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Epithelial Cells Current Events | Epithelial Cells News | 8

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DFG remains skeptical of the cloning of human cells
According to a paper published in the journal Stem Cells, an American group has succeeded in inserting cell nuclei from human skin cells into human enucleated oocytes and to stimulate these new cells to undergo cell division in the laboratory.   view more (2008-01-23)

A link between mitochondria and tumor formation in stem cells
Researchers report on a previously unknown relationship between stem cell potency and the metabolic rate of their mitochondria -a cell's energy makers. Stem cells with more active mitochondria also have a greater capacity to differentiate and are more likely to form tumors.   view more (2008-10-13)

U-M scientists target key cells and signals that trigger pulmonary fibrosis
Scientists at the University of Michigan Medical School have identified biochemical signals that attract pathogenic cells to damaged lung tissue - one of the first steps in a chain of events leading to a lethal disease called idiopathic pulmonary fibrosis or IPF.   view more (2006-05-24)

New study shows that important gene controls the ability of the thymus to produce disease-fighting T-cells after an organism's birth
New research, just published by researchers from the University of Georgia, provides the first evidence that a key gene may be crucial to maintaining the production of the thymus and its disease-fighting T-cells after an animal's birth.   view more (2008-11-07)

Cell removal technique could lead to cheaper drugs
Researchers at the University of Edinburgh have pioneered a simple way to remove dead cells from cell cultures used to make protein-based drugs, which are increasingly prescribed to treat a range of illnesses.   view more (2008-08-27)

Deakin University research finds rogue cells that could cause spread of breast cancer
Stephanie Lebret completed the study for her PhD at Deakin's Centre for Cellular and Molecular Biology under the supervision of Associate Professor Leigh Ackland.   view more (2007-06-14)

Donor T cells change the fate of stem cells in transplantation
When a transplant patient suffers complications such as graft rejection or graft-versus-host disease, physicians attempt to stop the body's immune response by targeting a patient's T cells.   view more (2006-07-13)

Cellular antacids give vaccines a boost
Scientists in Italy have found that a drug that blocks acid buildup inside cells revs up the immune response to vaccines.   view more (2005-09-12)

Drawing a crowd: How progenitor cells are recruited to tumor blood vessels from the bone marrow
Cells within the bone marrow (progenitor cells) that express a protein called CD34 have been shown to leave the marrow and travel to sites of tissue injury to mediate repair.   view more (2006-02-24)

Combination therapy with a monocloncal antibody and a vaccine leads to tumor rejection
Effector T cells (Teff cells) are involved in activating and directing other immune cells, while regulatory T cells (Tregs) act to curb the over-aggressive responses of the T cell population.   view more (2006-06-16)

A step forward in stem cell research
According to research published today, investigators from Memorial Sloan-Kettering Cancer Center (MSKCC) have used new techniques in the laboratory that allowed them for the first time to derive unlimited numbers of purified mesenchymal precursor cells from human embryonic stem cells (HESCs).   view more (2005-06-27)

U of MN researchers use human embryonic stem cells to kill cancer cells
For the first time, stem cell researchers at the University of Minnesota have coaxed human embryonic stem cells to create cancer-killing cells in the laboratory, paving the way for future treatments for various types of cancers (or tumors).   view more (2005-10-12)

Synthetic virus supports a bat origin for SARS
SARS - severe acute respiratory syndrome - alarmed the world five years ago as the first global pandemic of the 21st century. The coronavirus (SARS-CoV) that sickened more than 8,000 people - and killed nearly 800 of them - may have originated in bats, but the actual animal source is not known.   view more (2008-11-26)

When is a stem cell not really a stem cell?
Working with embryonic mouse brains, a team of Johns Hopkins scientists seems to have discovered an almost-too-easy way to distinguish between "true" neural stem cells and similar, but less potent versions.   view more (2007-08-27)

Early signs that adult bone-marrow stem cells could regenerate brain tissue (p 1432)
Findings of a preliminary study in this week's issue of THE LANCET suggest that transplanted adult bone-marrow cells could regenerate nerve cells in the brains of human stem-cell recipients. These early findings, if confirmed in future research, have implications for the treatment of... view more (2004-04-28)

Jefferson researchers find nanoparticle shows promise in reducing radiation side effects
Using transparent zebrafish embryos, researchers at Jefferson Medical College have shown that a microscopic nanoparticle can help fend off damage to normal tissue from radiation.   view more (2005-11-15)

Modified bone marrow cells can help recovery in an animal model of multiple sclerosis
A new study published in PLoS Medicine has shown that modified bone marrow cells can help recovery in an animal model of multiple sclerosis (MS).   view more (2007-04-10)

Scientists make first step towards growing human lungs for transplant
Scientists have successfully converted human embryonic stem cells into lung cells, taking a first step towards building human lungs for transplantation.   view more (2005-08-23)

Treating male infertility with stem cells
New research has examined the usefulness of bone marrow stem cells for treating male infertility, with promising results. The related report by Lue et al, "Fate of bone marrow stem cells transplanted into the testis: potential implication for men with testicular failure," appears in the... view more (2007-03-02)

Cancer cells lose drug resistance following electrical stimulation in vitro
Drug-resistant tumour cells lose their drug resistance when exposed to low intensity, low frequency electric pulses for three days.   view more (2006-03-17)

Stem cell identity in culture may strongly depend on the cellular microenvironment
Identification, isolation and large scale culture of stem cells for potential medical applications is a major challenge in cell biology.   view more (2007-04-25)

Signaling for cartilage
Skeletal progenitor cells differentiate into cartilage cells when one master gene actually suppresses the action of another, said Baylor College of Medicine researchers in a report that appears online in the journal Proceedings of the National Academy of Sciences.   view more (2006-11-28)

Link between chronic kidney disease and oxygen-deprived tissue
Researchers at the University of Pennsylvania School of Medicine have discovered how low-oxygen conditions can worsen chronic kidney disease (CKD).   view more (2007-12-19)

Dampened hopes for transplanting bone marrow stem cells in heart attacks
There is little, if any, evidence that adult stem cells can build other cells in an adult organism than those formed in the organs they themselves come from. At any rate, blood stem cells do not convert to heart muscle cells in a damaged heart, which was previously hoped. This has been shown by a... view more (2004-05-06)

FURTHER STEPS TOWARDS A VACCINE AGAINST HIV
For white blood cells in the human body to be infected by the HIV virus, proteins in the virus must be allowed to interact with a number of different components on the surface of the white blood cell. Ideally anti-HIV preventive therapy or vaccines would prevent several of these interactions taking... view more (1999-03-11)

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