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Proteasome inhibition affects epigenetic mechanisms
Alcohol consumption causes alteration in several cellular mechanisms, and leads to inflammation, apoptosis, immunoresponse defect, and fibrosis. view more (2009-02-19)
Modified plants may yield more biofuel
Plants, genetically modified to ease the breaking down of their woody material, could be the key to a cheaper and greener way of making ethanol, according to researchers who add that the approach could also help turn agricultural waste into food for livestock. view more (2008-12-23)
Broccoli may help protect against respiratory conditions like asthma
Here's another reason to eat your broccoli: UCLA researchers report that a naturally occurring compound found in broccoli and other cruciferous vegetables may help protect against respiratory inflammation that causes conditions like asthma, allergic rhinitis and chronic obstructive pulmonary disease. view more (2009-03-03)
Previously unseen switch regulates breast cancer response to estrogen
A tiny modification called methylation on estrogen receptors prolongs the life of these growth-driving molecules in breast cancer cells, according to research by scientists at Emory University's Winship Cancer Institute. view more (2008-05-09)
Weizmann Institute scientists discover a molecular security mechanism for keeping mutations in check
Everyone knows mutations - genetic mistakes in DNA, the material of heredity - are bad: The more mutations in the cell's DNA, the higher the risk of cancer developing. view more (2006-05-05)
UT Southwestern researchers find gene mutation that leads to 'broken hearts'
Researchers at UT Southwestern Medical Center have identified a group of fruit fly gene mutations responsible for "broken hearts" in the embryonic stages of development, a discovery that could help identify genes that cause human heart defects. view more (2006-07-24)
Green tea boosts production of detox enzymes, rendering cancerous chemicals harmless
Concentrated chemicals derived from green tea dramatically boosted production of a group of key detoxification enzymes in people with low levels of these beneficial proteins, according to researchers at Arizona Cancer Center. view more (2007-08-13)
How Enzymes Work: UB Chemists Publish A Major Discovery
In a publication selected as a "2007 Hot Article" by the journal Biochemistry, University at Buffalo chemists report the discovery of a central mechanism responsible for the action of the powerful biological catalysts known as enzymes. view more (2007-06-20)
Novel fungal enzyme reduces tumour progression
We need oxygen to survive, but ironically oxygen also speeds up aging and can cause cancer! Highly reactive forms of oxygen known as oxygen radicals are produced in our bodies, and this leads to tissue damage and disease. A paper in the June issue of Microbiology reports on a novel enzyme produced by a fungus that can mop up these rogue chemicals... view more... (2001-05-30)
Food With The Guts To Stand Up To Cancer
Cancers of the gut are one of the major causes of death from cancer, but a review published this week[1] shows that they are also amongst the most preventable through changes in diet. Of the 10 million new cases of cancer diagnosed in 2000, around 2.3 million were cancers of the digestive organs - pharynx, oesophagus, stomach or colorectum.... view more... (2004-07-22)
Caught in the act: The dynamic dance of enzymes
In a new study in Nature, Brandeis University Howard Hughes Medical Investigator Dr. Dorothee Kern and collaborators pull back the curtain on the secret lives of enzymes, the ubiquitous proteins that catalyze chemical reactions in the cell. view more (2007-12-12)
Gene-regulating enzyme is also a target for anti-depressive drugs
In 2005, professor Ramin Shiekhattar, Ph.D., at The Wistar Institute and his colleagues reported details about an enzyme involved in appropriately repressing sets of neuronal genes in non-neuronal cells. view more (2006-06-26)
A new way to look at lung cancer and tobacco carcinogens
Two types of cancer-causing agents in cigarettes-a nicotine-derived chemical and polycyclic aromatic hydrocarbons (PAHs) are the main culprits in lung cancer. Exposure to tobacco smoke - both mainstream and second-hand - is a leading cause of cancer death in the United States. view more (2008-05-29)
Genome Sequencing Reveals a Key to Viable Ethanol Production
As the national push for alternative energy sources heats up, researchers at the University of Rochester have for the first time identified how genes responsible for biomass breakdown are turned on in a microorganism that produces valuable ethanol from materials like grass and cornstalks. view more (2007-03-05)
Turning fungus into fuel
A spidery fungus with a voracious appetite for military uniforms and canvas tents could hold the key to improvements in the production of biofuels, a team of government, academic and industry researchers has announced. view more (2008-05-05)
Researchers Develop Simple Method to Create Natural Drug Products
Until now, only the intricate machinery inside cells could take a mix of enzyme ingredients, blend them together and deliver a natural product with an elaborate chemical structure such as penicillin. Researchers at UC San Diego's Scripps Institution of Oceanography and Skaggs School of Pharmacy and Pharmaceutical Sciences and the University of... view more... (2007-09-05)
DNA editing tool flips its target
Imagine having to copy an entire book by hand without missing a comma. Our cells face a similar task every time they divide. They must duplicate both their DNA and a subtle pattern of punctuation-like modifications on the DNA known as methylation. view more (2008-09-04)
Varicella zoster infection causes severe autoimmune hepatitis
Autoimmune hepatitis (AIH) is a chronic liver inflammation of unknown etiology that is characterized by the presence of circulatory autoantibodies and ongoing liver tissue damage. view more (2009-03-03)
Asthma Research Breakthrough Holds Promise Of Cure
New research has made a vital breakthrough in the understanding of how asthma is caused, bringing the possibility of treatments for its prevention and cure. view more (1999-07-06)
Tweaking Taxol points way to a greener, more productive future
As the effective cancer-treatment drug Taxol enters its next generation, Michigan State University announces discoveries which point to both environmentally friendly ways to produce more Taxol, and ultimately innovations to produce a more potent second-generation drug. view more (2006-03-27)
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