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Epigenetic changes discovered in major psychosis
Scientists have discovered epigenetic changes (i.e. chemical changes to a gene that do not alter the DNA sequence) in individuals with schizophrenia and bipolar disorder. This is the first epigenome-wide investigation in psychiatric research, and this groundbreaking data may be a significant step on the journey to fully understanding major... view more... (2008-03-12)

Cancer scientists call for a large-scale human epigenome project
A vast code, invisible to the DNA sequencing effort that constituted the Human Genome Project, is rapidly being shown to play a direct role in human health. This "epigenome"-from the Greek epi, meaning "in addition to"-consists of chemical "amendments" that dangle like charms on a bracelet from the linear string of... view more... (2005-12-15)

Therapeutic cloning gets a boost with new research findings
Germ cells, the cells which give rise to a mammal's sperm or eggs, exhibit a five to ten-fold lower rate of spontaneous point mutations than adult somatic cells, which give rise to the body's remaining cell types, tissues and organs. Despite their comparatively higher mutation rates, however, adult somatic cells are used as the donor cells in a... view more... (2009-03-25)

Scientists Take Early Steps Toward Mapping Epigenetic Variability
The study of eipigenetic variability in cells and tissues could someday help diagnose diseases more precisely and provide more targeted treatments for chronic ailments.   view more (2009-08-17)

Scientists map epigenome of human stem cells during development
Scientists at The Genome Institute of Singapore (GIS) and The Scripps Research Institute (TSRI) led an international effort to build a map that shows in detail how the human genome is modified during embryonic development.    view more (2010-02-04)

Epigenetic research uncovers new targets for modification enzymes
Enzymes regulating genetic expression can be just as important as the genome itself, increasing evidence shows. The expanding field of epigenetics focuses on the multiple influences on DNA and surrounding molecules that determine whether genes are turned on or off during development and disease processes.   view more (2008-04-28)

Epigenetics could help researchers determine any risks associated with low-dose radiation
There remains a lack of consensus amongst the medical and scientific communities about any cancer risk from low level radiation, particularly low-dose radiation delivered from computed tomography (CT) scans.   view more (2010-02-01)

New nucleotide could revolutionize epigenetics
Anyone who studied a little genetics in high school has heard of adenine, thymine, guanine and cytosine -- the A,T,G and C that make up the DNA code.   view more (2009-04-17)

Researchers find epigenetic signals differ across alleles
Researchers from the Institute of Psychiatry (IoP), King's College London, have identified numerous novel regions of the genome where the chemical modifications involved in controlling gene expression are influenced by either genetic variation or the parental origin of that particular stretch of DNA.   view more (2010-02-16)

Scripps Research and GIS scientists map epigenome of human stem cells during development
Scientists at The Scripps Research Institute and The Genome Institute of Singapore (GIS) led an international effort to build a map that shows in detail how the human genome is modified during embryonic development.    view more (2010-02-04)

Circadian rhythm-metabolism link discovered
UC Irvine researchers have found a molecular link between circadian rhythms - our own body clock - and metabolism. The discovery reveals new possibilities for the treatment of diabetes, obesity and other related diseases.   view more (2008-07-25)

A Molecular Basis for Cocaine Abuse: PLoS Biology Press Release
This Is Your Fly's Brain on Drugs Cocaine addiction wreaks profound changes on the brain, hijacking reward circuits and depressing inhibitory loops to the point that drug seeking and taking become central drivers of behavior. While mammalian models are useful for mapping out the neural complexity of these behaviors, insights into the molecular... view more... (2004-11-16)

Einstein scientists propose new theory of autism
Scientists at Albert Einstein College of Medicine of Yeshiva University have proposed a sweeping new theory of autism that suggests that the brains of people with autism are structurally normal but dysregulated, meaning symptoms of the disorder might be reversible.   view more (2009-04-02)

New Method Developed by UC San Diego Bioengineers Gives Regenerative Medicine a Boost
Bioengineers at UC San Diego have developed a breakthrough method for sequencing-based methylation profiling, which could help fuel personalized regenerative medicine and even lead to more efficient and cost-effective methods for studying certain diseases.   view more (2009-04-24)
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