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Epigenetic Silencing Current Events | Epigenetic Silencing News | 8

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Knockout broccoli fights cancer
EATING your greens could be even better for you than anyone thought. Macerated raw broccoli turns out to contain small amounts of a potent chemical that inhibits the oxidising enzymes that damage DNA and potentially cause cancer. When you chew broccoli, its cells rupture, releasing an enzyme that produces a class of chemicals called... view more... (2003-04-05)

Adult offspring of parents with PTSD have lower cortisol levels
A small study suggests that adults whose parents are Holocaust survivors with post-traumatic stress disorder (PTSD) appear to have lower average levels of the stress hormone cortisol than the adult offspring of parents without PTSD.   view more (2007-09-04)

Montreal researchers probe the genetic basis of memory
A group of Montreal researchers has discovered that GCN2, a protein in cells that inhibits the conversion of new information into long-term memory, may be a master regulator of the switch from short-term to long-term memory.   view more (2005-08-31)

Gerton Lab determines the composition of centromeric chromatin
The Stowers Institute's Gerton Lab has provided new evidence to clarify the structure of nucleosomes containing Cse4, a centromere-specific histone protein required for proper kinetochore function, which plays a critical role in the process of mitosis. The work, conducted in yeast cells, was published in the most recent issue of Molecular Cell.    view more (2009-09-29)

Men with multiple sclerosis pass disease to offspring more often than women
According to a new study, men transmit multiple sclerosis (MS) to their children 2.2 times more often than women in families where the father or mother and a child have multiple sclerosis.   view more (2006-07-25)

Memory machine
What happens in our brains when we learn and remember" Are memories recorded in a stable physical change, like writing an inscription permanently on a clay tablet" Prof. Yadin Dudai, Head of the Weizmann Institute's Neurobiology Department, and his colleagues are challenging that view.   view more (2007-08-17)

Estrogen protects liver after traumatic injury
Researchers have identified the receptor pathway used by estrogen to decrease liver injury after trauma and hemorrhage.   view more (2007-04-02)

Prenatal Genistein In Soy Reduces Obesity In Offspring
A single nutrient found in soy products elicits changes in gene behavior that permanently reduce an embryo's risk of becoming obese later in life, according to an animal study at Duke University Medical Center.   view more (2006-03-29)

Tolerance to inhalants may be caused by changes in gene expression
Changes in the expression of genes may be the reason why people who abuse inhalants, such as spray paint or glue, quickly develop a tolerance, biologists at The University of Texas at Austin have discovered.   view more (2007-10-18)

Helping Tomatoes Cope With Stress May Be Good For Us
Scientists at the John Innes Centre (JIC)(1) and Institute of Food Research (IFR)(2), Norwich, have today reported the discovery and use of a gene that may help protect plants and humans against disease. The gene (HQT) was identified in tomato and is responsible for producing an antioxidant called chlorogenic acid (CGA). By increasing the... view more... (2004-04-26)

Faulty DNA repair could be a risk factor for lung cancer in nonsmokers
People who have never smoked but whose cells cannot efficiently repair environmental insults to DNA are at higher risk of developing lung cancer than those with effective genomic repair capability.   view more (2008-06-26)

A genetic 'gang of 4' drives spread of breast cancer
Studies of human tumor cells implanted in mice have shown that the abnormal activation of four genes drives the spread of breast cancer to the lungs.   view more (2007-04-12)

New route for heredity bypasses DNA
A group of scientists in Princeton's Department of Ecology and Evolutionary Biology has uncovered a new biological mechanism that could provide a clearer window into a cell's inner workings.   view more (2008-01-07)

Successful cell engineering may lead to mad cow prevention, say researchers
Researchers at Texas A&M University have successfully "knocked down" the expression of possible disease-causing genes in a cloned goat fetus, perhaps paving the way for breeding disease resistance in other animals, even those genes that might cause bovine spongiform encephalopathy (BSE), commonly known as Mad Cow Disease.   view more (2006-03-23)

A miR boost enables acute leukemia cells to mature
A new study by Ohio State University cancer researchers shows that boosting the level of a molecule called miR-29b in acute myeloid leukemia (AML) cells can reverse gene changes that trap the cells in an immature, fast growing state of development.   view more (2009-04-03)

Weeding out marijuana: Researchers close in on engineering recognizable, drug-free Cannabis plant
In a first step toward engineering a drug-free Cannabis plant for hemp fiber and oil, University of Minnesota researchers have identified genes producing tetrahydrocannabinol (THC), the psychoactive substance in marijuana. Studying the genes could also lead to new and better drugs for pain, nausea and other conditions.   view more (2009-09-16)

Researchers at Vanderbilt-Ingram Cancer Center uncover clue to explain invasive brain tumors
Researchers at the Vanderbilt-Ingram Cancer Center have uncovered a clue to explain the invasive nature of an aggressive kind of brain tumor called glioblastoma multiforme, or gliomas.   view more (2006-01-12)

Model identifies genes that induce normal skin cells to become abnormal
Northwestern University researchers have developed a novel, three-dimensional model that allows scientists to observe how interacting with the microenvironment of metastatic melanoma cells induces normal skin cells to become similar to aggressive cancer cells that migrate and spread throughout the body.   view more (2005-11-15)

Penn researchers discover 'modus operandi' of heart muscle protein
Researchers at the University of Pennsylvania School of Medicine have discovered that a protein called leiomodin (Lmod) promotes the assembly of an important heart muscle protein called actin. What's more, Lmod directs the assembly of actin to form the pumping unit of the heart. The findings appear in this week's issue of Science.   view more (2008-04-11)
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