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RNA interference therapy heals growth deficiency disorder in a live animal
A team of Vanderbilt researchers have demonstrated for the first time that a new type of gene therapy, called RNA interference, can heal a genetic disorder in a live animal. view more (2007-12-19)
Making memories that last a lifetime
Neurobiologists have discovered a mechanism by which the constantly changing brain retains memories—from that dog bite to that first kiss. They have found that the brain co-opts the same machinery by which cells stably alter their genes to specialize during embryonic development. view more (2007-03-15)
Effects of aging in stem cells
There is little disagreement that the body's maintenance and repair systems deteriorate with age, even as there is plenty of disagreement as to why. view more (2007-07-24)
Twin molecular scissors link creation of microRNAs with gene-silencing
One of the body's primary strategies for regulating its genome is a kind of targeted gene silencing orchestrated by small molecules called microRNAs, or miRNAs. view more (2005-11-04)
New Genetic Mechanism For Evolution
A team of researchers from the Universitat Autònoma de Barcelona (UAB) has discovered that transposons, small DNA sequences that travel through the genomes, can silence the genes adjacent to them by inducing a molecule called antisense RNA. This is a new mechanism for evolution that has been unknown until now. The research has been recently... view more... (2004-07-16)
The new 'epigenetics:' Poor nutrition in the womb causes permanent genetic changes in the offspring
The new science of epigenetics explains how genes can be modified by the environment, and a prime result of epigenetic inquiry has just been published online in The FASEB Journal: You are what your mother did not eat during pregnancy. view more (2009-04-14)
CellCentric and the Babraham Institute announce cooperation
CellCentric and the Babraham Institute in Cambridge, one of Europe's leading centres of excellence in epigenetic research, will work together in the exploitation of epigenetics. view more (2005-04-07)
Progress made in understanding causes and treatment of endometriosis
Endometriosis is a poorly understood chronic disease characterized by infertility and chronic pelvic pain during intercourse. It affects between 5 to 10 million women in the U.S. view more (2009-01-20)
Mapping dynamic Polycomb group proteins during Drosophila development
The developmental passage from a ball of cells to a fruit-fly is a very complicated process involving both temporal and spatial regulation of genes and pathways. view more (2006-04-20)
Small RNAs can play critical roles in male infertility/contraception
University of Nevada School of Medicine scientists in the Department of Physiology and Cell Biology have discovered insight into the reproductive workings of the male sex chromosome that may have significant implications for male infertility and contraception. view more (2009-04-10)
Vitamin extends life in yeast, Dartmouth Medical School researchers find
Imagine taking a vitamin for longevity! Not yet, but a Dartmouth discovery that a cousin of niacin prolongs lifespan in yeast brings the tantalizing possibility a step closer. view more (2007-05-04)
Cancer is a stem cell issue
There is an urgent reason to study stem cells: stem cells are at the heart of some, if not all, cancers. view more (2007-02-20)
Mice cloned from skin cells
Healthy and viable mice that survive until adulthood have, for the first time, been cloned from adult stem cells. Scientists from Rockefeller University, including Howard Hughes Medical Institute investigator Elaine Fuchs, used cells called keratinocyte stem cells, which represent a new model system for cloning. view more (2007-02-13)
Stowers Institute's Workman Lab discovers novel histone demethylase protein complex
The Stowers Institute's Workman Lab has discovered a novel histone demethylase protein complex characterized in work published today in Molecular Cell. view more (2008-12-08)
Getting down to cancer basics
Researchers have identified a new cancer gene - one that is common to many cancers and affects the most basic regulation of our genes. The new example - a gene on the X chromosome called UTX - is found in 10% of cases of multiple myeloma and 8% of esophageal cancers. view more (2009-03-30)
Class of antibiotics can enhance gene-silencing tool
A way to turn off one gene at a time has earned acceptance in biology laboratories over the last decade. Doctors envision the technique, called RNA interference, as a tool to treat a variety of diseases if it can be adapted to humans. view more (2008-07-21)
UK physician revolutionizes gene research
A dramatic new study published in the most recent issue of Nature questions some of the mechanisms underlying a new class of drugs based on Nobel Prize-winning work designed to fight diseases ranging from macular degeneration to diabetes. view more (2008-03-27)
Resetting epigenetic code could aid lupus patients
Researchers at Wake Forest University School of Medicine and the University of Virginia hope to reset part of the "epigenetic code" in lupus patients and thus improve treatment. view more (2005-11-08)
RNA molecules, delivery system improve vaccine responses, effectiveness
A novel delivery system that could lead to more efficient and more disease-specific vaccines against infectious diseases has been developed by biomedical engineers at The University of Texas at Austin. view more (2008-10-09)
Brain DNA 'remodeled' in alcoholism
Reshaping of the DNA scaffolding that supports and controls the expression of genes in the brain may play a major role in the alcohol withdrawal symptoms, particularly anxiety, that make it so difficult for alcoholics to stop using alcohol. view more (2008-04-02)
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