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Estrogen Receptor | Estrogen Receptor News, Research and Current Events
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Estrogen withdrawal results in bone loss, research shows that the Estrogen Receptor has a fundamental role
Professor Lance Lanyon, Principal of The Royal Veterinary College, Karla Lee, Helen Jessop, Rosemary Suswillo, Gul Zaman from the Department of Basic Sciences at The Royal Veterinary College have shown in their research that the Estrogen Receptor has a fundamental role in bone cells by adjusting... view more (2003-07-25)
Previously unseen switch regulates breast cancer response to estrogen
A tiny modification called methylation on estrogen receptors prolongs the life of these growth-driving molecules in breast cancer cells, according to research by scientists at Emory University's Winship Cancer Institute. view more (2008-05-09)
New biomarker predicts effectiveness of breast cancer drugs
University of Cincinnati (UC) researchers have identified a new way to predict when anti-estrogen drug therapies are inappropriate for patients with hormone-dependent breast cancer. view more (2006-12-08)
New discovery may help doctors treat infertility
New research suggests that medications commonly referred to as fertility drugs may be ineffective for women who lack a gene called the estrogen receptor beta. view more (2005-07-21)
Long-term estrogen therapy linked to breast cancer risk
Long-term estrogen therapy may be related to a higher risk of breast cancer among postmenopausal women who have had a hysterectomy, according to an article in the May 8 issue of Archives of Internal Medicine, one of the JAMA/Archives journals. view more (2006-05-09)
New Genetic Marker for Osteoarthritis - Study Links Estrogen Receptor to Osteoarthritis in Both Men and Women
Among patients with osteoarthritis (OA), a degenerative joint disease, postmenopausal women are the most prevalent. This fact has led to many hypotheses about the role of sex hormones in the cause and effects of OA. Medical researchers at Erasmus MC in the Netherlands recently uncovered a... view more (2003-06-26)
Estrogen protects liver after traumatic injury
Researchers have identified the receptor pathway used by estrogen to decrease liver injury after trauma and hemorrhage. view more (2007-04-02)
Researchers may have unlocked the mechanisms that silence the estrogen receptor gene alpha during breast cancer
The mechanisms that silence the estrogen receptor gene alpha (ER-α) in certain breast cancer cell lines may be closer to being unlocked. view more (2007-08-20)
Estrogen curbs appetite in same way as the hormone leptin
Estrogen regulates the brain's energy metabolism in the same way as the hormone leptin, leading the way to a viable approach to tackling obesity in people resistant to leptin. view more (2007-01-04)
Unique estrogen receptor linked to metastatic breast cancer
Breast cancer awareness month may have passed, but researchers remain focused on the disease with a new study showing that a unique estrogen receptor found in breast cancer tumors is a predictor of tumor size and metastases. view more (2006-11-01)
Jefferson Scientists Identify Gene Mutation Potentially Involved in Breast Cancer Initiation
Researchers at Jefferson Medical College and the Kimmel Cancer Center at Thomas Jefferson University in Philadelphia and at the Albert Einstein College of Medicine in New York have found evidence suggesting that a mutation in a gene that normally helps block the formation of breast tumors could... view more (2006-06-01)
Study uncovers significant functional differences of novel estrogen receptor
Because of these differences, this new estrogen receptor could become an important therapeutic target and may play a further signaling role in other estrogen target tissues, including uterus and prostate tissues. view more (2006-06-09)
New 'Knock-Out' Gene Model Provides Molecular Clues to Breast Cancer
New insights into the role of estrogen receptor in mammary gland development may help scientists better understand the molecular origin of breast cancer, according to new research from the University of Cincinnati (UC). view more (2007-09-06)
Variants in three estrogen-related genes linked to Parkinson's disease in women
Mayo Clinic researchers have discovered a possible connection between increased risk for Parkinson's disease and variants in three genes that control estrogen production and activity in the body. view more (2006-04-05)
Researchers Discover Method in Mice to Restore Tamoxifen Sensitivity in Resistant Breast Cancer
The widely used breast cancer drug tamoxifen (Nolvadex®), which can become less effective over time, might retain its full strength indefinitely if used along with a second drug, according to new research in mice conducted by investigators from the National Cancer Institute (NCI), part of the... view more (2006-12-21)
Linchpin gene may be useful target for new breast cancer therapies
University of Iowa researchers have discovered a gene that plays a linchpin role in the ability of breast cancer cells to respond to estrogen. The finding may lead to improved therapies for hormone-responsive breast cancers and may explain differences in the effectiveness of current treatments. view more (2007-09-17)
Benefit of chemotherapy in breast cancer depends on estrogen-receptor status
When it comes to chemotherapy treatment for women whose breast cancer has spread to their lymph nodes, the estrogen status of their tumors matters. view more (2006-04-12)
Researchers say estrogen can kill breast cancer cells once fueled by the hormone
Fox Chase Cancer Center researchers say some breast cancer cells once fueled by estrogen can be killed by the same hormone. view more (2005-12-07)
Molecular atlas provides new tool for understanding estrogen-fueled breast cancer
Lurking in unexplored regions of the human genome are thousands of previously unknown on/off switches that may influence how the growth of breast cancer is driven by estrogen. view more (2006-10-03)
Cancer conflict with chemotherapy treatment
Women under the age of forty with breast cancer who are given drugs in addition to lumpectomies or radiotherapy, known as adjuvant chemotherapy, may not be benefiting from these drugs. view more (2007-10-11)
Cholesterol byproduct blocks heart health benefits of estrogen
New findings by UT Southwestern Medical Center researchers show that a byproduct of cholesterol metabolism interferes with the beneficial effects estrogen has on the cardiovascular system, providing a better understanding of the interplay between cholesterol and estrogen in heart disease. view more (2007-09-17)
Low estrogen levels in men linked to increased risk for hip fracture
A new study has found that men with low estrogen levels have an increased risk for future hip fracture, and those with both low estrogen and low testosterone levels have the greatest risk. view more (2006-05-01)
Pituitary hormone implicated in bone loss after menopause
New evidence in the April 21, 2006 Cell challenges the long-standing notion that declining estrogen levels alone lead to osteoporosis after women go through menopause. view more (2006-04-21)
Gene expression test reveals ER and HER-2 status of breast tumors
Two critical characteristics of breast cancer that are important to treatment can be identified by measuring gene expression in the tumor, a research team led by scientists at The University of Texas M. D. Anderson Cancer Center reports in Lancet Oncology online. view more (2007-02-15)
Study of early estrogen's effect on heart disease similar to WHI findings
Researchers in The Department of Obstetrics, Gynecology & Reproductive Sciences at Yale have launched the Kronos Early Estrogen Prevention Study (KEEPS), which will further understanding of the possible beneficial effects on the heart and arteries and/or quality of life in recently menopausal... view more (2006-03-01)
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