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Smoking produces changes in human brain like those in animals using illicit drugs
New research shows for the first time that smoking produces long-lasting biochemical changes in the human brain similar to those changes previously seen in the brains of animals that used cocaine, heroin, and other illicit drugs. view more (2007-02-20)
Workman Lab characterizes novel regulator of chromosome function
The Stowers Institute's Workman Lab has shed new light on a novel histone acetyltransferase protein complex called ATAC. Acetyltransferases are enzymes that introduce a new acetyl functional group into histone proteins, a process by which all chromosome functions are controlled. view more (2008-03-11)
Sweet fuel supply
A new type of fuel cell powered with glucose derived from biomass is described in the latest issue of the Inderscience Publication International Journal of Global Energy Issues. view more (2007-11-28)
Inflammatory processes in arteriosclerosis revealed
Revolutionary new results concerning substances that play major roles in the inflammatory response have been published in the American scientific journal PNAS in two articles from Karolinska Institutet. view more (2006-07-18)
New research to help fight widespread potato disease
Scientists have made a key discovery into the genetics of the bacteria that causes blackleg, an economically damaging disease of potatoes, that could lead to new ways to fight the disease. view more (2007-11-08)
Schepens scientists are first to discover angiogenesis switch inside blood vessel cells
Scientists at Schepens Eye Research Institute, an affiliate of Harvard Medical School, are the first to discover a switch inside blood vessel cells that controls angiogenesis (new blood vessel growth). view more (2006-05-19)
Suspicion lingers over bisphenol A and breast cancer
Bisphenol A, a common industrial chemical claimed to speed the growth of human breast and ovarian cancers, retains its carcinogenic properties even after being modified by body processes. view more (2006-08-28)
UCSD researchers discover cause of rosacea
Doctors can describe the symptoms of rosacea, a common inflammatory skin disease that causes facial redness and affects nearly 14 million Americans. They can tell patients what triggers can worsen their condition: spicy foods, heat, alcohol, even embarrassment. view more (2007-08-06)
Revealing the long-awaited atomic structure of a well-known enzyme
A Boston University-led research team has identified the structural underpinnings of a widely-known enzyme -- acetoacetate decarboxylase (AADase) -- that was first described correctly more than 43 years ago including how it accelerates its target reaction. view more (2009-05-21)
Opening and closing the genome
At any given time, most of the roughly 30,000 genes that constitute the human genome are inactive, or repressed, closed to the cellular machinery that transcribes genes into the proteins of the body. view more (2007-02-26)
EU Funding Helps Improve The Detection of Pesticides in the Environment
The production of more advanced sensors to improve the detection of pesticides in water and other environmental samples has been helped by a grant of almost 1.23 million euro from the EU's Framework Programme. view more (2005-04-29)
Enzyme inhibitor takes an unexpected approach toward blocking cancer-promoting protein
Scientists at Fox Chase Cancer Center have discovered a unique method of attack that may be used to inhibit signaling enzymes called kinases, which often have a role in sustaining drug-resistant cancerous cells. They have confirmed that IPA-3, a small molecular inhibitor of a kinase called PAK1, targets the enzyme's regulatory domain, mimicking... view more... (2009-09-08)
Scripps research scientists develop general-purpose method for detecting trace chemicals
Described in an advance, online publication of the journal Nature Biotechnology on February 22, 2009, the team's general method could be adapted for detecting a wide variety of compounds, including many that are relevant to diagnostic medicine and environmental work. view more (2009-02-26)
Oxford spin-out company may lead to treatments for a range of diseases
Oxford University's latest spin-out company, ReOx, is set to develop potential therapies for a huge range of diseases, from heart disease to stroke, using world-leading expertise in biology and chemistry. The company was spun out this summer and has raised £2 million in capital investment. ReOx is a drug discovery company whose technology... view more... (2003-07-17)
Modelling Life
The Biochemist April 2005 issue: systems biology and mathematical modelling view more (2005-04-01)
Nanoreactors for Reaction Cascades
Living cells are highly complex synthetic machines: Numerous multistep reactions run simultaneously side by side and with unbelievable efficiency and specificity. For these mainly enzymatic reactions to work so well collectively, nature makes use of a variety of concepts. view more (2007-08-21)
Penn researchers determine structure of smallpox virus protein bound to DNA
Researchers at the University of Pennsylvania School of Medicine have determined the structure of an important smallpox virus enzyme and how it binds to DNA. view more (2006-08-07)
Scientists reveal DNA-enzyme interaction with first ever real time footage
For the first time scientists have been able to film, in real-time, the nanoscale interaction of an enzyme and a DNA strand from an attacking virus. view more (2007-09-18)
New study overturns orthodoxy on how macrophages kill bacteria
For decades, microbiologists assumed that macrophages, immune cells that can engulf and poison bacteria and other pathogens, killed microbes by damaging their DNA. A new study from the University of Illinois disproves that. view more (2009-04-28)
Scientists succeed in designing artificial enzymes that also undergo 'evolution in a test tube'
Mankind triumphed in a recent 'competition' against nature when scientists succeeded in creating a new type of enzyme for a reaction for which no naturally occurring enzyme has evolved. This achievement opens the door to the development of a variety of potential applications in medicine and industry. view more (2008-03-25)
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