Enzyme Inhibitor Current Events | Enzyme Inhibitor News | 8
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Affibody ligands to Finnzymes
Affibody AB and Finnzymes Oy today announce that they have established a collaboration. The scope of the collaboration is to develop Affibody® affinity ligands for use in amplification of genetic material. Under the agreement, Affibody will develop specific affinity ligands, Affibody® molecules, to be used in kits for HotStart polymerase... view more... (2004-03-24)
Penn researchers determine structure of smallpox virus protein bound to DNA
Researchers at the University of Pennsylvania School of Medicine have determined the structure of an important smallpox virus enzyme and how it binds to DNA. view more (2006-08-07)
Cellular self-eating promotes pancreatitis
To survive tough times, cells sometimes resort to a form of self-cannibalism called autophagy. But as Hashimoto et al. reveal, autophagy can have a down side, destroying the pancreas by prematurely activating a digestive enzyme. view more (2008-06-30)
Compounds could be new class of cancer drugs
A team of Vanderbilt University Medical Center investigators has developed a group of chemical compounds that could represent a new class of drugs for treating cancer. view more (2009-02-04)
Genetic Testing For Cell-Proliferation Enzyme Could Improve Treatment Of Acute Lymphoblastic Leukaemia (p 1033)
Authors of a Canadian research letter in this week's issue of THE LANCET describe how genetic testing for an enzyme involved in cancer-cell proliferation could identify patients at an increased risk of poor outcome from acute lymphoblastic leukaemia. The enzyme thymidylate synthase is associated with cell proliferation, and is therefore an... view more... (2002-03-20)
Neutrophils in rheumatoid arthritis: How to lessen inflammation but still fight infection
Neutrophils, which quickly congregate at the sites of infection and inflammation, are capable of ingesting microorganisms or other particles. view more (2006-06-16)
UT Southwestern: Killing bacteria isn't enough to restore immune function after infection
A bacterial molecule that initially signals to animals that they have been invaded must be wiped out by a special enzyme before an infected animal can regain full health, researchers at UT Southwestern Medical Center have found. view more (2008-09-11)
Hopkins researchers discover new link to schizophrenia
Neuroscientists at Johns Hopkins have discovered that mice lacking an enzyme that contributes to Alzheimer disease exhibit a number of schizophrenia-like behaviors. view more (2008-05-09)
Cow stomach holds key to turning corn into biofuel
An enzyme from a microbe that lives inside a cow's stomach is the key to turning corn plants into fuel, according to Michigan State University scientists. view more (2008-04-08)
Duke team finds compounds that prevent nerve damage
Duke University Medical Center scientists have made a significant finding that could lead to better drugs for several degenerative diseases including Huntington's disease and Alzheimer's disease. view more (2008-09-24)
Scientists Develop Method to Track Immune System Enzyme in Live Animals
Scientists supported by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) at the National Institutes of Health have created two mouse strains that will permit researchers to trace, in a live animal, the activity of an enzyme believed to play a crucial role both in the normal immune response as well as autoimmunity... view more... (2007-05-18)
New discovery: if it weren't for this enzyme, decomposing pesticide would take millennia
An enzyme inside a bacterium that grows in the soil of potato fields can - in a split second - break down residues of a common powerful pesticide used for killing worms on potatoes, researchers have found. view more (2005-10-25)
Detailed 3-D image catches a key regulator of neural stem cell differentiation in action
Researchers at the Salk Institute for Biological Studies in collaboration with scientists at the University of California, San Diego (UCSD) took a high resolution "action shot" of a protein switch that plays a crucial role in the development of the nervous system. view more (2006-12-08)
Fox Chase finds that lung cancer patients respond to erlotinib following cetuximab therapy
Non-small cell lung cancer patients who have progressed on a cetuximab-containing regimen may respond to erlotinib, Fox Chase Cancer Center researchers reported today at the annual meeting of the International Association for the Study of Lung Cancer. view more (2009-08-03)
Developing enzymes to clean up pollution by explosives
Scientists at the University of York have uncovered the structure of an unusual enzyme which can be used to reverse the contamination of land by explosives. view more (2009-10-09)
Polycystic kidney disease
The National Institutes of Health (NIH) and the PKD Foundation have launched two treatment trials for autosomal dominant polycystic kidney disease (ADPKD). view more (2006-01-25)
New drug could reduce tissue damage after heart attack
A study led by UCL (University College London) scientists has designed a new drug that inhibits the adverse effects of C reactive protein (CRP), a protein that contributes to tissue damage in heart attacks and strokes. view more (2006-04-27)
Molecular partners required for appropriate neuronal gene repression
In their efforts to understand the complex biology of life, scientists often seek to isolate individual elements of the puzzle for study, to break the problem down to a more manageable size. Single genes and molecules are closely analyzed to better understand their specific interactions with other single entities within larger systems. view more (2005-08-04)
Dual renin system blocking drug combo provides additional blood pressure-lowering effects
A combination of two medicines that act against the effects of the enzyme renin are more effective in lowering blood pressure than either of the medicines alone, according to a study presented today at the American College of Cardiology's 56th Annual Scientific Session. view more (2007-03-27)
HO-1 in sickle cell disease: friend or foe?
Researchers have unexpectedly shown that sickle cell-associated kidney injury may be reduced by inhibiting the enzyme activity of a protein that commonly confers protection in other diseased states. view more (2006-07-20)
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