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Estrogen withdrawal results in bone loss, research shows that the Estrogen Receptor has a fundamental role
Professor Lance Lanyon, Principal of The Royal Veterinary College, Karla Lee, Helen Jessop, Rosemary Suswillo, Gul Zaman from the Department of Basic Sciences at The Royal Veterinary College have shown in their research that the Estrogen Receptor has a fundamental role in bone cells by adjusting the bone architecture to match the loads individuals... view more... (2003-07-25)

Previously unseen switch regulates breast cancer response to estrogen
A tiny modification called methylation on estrogen receptors prolongs the life of these growth-driving molecules in breast cancer cells, according to research by scientists at Emory University's Winship Cancer Institute.   view more (2008-05-09)

New biomarker predicts effectiveness of breast cancer drugs
University of Cincinnati (UC) researchers have identified a new way to predict when anti-estrogen drug therapies are inappropriate for patients with hormone-dependent breast cancer.   view more (2006-12-08)

New discovery may help doctors treat infertility
New research suggests that medications commonly referred to as fertility drugs may be ineffective for women who lack a gene called the estrogen receptor beta.   view more (2005-07-21)

Long-term estrogen therapy linked to breast cancer risk
Long-term estrogen therapy may be related to a higher risk of breast cancer among postmenopausal women who have had a hysterectomy, according to an article in the May 8 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.   view more (2006-05-09)

New Genetic Marker for Osteoarthritis - Study Links Estrogen Receptor to Osteoarthritis in Both Men and Women
Among patients with osteoarthritis (OA), a degenerative joint disease, postmenopausal women are the most prevalent. This fact has led to many hypotheses about the role of sex hormones in the cause and effects of OA. Medical researchers at Erasmus MC in the Netherlands recently uncovered a compelling connection between a variation in gene for the... view more... (2003-06-26)

Estrogen protects liver after traumatic injury
Researchers have identified the receptor pathway used by estrogen to decrease liver injury after trauma and hemorrhage.   view more (2007-04-02)

Study identifies potential 'safe period' for hormone replacement use
A new study makes important new findings on the role of hormone use on the risk of breast cancer, confirming that the use of estrogen plus progesterone increases the risk of both ductal and lobular breast cancer far more than estrogen-only; suggesting a two-year "safe" period for the use of estrogen and progesterone; and finding that the... view more... (2009-02-02)

Newly appreciated membrane estrogen receptor important therapeutic target for breast cancer
New research at Rhode Island Hospital has uncovered the biological effects of a novel membrane estrogen receptor, a finding that has potential implications for hormonal therapy for breast cancer.   view more (2009-07-02)

Researchers may have unlocked the mechanisms that silence the estrogen receptor gene alpha during breast cancer
The mechanisms that silence the estrogen receptor gene alpha (ER-α) in certain breast cancer cell lines may be closer to being unlocked.   view more (2007-08-20)

Dual role in breast tissue for a protein involved in leukemia
A protein known to play a role in growth of some types of leukemia appears to have a mixed function in breast cancer development, say researchers from the Lombardi Comprehensive Cancer Center at Georgetown University Medical Center (GUMC).   view more (2009-06-15)

Estrogen curbs appetite in same way as the hormone leptin
Estrogen regulates the brain's energy metabolism in the same way as the hormone leptin, leading the way to a viable approach to tackling obesity in people resistant to leptin.   view more (2007-01-04)

Unique estrogen receptor linked to metastatic breast cancer
Breast cancer awareness month may have passed, but researchers remain focused on the disease with a new study showing that a unique estrogen receptor found in breast cancer tumors is a predictor of tumor size and metastases.   view more (2006-11-01)

Jefferson Scientists Identify Gene Mutation Potentially Involved in Breast Cancer Initiation
Researchers at Jefferson Medical College and the Kimmel Cancer Center at Thomas Jefferson University in Philadelphia and at the Albert Einstein College of Medicine in New York have found evidence suggesting that a mutation in a gene that normally helps block the formation of breast tumors could play a role in the initiation of a major form of... view more... (2006-06-01)

Hormone mix could cut breast cancer risk and treat symptoms of menopause
The right combination of estrogen and a selective estrogen receptor modulator (SERM), which blocks the effects of estrogen in breast tissue, could relieve menopause symptoms and cut breast cancer risk.   view more (2009-10-20)

Improved estrogen reception may sharpen fuzzy memory
Estrogen treatments may sharpen mental performance in women with certain medical conditions, but University of Florida researchers suggest that recharging a naturally occurring estrogen receptor in the brain may also clear cognitive cobwebs.   view more (2008-07-30)

Study uncovers significant functional differences of novel estrogen receptor
Because of these differences, this new estrogen receptor could become an important therapeutic target and may play a further signaling role in other estrogen target tissues, including uterus and prostate tissues.   view more (2006-06-09)

New 'Knock-Out' Gene Model Provides Molecular Clues to Breast Cancer
New insights into the role of estrogen receptor in mammary gland development may help scientists better understand the molecular origin of breast cancer, according to new research from the University of Cincinnati (UC).   view more (2007-09-06)

Variants in three estrogen-related genes linked to Parkinson's disease in women
Mayo Clinic researchers have discovered a possible connection between increased risk for Parkinson's disease and variants in three genes that control estrogen production and activity in the body.   view more (2006-04-05)

Researchers Discover Method in Mice to Restore Tamoxifen Sensitivity in Resistant Breast Cancer
The widely used breast cancer drug tamoxifen (Nolvadex®), which can become less effective over time, might retain its full strength indefinitely if used along with a second drug, according to new research in mice conducted by investigators from the National Cancer Institute (NCI), part of the National Institutes of Health, and their partners.   view more (2006-12-21)
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