Enzyme Complex Current Events | Enzyme Complex News
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SUMO protein guides chromatin remodeler to suppress genes
In an in vitro study, led by Grace Gill, PhD, Tufts University School of Medicine, researchers discovered how a protein called SUMO (Small Ubiquitin-related Modifier) guides an enzyme complex that alters the structure of chromatin to regulate expression of genes. view more (2009-04-28)
Gene-regulating enzyme is also a target for anti-depressive drugs
In 2005, professor Ramin Shiekhattar, Ph.D., at The Wistar Institute and his colleagues reported details about an enzyme involved in appropriately repressing sets of neuronal genes in non-neuronal cells. view more (2006-06-26)
Molecular partners required for appropriate neuronal gene repression
In their efforts to understand the complex biology of life, scientists often seek to isolate individual elements of the puzzle for study, to break the problem down to a more manageable size. Single genes and molecules are closely analyzed to better understand their specific interactions with other single entities within larger systems. view more (2005-08-04)
Penn researchers determine structure of smallpox virus protein bound to DNA
Researchers at the University of Pennsylvania School of Medicine have determined the structure of an important smallpox virus enzyme and how it binds to DNA. view more (2006-08-07)
Starve a yeast, sweeten its lifespan
Johns Hopkins researchers have discovered a new energy-making biochemical twist in determining the lifespan of yeast cells, one so valuable to longevity that it is likely to also functions in humans. view more (2009-03-24)
New Piece Found in the Puzzle of Epigenetics
A team of scientists led by Professor Dirk Eick of Helmholtz Zentrum München has identified the enzyme TFIIH kinase as an important factor in the epigenetic regulation of the cell nucleus enzyme RNA polymerase II. view more (2009-06-17)
Sugar-coated antibiotics
Researchers from the John Innes Centre and the University of East Anglia have recently elucidated the structure and function of an enzyme which is involved in decorating antibiotics with sugar molecules. view more (2008-05-29)
How an enzyme tells stem cells which way to divide
Driving Miranda, a protein in fruit flies crucial to switch a stem cell's fate, is not as complex as biologists thought, according to University of Oregon biochemists. They've found that one enzyme (aPKC) stands alone and acts as a traffic cop that directs which roads daughter cells will take. view more (2009-05-14)
Structure of important neurotransmitter regulator determined
Researchers from Virginia Tech and the Brookhaven National Laboratory have solved the structure of an enzyme that is critical in the regulation of the neurotransmitter system in the human brain. view more (2008-02-04)
Enzyme promotes fat formation
The enzyme TPPII may contribute to obesity by stimulating the formation of fat cells, suggests a study in EMBO reports this week. The enzyme, TPPII, has previously been linked to making people feel hungry, but Jonathan Graff and colleagues now show that it may be even more deeply involved in causing obesity. view more (2007-10-12)
Treatment discovered for deadly childhood disease
Researchers have discovered that a treatment involving enzyme replacement therapy dramatically reduces the risk of death in children with Pompe disease, a rare genetic disorder in which most children die before their first birthday. view more (2006-12-07)
Night of the living enzyme
Inactive enzymes entombed in tiny honeycomb-shaped holes in silica can spring to life, scientists at the Department of Energy's Pacific Northwest National Laboratory have found. view more (2006-11-29)
Opening and closing the genome
At any given time, most of the roughly 30,000 genes that constitute the human genome are inactive, or repressed, closed to the cellular machinery that transcribes genes into the proteins of the body. view more (2007-02-26)
Study details structural changes of a key catalytic enzyme
Enzymes are complex proteins capable of catalyzing specific biochemical reactions in cells. view more (2006-09-21)
The secret behind silkworm's hardy stomachs
Silkworms have a unique ability to eat toxic mulberry leaves without feeling ill, and researchers have come one step closer to understanding why: silkworms contain a special digestive enzyme that is not affected by mulberry's toxic chemicals. view more (2008-05-28)
Scientists demonstrate feasibility of preventing malaria parasite from becoming sexually mature
Researchers have demonstrated the possibility of preventing the human malaria parasite, Plasmodium falciparum, which is responsible for more than a million malaria deaths a year, from becoming sexually mature. view more (2008-06-03)
UAB research could improve the prognosis and treatment of lung cancer
A group of scientists led by Professor Xavier Parés of the Department of Biochemistry and Molecular Biology at Universitat Autònoma de Barcelona, has published a research on AKR1B10, an enzyme that is detected in large quantities only in lung cancers, particularly those caused by smoking. view more (2008-01-08)
UCLA physicists report advance toward nanotechy approach to protein engineering
UCLA physicists report a significant step toward a new approach to protein engineering in the June 8 online edition, and in the July print issue, of the Journal of the American Chemical Society. view more (2006-06-12)
Groundbreaking study on complex movements of enzymes
A groundbreaking study has revealed in great detail how enzymes in the cell cooperate to make fat. These enzymes are integrated into a single molecular complex known as fatty acid synthase. This complex is regarded as a potential target for developing new anti-obesity and anti-cancer drugs. view more (2009-02-12)
Gene variant linked to risk of stroke and heart attack for those on Plavix
A new study reports that a gene variant carried by about a third of the population plays a major role in this group's response to an anti-clotting medicine, clopidogrel (Plavix). People with the variant produce a defective version of the CYP2C19 enzyme and are less able to activate the drug. view more (2009-08-26)
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