Enzyme Inhibitor Current Events | Enzyme Inhibitor News | 5
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Ireland Cancer Center researcher lays out benefits of aspirin to prevent colon cancer
A colon cancer researcher at the Ireland Cancer Center of University Hospitals Case Medical Center (UHCMC) has laid out the roadmap for how medical science should employ aspirin and new aspirin-like drugs for use in preventing colon cancer in certain high-risk individuals. view more (2007-05-24)
Compound reveals new link between signaling protein and cell migration
University of Illinois at Chicago researchers report that a protein that regulates key signaling pathways in cells also plays a role in controlling the active movement or migration of cells. view more (2005-09-26)
Enzyme discovery sheds light on vitamin D
Surprising findings by Queen's researchers have shed new light on how the "sunshine vitamin" D - increasingly used to treat and prevent cancer and other diseases - is broken down by our bodies. view more (2007-07-25)
ESC Congress 2004: First long-term comparative study of an ARB and an ACE inhibitor in patient with type 2 diabetes, hypertension and early nephropathy
Results from the first long-term comparative study of an angiotensin receptor blocker (ARB) and an ACE inhibitor in patients with type 2 diabetes, hypertension and early nephropathy were presented today.1 The five year DETAIL (Diabetics Exposed to Telmisartan And enalaprIL) study showed that telmisartan provides comparable renoprotective effects... view more... (2004-08-31)
Ace Inhibitors Could Slow Muscle Decline (p 926)
Angiotensin-converting enzyme (ACE) inhibitors, a class of drugs used to lower blood pressure, could also be protective against the decline in muscle strength in elderly women suggest authors of a study in this week's issue of THE LANCET. ACE inhibitors are known to prevent the decline in physical function in patients with congestive heart failure... view more... (2002-03-13)
Licorice compound offers new cancer prevention strategy
A chemical component of licorice may offer a new approach to preventing colorectal cancer without the adverse side effects of other preventive therapies, Vanderbilt University Medical Center researchers report. view more (2009-03-24)
New insight into the controls on a go-to enzyme
Scientists at St. Jude Children's Research Hospital have gained new insights into regulation of one of the body's enzyme workhorses called calpains. view more (2008-11-20)
Enzyme doesn't act alone in atrial fibrillation
An overactive enzyme is behind a leaky calcium channel that plays a role in the development of atrial fibrillation, which is the most common cardiac arrhythmia that is responsible for a third of all strokes. view more (2009-06-18)
Curacyte scientists discover new anti-tumour agents
Curacyte AG, a Munich-based drug development company focused on novel treatments of inflammatory diseases, thrombotic disorders and cancer has announced today that its scientists have discovered a series of novel small molecule inhibitors of matriptase, a trypsin-like serine protease. Matriptase is an important mediator in the degradation of the... view more... (2003-06-17)
Opening and closing the genome
At any given time, most of the roughly 30,000 genes that constitute the human genome are inactive, or repressed, closed to the cellular machinery that transcribes genes into the proteins of the body. view more (2007-02-26)
Success for fishy scientist
Scallops, oysters and mussels - the best of fare Scotland`s kitchens have resulted in a top Parisian award for a researcher from the University of Dundee. Matthew Gubbins is not a chef but a scientific expert on toxicity in shellfish. Matthew (26) has scooped the Daniel Jouvance award for his work on how shellfish become toxic and then lose their... view more... (2002-07-18)
Gardenia fruit compound starting point for diabetes therapy
A Gardenia fruit extract traditionally used in Chinese medicine to treat the symptoms of type 2 diabetes does indeed contain a chemical that reverses some of the pancreatic dysfunctions that underlie the disease. view more (2006-06-07)
Unlocking the function of enzymes
Fitting a key into a lock may seem like a simple task, but researchers at Texas A&M University are using a method that involves testing thousands of keys to unlock the functions of enzymes, and their findings could open the door for new targets for drug designs. view more (2007-11-07)
Risk of abnormally slow heart rate twice as high in those taking drugs to slow Alzheimer's
People taking one of several drugs commonly prescribed to treat Alzheimer's disease are more likely to be hospitalized for a potentially serious condition called bradycardia than patients not taking these medications. view more (2009-10-02)
Towards the mechanism of cell respiration
Researchers at the Institute of Biotechnology of the University of Helsinki have for the first time identified an internal electron transfer reaction that initiates the proton pump mechanism of the respiratory enzyme. view more (2006-04-06)
New information points to safer methadone use for treatment of pain and addiction
New findings may significantly improve the safety of methadone, a drug widely used to treat cancer pain and addiction to heroin and other opioid drugs, according to researchers at Washington University School of Medicine in St. Louis and the University of Washington in Seattle. view more (2009-03-03)
Low-dose chemotherapy plus antiangiogenesis drug has activity in advanced breast cancer
Chemotherapy given in low, frequent doses - a novel strategy called "metronomic" delivery - achieved partial shrinkage of disease in some advanced breast cancer patients when given concurrently with an angiogenesis inhibitor. view more (2005-12-09)
Treatment discovered for deadly childhood disease
Researchers have discovered that a treatment involving enzyme replacement therapy dramatically reduces the risk of death in children with Pompe disease, a rare genetic disorder in which most children die before their first birthday. view more (2006-12-07)
Most Cardiologists Believe That LDL Cholesterol Should Be Lowered
Beyond Current Guidelines for Patients with Risk Factors, Reveals New Pan-European Survey view more (2004-08-31)
Researchers track down the genes that could put the brakes on breast cancer.
Normally, old or damaged cells are told to stop dividing and 'self-destruct' to prevent any mutations being duplicated and growing into tumours. But cancer cells usually ignore these messages and become 'immortal' allowing them to continue multiplying indefinitely and out of control. Scientists already know that an enzyme called 'telomerase' is... view more... (1999-02-22)
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