Epigenetic Silencing Current Events | Epigenetic Silencing News | 2
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Scientists find clue to mechanisms of gene signaling and regulation
Scientists have discovered a pattern in the DNA sequence of the mouse genome that may play a fundamental part in the way DNA molecules regulate gene expression. view more (2007-08-23)
Bread mold may hold secret to eliminating disease-causing genes
When most people discover mold on their bread, they immediately throw it out. Others see a world of possibilities in the tiny fungus. A University of Missouri scientist, along with a collaborative research team, has examined a new mechanism in the reproductive cycle of a certain species of mold. view more (2008-05-09)
Proteasome inhibition affects epigenetic mechanisms
Alcohol consumption causes alteration in several cellular mechanisms, and leads to inflammation, apoptosis, immunoresponse defect, and fibrosis. view more (2009-02-19)
Rethinking the genetic theory of inheritance
Scientists at the Centre for Addiction and Mental Health (CAMH) have detected evidence that DNA may not be the only carrier of heritable information; a secondary molecular mechanism called epigenetics may also account for some inherited traits and diseases. view more (2009-01-20)
Scientists Take Early Steps Toward Mapping Epigenetic Variability
The study of eipigenetic variability in cells and tissues could someday help diagnose diseases more precisely and provide more targeted treatments for chronic ailments. view more (2009-08-17)
New view of cancer: 'Epigenetic' changes come before mutations
A Johns Hopkins researcher, with colleagues in Sweden and at the Fred Hutchinson Cancer Research Center, suggests that the traditional view of cancer as a group of diseases with markedly different biological properties arising from a series of alterations within a cell's nuclear DNA may have to give way to a more complicated view. view more (2005-12-22)
Changes to DNA linked to diabetes
Genes that regulate the energy consumption of cells have a different structure and expression in type II diabetics than they do in healthy people, according to a new study from the Swedish medical university Karolinska Institutet published in Cell Metabolism. view more (2009-09-02)
CSHL researchers map changing epigenetic modifications that enable transposons to run amok
Much like cancer cells, plant cells grown for a long time outside of their normal milieu, in culture dishes, have highly unstable genomes. view more (2008-12-11)
Computation to unravel how genes are regulated and shed light on how cells become different
A closer alliance between computational and experimental researchers is needed to make progress towards one of biology's most challenging goals, understanding how epigenetic marks contribute to regulation of gene expression. view more (2008-04-11)
Novel epigenetic markers of melanoma may herald new treatments for patients
Melanoma is the most serious form of skin cancer, diagnosed in more than 50,000 new patients in the United States annually. While the rate of incidences continues to rise, survival rate has not improved and the race is on to find the genetic and cellular changes driving melanoma and to devise new means of detection and treatment. view more (2009-06-30)
Newly-discovered mechanism can explain the Beckwith-Wiedemann syndrome
Researchers from Uppsala University have discovered a mechanism that silences several genes in a chromosome domain. The findings, published in today's on-line issue of Molecular Cell, have implications in understanding the human disorder Beckwith-Wiedemann syndrome. view more (2008-10-27)
A new gene silencing platform -- silence is golden
A team of researchers led by Rutgers' Samuel Gunderson has developed a novel gene silencing platform with very significant improvements over existing RNAi approaches. view more (2009-02-09)
Food additive inhibits longevity enzyme in yeast, increases cell toxicity, new study finds
A common additive found in food and cosmetics has been found to inhibit the activity of sirtuins, enzymes associated with lifespan control in yeast and other organisms, according to a new study led by researchers at the University of California, Berkeley. view more (2005-12-16)
Evolutionarily preserved mechanism governs use of genes
Researchers at Uppsala University have found that the protein coding parts of a gene are packed in special nucleosomes. The same type of packaging is found in the roundworm C elegans, which is a primeval relative of humans. view more (2009-08-18)
100 reasons to change the way we think about genetics
For years, genes have been considered the one and only way biological traits could be passed down through generations of organisms. view more (2009-05-19)
Researchers solve piece of large-scale gene silencing mystery
A team led by Craig Pikaard, Ph.D., Washington University in St. Louis professor of biology in Arts & Sciences, has made a breakthrough in understanding the phenomenon of nucleolar dominance, the silencing of an entire parental set of ribosomal RNA genes in a hybrid plant or animal. view more (2008-12-05)
First evidence that prenatal exposure to famine may lead to persistent epigenetic changes
A study initiated by researchers at Columbia University Mailman School of Public Health and the Leiden University Medical Center in the Netherlands suggests that prenatal exposure to famine can lead to epigenetic changes that may affect a person's health into midlife. view more (2008-10-31)
Our genome changes over lifetime, Johns Hopkins experts say
Researchers at Johns Hopkins have found that epigenetic marks on DNA-chemical marks other than the DNA sequence-do indeed change over a person's lifetime, and that the degree of change is similar among family members. view more (2008-06-25)
Study links breast cancer risk to epigenetic changes related to race, smoking and birth size
Women can encounter environmental factors that increase their risk of breast cancer at various periods of their physical development, beginning before birth and extending until menopause. view more (2007-04-16)
Specific genetic cause of fetal alcohol-related developmental disorders found
Alcohol consumption by pregnant women hinders brain development in their children by interfering with the genetic processes that control thyroid hormone levels in the fetal brain, a new animal study found. view more (2009-06-11)
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