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Targeting a key enzyme with gene therapy reversed course of Alzheimer's disease in mouse models
In mice, that had been genetically engineered to develop Alzheimer's disease, scientists were able to reverse the rodents' memory loss by reducing the amount of an enzyme that is crucial for the development of Alzheimer's disease. view more (2005-09-22)
Evolution of genomic imprinting
How we come to express the genes of one parent over the other is now better understood through studying the platypus and marsupial wallaby - and it doesn't seem to have originated in association with sex chromosomes. view more (2007-09-07)
DNA methylation shown to promote development of colon tumors
Damaged or defective genes have long been known to be the cause of some cancers. Over the past decade, however, scientists have discovered that even healthy genes can be switched on or off and can cause cancer without any changes in the underlying DNA sequence-although how this happens has remained poorly understood. view more (2007-12-03)
New behavior may use old genes
Though you may not be able to teach an old dog new tricks, ASU researchers have found that evolution may have taught old genes new tricks in the development of social behavior in honeybees. view more (2006-10-26)
Tool developed to silence genes in specific tissues using RNAi
Researchers at The University of Texas M. D. Anderson Cancer Center say they have jumped a significant hurdle in the use of RNA interference (RNAi), believed by many to be the ultimate tool to both decode the function of individual genes in the human genome and to treat disease. view more (2006-01-17)
DNA test shows promise for identifying patients with colorectal cancer (p 1283)
Testing for DNA changes in stools might provide a new, accurate, and less invasive way to screen patients for colorectal cancer, conclude the authors of a research letter in this week's issue of THE LANCET. Colorectal cancer is one of the most common cancers in the industrialised world, and early detection might help to reduce the risk of death... view more... (2004-04-14)
Perinatal environment influences aggression in children
It's a well-documented fact that children from zero to two can be spontaneously aggressive and that boys can be among the worse culprits. Even after being socialized, seven percent of boys will continue to be hyper-aggressive until the age of nine. view more (2009-03-11)
A breakthrough in gastric carcinogenesis
Checkpoint with forkhead and ring finger (CHFR) is a mitotic stress checkpoint gene whose promoter is frequently methylated in various kinds of cancer. view more (2009-06-12)
Scientists discover stage at which an embryonic cell is fated to become a stem cell
Cambridge scientists have discovered the stage at which some of the cells of a fertilised mammalian egg are fated to develop into stem cells and why this occurs. view more (2007-01-11)
ossible drug target for obesity treatment a no-brainer: UNC study
Scientists at the University of North Carolina at Chapel Hill School of Medicine have discovered a gene that when mutated causes obesity by dampening the body's ability to burn energy while leaving appetite unaffected. view more (2009-02-05)
UCSB researchers develop drug delivery system using nanoparticles and lasers
Researchers at UC Santa Barbara have developed a new way to deliver drugs into cancer cells by exposing them briefly to a non-harmful laser. view more (2009-09-10)
Genes involved in cell growth and cell division identified
A recent study shows that hundreds of genes contribute to cell growth and cell division. For the first time these genes, many of which are potential contributors to cancer, have been mapped in a single systematic study. view more (2006-02-23)
Interfering RNA silences genes in 'slippery' immune cells
A technical advance in laboratory techniques may provide biology researchers broader access to RNA interference, a process of blocking the activity of targeted genes. view more (2006-05-09)
PPAR-g agonists have potential therapeutic role in gastric carcinoma?
Recently, the potential of PPAR-γ as a target for the prevention and treatment of cancer has been widely studied. view more (2009-08-27)
'Insulator' helps silence genes in dormant herpes virus
By adulthood, most people have suffered at least one bout of painful cold sores brought on by the Herpes simplex virus 1, also known as HSV-1. view more (2007-05-03)
Researchers reveal repressor protein blocks neural stem cell development
A protein known to repress gene transcription at the molecular level in a variety of processes also blocks embryonic neural stem cells from differentiating into neurons. view more (2007-10-11)
A potential therapeutic target for gastric cancer
Gastric cancer (GC) is the fourth most common malignancy and the second most frequent cause of cancer-related death in the world. view more (2009-04-17)
Gene therapy 'turns off' mutation linked to Parkinson's disease
A group of Northwestern University researchers is developing a novel gene therapy aimed at selectively turning off one of the genes involved in the development of Parkinson's disease. view more (2006-01-19)
New therapeutic strategy could target toxic protein in most patients with Huntington's disease
Howard Hughes Medical Institute researchers have designed tiny RNA molecules that shut off the gene that causes Huntington's disease without damaging that gene's healthy counterpart, which maintains the health and vitality of neurons. view more (2009-04-10)
Gene packaging tells story of cancer development
To decipher how cancer develops, Johns Hopkins Kimmel Cancer Center investigators say researchers must take a closer look at the packaging. view more (2008-12-05)
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