Enzyme Inhibitor Current Events | Enzyme Inhibitor News | 2
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Blood pressure drugs associated with reduced risk of esophageal, pancreatic and colon cancers
Thousands of individuals currently taking angiotension converting enzyme (ACE) inhibitors, a type of medication commonly used to lower blood pressure, may be doing more than treating their hypertension. view more (2006-05-24)
Research could lead to treatment for Alzheimer's disease
A molecule designed by a Purdue University researcher could lead to the first drug treatment for Alzheimer's disease. view more (2007-04-19)
Flesh-eating bacteria escape body's safety net
Researchers at the University of California, San Diego (UCSD) School of Medicine have discovered that so-called flesh-eating "Strep" bacteria use a specific enzyme to break free of the body's immune system, a finding which could potentially lead to new treatments for serious infections in human patients. view more (2006-02-21)
HIV integrase inhibitor effective for patients beginning antiretroviral treatment
A member of a new class of antiretroviral drugs is safe and effective for patients beginning treatment against HIV, according to researchers who have completed a two-year multisite phase III clinical trial comparing it with standard antiretroviral drugs. view more (2009-08-03)
Study finds HIV protease inhibitor drugs may adversely affect the scaffolding of the cell nucleus
UCLA scientists, along with collaborators from Purdue University, have demonstrated that HIV protease inhibitors - crucial drugs for HIV treatment - block a cellular enzyme important for generating the structural scaffolding for the cell nucleus. view more (2007-07-17)
Enzyme inhibitors block replication Of SARS virus
Researchers have known since 2003 that a site on the virus is responsible for mediating proteases that allow the virus to replicate. Since then researchers have been testing protease inhibitors to lock up this site, known as SARS 3CLpro, and effectively stop the virus from infecting additional cells in the body. view more (2006-03-28)
Scientists design potent anthrax toxin inhibitor
Scientists funded by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), have engineered a powerful inhibitor of anthrax toxin that worked well in small-scale animal tests. view more (2006-04-25)
Study provides clues to prevent spread of ovarian cancer
A drug that blocks production of an enzyme that enables ovarian cancer to gain a foothold in a new site can slow the spread of the disease and prolong survival in mice, according to a study by researchers from the University of Chicago Medical Center, but only if the drug is given early in the disease process. view more (2008-03-14)
Anthrax inhibitor counteracts toxin, may lead to new therapeutics
Researchers from Rensselaer Polytechnic Institute and the University of Toronto have designed a nanoscale assembly of molecules that successfully counteracts and inhibits anthrax toxin in animal and laboratory experiments. view more (2006-04-24)
COX-2 inhibitor could be safest anti-inflammatory drug for older people (p 1751)
A Canadian study involving over 130,000 older people in this week's issue of THE LANCET shows how the anti-inflammatory cyclo-oxygenase-2 (COX-2) inhibitor celecoxib may have a lower risk of congestive heart failure compared with other non-steroidal anti-inflammatory drugs. Non-selective, non-steroidal anti-inflammatory drugs (NSAIDs) are... view more... (2004-05-26)
Sugar-coated antibiotics
Researchers from the John Innes Centre and the University of East Anglia have recently elucidated the structure and function of an enzyme which is involved in decorating antibiotics with sugar molecules. view more (2008-05-29)
Pest control research leads to pain control discovery
A newly discovered enzyme inhibitor, identified by researchers originally looking for biological pest controls, may lead to pain relief for sufferers of arthritis and other inflammatory diseases. view more (2006-08-29)
New cancer drug hope
Scientists helping to develop the next generation of cancer-beating drugs say they have had a major breakthrough with their latest results. view more (2006-10-27)
Gaining Ground in the Race Against Antibiotic Resistance
Antibiotic resistance has put humans in an escalating 'arms race' with infectious bacteria, as scientists try to develop new antibiotics faster than the bacteria can evolve new resistance strategies. view more (2005-09-20)
Novel enzyme inhibitor paves way for new cancer drug
Combining natural organic atoms with metal complexes, scientists at The Wistar Institute have developed a new type of enzyme inhibitor capable of blocking a biochemical pathway that plays a key role in cancer development. view more (2008-05-16)
Enzyme may hold key to new treatment of diabetic kidney disease
Northwestern University Feinberg School of Medicine researchers have found that an enzyme called ACE2 may hold the potential to treat diabetic kidney disease, the most common form of kidney disease. view more (2006-11-08)
Enzyme Structure Reveals New Drug Targets for Cancer and Other Diseases
If the genome is the parts list of the human cell, certain proteins are the production managers, activating and deactivating genes as needed. Scientists funded by the National Institute of General Medical Sciences (NIGMS), part of the National Institutes of Health, now have a clearer understanding of how a key protein controls gene activity and... view more... (2008-02-15)
Common Ancestry of Bacterium and Plants Could be Key to an Effective New Treatment for Chlamydia
Rutgers researchers have discovered that the Chlamydia bacterium, which causes a sexually transmitted disease (STD), shares an evolutionary heritage with plants. view more (2006-11-08)
Could new discovery about a shape-shifting protein lead to a mighty 'morpheein' bacteria fighter?
A small molecule that locks an essential enzyme in an inactive form could one day form the basis of a new class of unbeatable, species-specific antibiotics, according to researchers at Fox Chase Cancer Center. view more (2008-06-23)
New potential therapeutic target discovered for genetic disorder -- Barth syndrome
Researchers at NYU Langone Medical Center may have discovered a new targeted intervention for Barth Syndrome (BTHS). BTHS, a sometimes fatal disease, is a serious genetic disorder occurring predominantly in males that leads to infection or heart failure in childhood. view more (2009-03-03)
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