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Mechanisms that prevent Alzheimer's Disease: Enzymatic activity plays key role
In a project involving the collaboration of several institutes, research scientists of the Johannes Gutenberg University Mainz have succeeded in gaining further insight in the functioning of endogenous mechanisms that protect against the development of Alzheimer's disease. view more (2009-02-24)
Reagent under study as cancer vaccine may also help protect tumors
A bacterial mimic under study as a cancer vaccine because it signals the immune system to attack may also help some tumors hide, researchers have found. view more (2005-11-01)
Penn researchers use honeybee venom toxin to develop a new tool for studying hypertension
Researchers at the University of Pennsylvania School of Medicine have modified a honeybee venom toxin so that it can be used as a tool to study the inner workings of ion channels that control heart rate and the recycling of salt in kidneys. view more (2008-09-18)
New compound unusually potent at blocking brain cancer growth
By determining how a class of compounds blocks signaling in cells, UCSF scientists have identified what is perhaps the most potent drug candidate yet against a highly lethal kind of brain tumor. view more (2006-05-16)
Typhoid carriers: a Salmonella gene mutation?
Salmonella enterica causes approximately 16 million cases of typhoid fever worldwide, killing around 500,000 per year. One in thirty of the survivors, however, become carriers, such as Typhoid Mary who caused several typhoid outbreaks in New York City at the beginning of the last century. In carriers the bacteria remain hidden inside cells and the... view more... (2002-06-25)
Gene test determines risk of heart surgery complications
Genetic differences can explain why some patients undergoing heart surgery later experience shock and kidney complications. view more (2009-05-01)
Novel anticancer strategy moves from laboratory to clinic
Researchers at Emory University have developed a novel anti-tumor compound that represents a distinct strategy: targeting one of the most important "intercept points" for cancer cells. view more (2008-01-04)
Scientists stop colon cancer growth in mice by blocking just one enzyme
In cell culture experiments, scientists from the University of Texas Medical Branch at Galveston (UTMB) and the University of Texas at Arlington determined that stopping the activity of a single enzyme called aldose reductase could shut down the toxic network of biochemical signals that promotes inflammation and colon cancer cell growth. view more (2006-10-02)
Scientists demonstrate feasibility of preventing malaria parasite from becoming sexually mature
Researchers have demonstrated the possibility of preventing the human malaria parasite, Plasmodium falciparum, which is responsible for more than a million malaria deaths a year, from becoming sexually mature. view more (2008-06-03)
Researchers Create Model of Cancer-Preventing Enzyme, Study How It Works
Proline dehydrogenase is important because it plays a role in apoptosis, the process of cell death, by enabling the creation of superoxide, a highly reactive electron-rich oxygen species. view more (2007-05-14)
Tumors use enzyme to recruit regulatory T-cells and suppress immune response
One way tumors fly under the radar of the immune system is by using IDO, an enzyme used by fetuses to help avoid rejection, to recruit powerful regulatory T cells that turn down the immune response, researchers say. view more (2007-08-17)
SUMO protein guides chromatin remodeler to suppress genes
In an in vitro study, led by Grace Gill, PhD, Tufts University School of Medicine, researchers discovered how a protein called SUMO (Small Ubiquitin-related Modifier) guides an enzyme complex that alters the structure of chromatin to regulate expression of genes. view more (2009-04-28)
Naturally fluorescent molecules may serve as cancer biomarker
Excess amounts of a naturally fluorescent molecule found in all living cells could serve as a natural biomarker for cancer, according to bioengineers. view more (2009-04-03)
Simple explanation for complex pattern of feather development
Biologists testing a mathematical model of the mechanism birds use to control the growth of complex feathers found that plumed feather structures involve the coordination of at least two genes that activate and that inhibit barb growth. view more (2005-08-16)
Scientists learn structure of enzyme in unusual virus
Biologists have determined the three-dimensional structure of an unusual viral enzyme that is required in the assembly of new viruses. view more (2007-09-18)
That '4 hour erection': new discovery may help prevent a complication of priapism
For men coping with painful erections lasting for long periods of time, or priapism, new research published online in The FASEB Journal (http://www.fasebj.org) offers hope. view more (2009-10-27)
Gladstone scientists reveal that fat synthesizing enzyme is key to healthy skin and hair
Scientists at the Gladstone Institutes of Cardiovascular Disease (GICD) have found that an enzyme associated with the synthesis of fat in the body is also an element in healthy skin and hair. view more (2009-02-13)
Impersonating nature
Embargoed until 19:00 9 February 2000 view more (2000-02-08)
Nature's weapon against nerve agents
An enzyme found naturally in the blood could help protect soldiers against the effects of the deadly nerve agent sarin, reports Cath O'Driscoll in the Society of Chemical Industry's magazine Chemistry & Industry, the magazine of the SCI. view more (2007-07-30)
Therapeutic effect of imatinib improved with addition of chloroquine
The therapeutic effects of the blockbuster leukemia drug imatinib may be enhanced when given along with a drug that inhibits a cell process called autophagy, researchers from the Kimmel Cancer Center at Jefferson reported in the Journal of Clinical Investigation. view more (2009-04-14)
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