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MSU 'green chemistry' could ease manufacture, boost usefulness of cancer drug
Research by Michigan State University chemist Kevin Walker is paving the way for potentially cleaner, more efficient production of cancer-fighting paclitaxel - better known as the blockbuster drug Taxol. view more (2009-04-03)
Researchers from CIC bioGUNE have found a way to treat ischemic pathologies
A team of researchers from CIC bioGUNE from the Cellular Biology and Stem Cell Unit, alongside a team from Paris' Cardiovascular Research Centre (INSERM U970) have developed a new area of research which looks extremely promising as regards the development of new therapeutic responses to ischemic pathologies and cardiovascular diseases in general. view more (2009-08-05)
Bacteria could make new library of cancer drugs that are too complex to create artificially
Researchers at the University of Warwick are examining a way of using bacteria to manufacture a new suite of potential anti-cancer drugs that are difficult to create synthetically on a lab bench. view more (2006-11-01)
UC Riverside Researchers Create First Synthetic Cellulosome in Yeast
A team of researchers led by University of California, Riverside (UCR) Professor of Chemical Engineering Wilfred Chen has constructed for the first time a synthetic cellulosome in yeast, which is much more ethanol-tolerant than the bacteria in which these structures are normally found. view more (2009-10-30)
In India: A search for more effective tuberculosis drugs
Rajesh Gokhale has created a compound in his lab in India that stops tuberculosis in its tracks. In a test tube, the molecule hits four of the bacterium's crucial metabolic pathways at the same time, weakening and ultimately destroying the pathogen. view more (2009-02-02)
Molecular probe 'paints' cancer cells in living animals, Stanford researchers find
Researchers at the Stanford University School of Medicine have developed a molecular probe that sets aglow tumor cells within living animals. Their goal is to use the probe to improve the diagnosis and treatment of cancer and other diseases. view more (2007-09-10)
UI chemists' DNA biosynthesis discovery could lead to better antibiotics
Combating several human pathogens, including some biological warfare agents, may one day become a bit easier thanks to research reported by a University of Iowa chemist and his colleagues in the April 16 issue of the journal Nature. view more (2009-04-17)
Catalyst mystery unlocked
Different keys are not supposed to fit the same lock, but in biological systems multiple versions of a catalyst all make a reaction go, according to a new study that explains the phenomenon. view more (2008-08-19)
Fatty Liver a Possible Risk for Hypertension
The accumulation of fat in the liver, or "fatty liver," resulting from accumulation of central body fat, and perhaps not alcohol consumption, may represent an important underlying mechanism for the association between liver enzymes and hypertension. view more (2005-11-03)
Scripps research team unravels new cellular repair mechanism
The cell cycle, which allows cells to replicate their DNA and produce new cells, is controlled by a complex concert of enzymes and other components. In addition there are "checkpoint" mechanisms that can block continuation of the process if something goes amiss. view more (2008-08-07)
New marker for Alzheimer's discovered
Gothenburg researchers have discovered a previously unknown substance in spinal fluid that can be used to diagnose Alzheimer's disease. view more (2009-09-15)
Enzyme Structure Reveals New Drug Targets for Cancer and Other Diseases
If the genome is the parts list of the human cell, certain proteins are the production managers, activating and deactivating genes as needed. Scientists funded by the National Institute of General Medical Sciences (NIGMS), part of the National Institutes of Health, now have a clearer understanding of how a key protein controls gene activity and... view more... (2008-02-15)
Durability of dental fillings improves if the enzyme activity of teeth is inhibited
Composite dental fillings have one problematic feature, in that the bond between the filling and the dental tissue deteriorates over time - in fact, sometimes by as much as 50 per cent in one year. As the bond deteriorates, it may allow bacteria to enter and this brings a high risk of further tooth decay. view more (2009-02-12)
Skin cancer study uncovers new tumor suppressor gene
National Institutes of Health (NIH) researchers have identified a gene that suppresses tumor growth in melanoma, the deadliest form of skin cancer. view more (2009-03-30)
Scripps scientists develop first examples of RNA that replicates itself indefinitely
Findings could inform biochemical questions about how life began. Now, a pair of Scripps Research Institute scientists has taken a significant step toward answering that question. The scientists have synthesized for the first time RNA enzymes that can replicate themselves without the help of any proteins or other cellular components, and the... view more... (2009-01-12)
Boron-based compounds trick a biomedical protein
Chemists and biologists have successfully demonstrated that specially synthesized boron compounds are readily accepted in biologically active enzymes, a move that, they say, is a proof of concept that could lead to new drug design strategies. view more (2009-09-03)
Plant pathogen yields substance to fight neuroblastoma
Drug treatment of neuroblastoma, a tumor of the nervous system in children, poses major problems. Therefore, scientists at the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) have been searching for substances that are suitable as a basis for developing better drugs. Now they have found a candidate: HC-toxin, which is... view more... (2008-01-18)
African parasite makes component of fat differently from all other organisms
Studying the parasite that causes African sleeping sickness, scientists at Johns Hopkins have discovered a previously unknown way of making fatty acids, a component of fat and the outer layer of all cells. view more (2006-08-25)
UC Davis researchers discover genetic switch involved in cells' response to radiation therapy
UC Davis Cancer Center researchers have discovered a genetic switch that causes cancer cells to become more sensitive to a drug administered to enhance radiation therapy effectiveness. view more (2005-11-17)
Acne medication associated with abnormal blood test results
Elevated cholesterol levels and liver enzyme levels appear to be more common than previously thought among patients taking the acne medication isoretinoin, including those who had normal blood test results before beginning therapy. view more (2006-08-22)
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