childhood disease
Researchers have discovered that a treatment involving enzyme replacement therapy dramatically reduces the risk of death in children with Pompe disease, a rare genetic disorder in which most children die before their first birthday.   view more (2006-12-07)

Catalyst mystery unlocked
Different keys are not supposed to fit the same lock, but in biological systems multiple versions of a catalyst all make a reaction go, according to a new study that explains the phenomenon.   view more (2008-08-19)

Researcher working on destruction of chemical weapons
America's war on terror includes fighting the dark side of deadly chemical agents, and Texas A&M University chemist Dr. Frank Raushel is helping with the fight by developing an enzyme that might neutralize one such chemical agent, the organophosphates.   view more (2008-09-25)

Molds for Molecules
Molecular imprints in polymers as reaction vessels for pharmaceuticals research Materials with the tiniest of cavities, which can take up other molecules as "guests", play a meaningful role in science and technology. A particularly interesting process for the synthesis of materials with precisely... view more (2002-11-28)

Newly discovered molecule promises better treatments for heart attacks, heart surgery
Scientists have discovered a compound that could lead to new treatments for heart attacks as well as methods to protect hearts during open heart surgery and other situations in which blood flow to the heart is interrupted.   view more (2008-09-12)

Structure of key enzyme in plague bacterium found
Researchers at the National Institute of Standards and Technology (NIST) have solved the structure of a key enzyme from the bacterium responsible for plague, finding that it has a highly unusual configuration. The results may shed light both on how the bacterium kills and on fundamental cell... view more (2006-08-21)

Rutgers researchers find fat gene
Rutgers researchers have identified a gene - and the molecular function of its protein product - that provides an important clue to further understanding obesity and may point the way to new drugs to control fat metabolism.   view more (2006-03-21)

Study shows vitamin C is essential for plant growth
Scientists from the University of Exeter and Shimane University in Japan have proved for the first time that vitamin C is essential for plant growth. This discovery could have implications for agriculture and for the production of vitamin C dietary supplements.   view more (2007-09-24)

Enzyme defect leads to hyperinsulinism
A recent study in the Journal of Biological Chemistry confirms that mutations in an enzyme called glutamate dehydrogenase can cause congenital hyperinsulinism.   view more (2006-05-25)

Computers worldwide speed search for anti-smallpox drugs
A major computer project has been launched today to analyse millions of different chemicals in the search for drugs to combat the bioterrorist threat of smallpox. The smallpox research project will use the 'screensaver downtime' donated by up to two million computer users worldwide to screen 35... view more (2003-02-04)
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