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Epigenetic changes discovered in major psychosis
Scientists have discovered epigenetic changes (i.e. chemical changes to a gene that do not alter the DNA sequence) in individuals with schizophrenia and bipolar disorder. This is the first epigenome-wide investigation in psychiatric research, and this groundbreaking data may be a significant step... view more (2008-03-12)

Cancer scientists call for a large-scale human epigenome project
A vast code, invisible to the DNA sequencing effort that constituted the Human Genome Project, is rapidly being shown to play a direct role in human health. This "epigenome"-from the Greek epi, meaning "in addition to"-consists of chemical "amendments" that dangle like... view more (2005-12-15)

Epigenetic research uncovers new targets for modification enzymes
Enzymes regulating genetic expression can be just as important as the genome itself, increasing evidence shows. The expanding field of epigenetics focuses on the multiple influences on DNA and surrounding molecules that determine whether genes are turned on or off during development and disease... view more (2008-04-28)

Circadian rhythm-metabolism link discovered
UC Irvine researchers have found a molecular link between circadian rhythms - our own body clock - and metabolism. The discovery reveals new possibilities for the treatment of diabetes, obesity and other related diseases.   view more (2008-07-25)

A Molecular Basis for Cocaine Abuse: PLoS Biology Press Release
This Is Your Fly's Brain on Drugs Cocaine addiction wreaks profound changes on the brain, hijacking reward circuits and depressing inhibitory loops to the point that drug seeking and taking become central drivers of behavior. While mammalian models are useful for mapping out the neural complexity... view more (2004-11-16)

UD leads $5.3-million research project on rice epigenetics
Using a novel "deep sequencing" technology that can in one fell swoop decode 50 million sequences representing well over a billion bases of DNA, a research team led by University of Delaware scientists is working to unmask where, why and how certain genes are switched on or off in rice--a... view more (2007-09-11)

Prenatal Genistein In Soy Reduces Obesity In Offspring
A single nutrient found in soy products elicits changes in gene behavior that permanently reduce an embryo's risk of becoming obese later in life, according to an animal study at Duke University Medical Center.   view more (2006-03-29)

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