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Scientists Learn the Origin of Rogue B Cells
Doctors have long wondered why, in some people, the immune system turns against parts of the body it is designed to protect, leading to autoimmune disease.   view more (2007-02-08)

Study shows liver an excellent target for cancer gene therapy using viral vectors
A featured paper in the February 14 issue of Nature Cancer Gene Therapy demonstrates that cancer cells in the liver are excellent targets for gene therapy using adenoviral vectors, based upon a fundamental new understanding of the differences between cancerous and normal liver cells.   view more (2007-02-15)

Unexpected features of anthrax toxin may lead to new types of therapies
Surprising new insights about the acid pH levels required for anthrax toxin to invade the cells of the body may help accelerate development of medications for the treatment of anthrax, a disease caused by a spore-forming bacterium.   view more (2005-08-30)

Cortisol and fatty liver: Researchers find cause of severe metabolic disorders
A healthy body stores fat in the form of so-called triglycerides in specialized fatty tissue as an energy reserve. Under certain conditions the delicate balance of the lipid metabolism gets out of control and fat is accumulated in the liver, leading to the dreaded fatty liver.   view more (2008-09-10)

Exercise reduces risk of heart disease in postmenopausal women
Aerobic exercise significantly decreased the chemical imbalances that can lead to heart disease and stroke in postmenopausal women according to a study in the spring issue of the Journal of Women and Aging.   view more (2008-03-18)

Study identifies source of fever
With the finding that fever is produced by the action of a hormone on a specific site in the brain, scientists have answered a key question as to how this adaptive function helps to protect the body during bacterial infection and other types of illness.   view more (2007-08-06)

LIAI scientists make important finding on cytomegalovirus transmission
Researchers at the La Jolla Institute for Allergy & Immunology have shown that cytomegalovirus (CMV) in the salivary glands can be reduced - and in some cases eliminated - through the use of antibodies to enhance the disease-fighting power of the immune system.   view more (2007-05-11)

Researchers identify the cells and receptor for sensing sour taste
In the last seven years, Howard Hughes Medical Institute researcher Charles S. Zuker and Nicholas J.P. Ryba at the National Institutes of Health have worked together to identify the cells, receptors and signaling mechanisms for three of the five tastes humans can sense - sweet, bitter, and umami... view more (2006-08-24)

Breast cancer is more aggressive in African-American women
African American women are diagnosed with breast cancer at a younger age and have larger tumors and more lymph node involvement than Caucasian women, a Yale School of Medicine researcher reported today.   view more (2007-10-30)

A new relationship between brain derived neurotrophic factor and inflammatory signaling
In the October 14th edition of Science Signaling researchers at Boston University School of Medicine (BUSM), The Children's Hospital of Philadelphia/University of Pennsylvania School of Medicine and The University of Colorado Denver School of Medicine have shown that the development of epilepsy in... view more (2008-10-23)

Grabbing addiction by the tail
Canadian scientists have developed some clever molecular trickery that is helping to reduce the drug cravings of addicted rats. One of the problems in addiction is that neurons in some parts of the brain lose glutamate receptors from the cell surface, and those receptors are important for... view more (2005-11-28)

Researchers create first model for retina receptors
A team of scientists at the University of Oklahoma Health Sciences Center has created the first genetic research model for a microscopic part of the eye that when missing causes blindness. The research appears in a recent issue of the Journal of Biological Chemistry.    view more (2008-10-01)

St. Jude study shows how T cell's machinery dials down autoimmunity
A St. Jude Children's Research Hospital study shows that T cells, the body's master immune regulators, do not use simple on/off switches to govern the cellular machinery that regulates their development and function. Rather, they possess sophisticated molecular controls that enable them to adjust... view more (2008-05-13)

Chemotherapy-induced anemia increases risk of local breast cancer recurrence
Patients with breast cancer who developed anemia during chemotherapy had nearly three times the risk of local recurrence as those who did not, according to a study published in the April 1 issue of Clinical Cancer Research, a journal of the American Association for Cancer Research.   view more (2008-04-01)

Scripps Research scientists shed new light on how antibodies fight HIV
By furthering scientists' understanding of the molecular mechanisms that separate the minority of successful HIV antibodies from the majority of ineffective antibodies, the work may have implications for future attempts to design an HIV vaccine.   view more (2007-09-07)

Getting to the roots of hair loss
A healthy individual loses around a hundred hairs a day. Nothing to worry about as long as they are constantly replaced and the losses occur evenly around the whole scalp.   view more (2008-02-25)

Testosterone Therapy Improves Sexual Function in Post-Menopausal Women
The addition of testosterone to hormone therapy in women after menopause enhances their sexual function. However, it may also reduce HDL cholesterol (the "good" cholesterol) in women, according to a systematic review of current evidence.   view more (2005-10-24)

Hormone helps mice 'hibernate,' survive starvation
A key hormone enables starving mice to alter their metabolism and "hibernate" to conserve energy, revealing a novel molecular target for drugs to treat human obesity and metabolic disorders, UT Southwestern Medical Center researchers have found.   view more (2007-06-06)

Targeted tumor therapy: When antagonists do the better job
Targeted tumor therapy lobs toxic payloads directly into tumors to destroy cancer cells while leaving normal cells unharmed.   view more (2006-10-23)

Long-term smoking is associated with up to 40 percent increased risk of breast cancer
Older women who have smoked for 11 or more "pack years" - the lifetime equivalent of a pack a day for at least 11 years - face a 30 percent to 40 percent increased risk of developing breast cancer as compared to women who've never smoked.   view more (2005-09-28)

New study: Pine bark significantly reduces endometriosis
There's promising hope for women who suffer from endometriosis, one of the most common causes of infertility and pelvic pain.   view more (2007-03-08)

Halting retrieval of drug-associated memories may prevent addiction relapse
Disrupting the brain's retrieval of drug-associated memories may prevent relapse in drug addiction, according to new research in the August 13 issue of The Journal of Neuroscience.   view more (2008-08-13)

Reining in cancer - first laboratory study to show that combining novel targeted therapiesmay keep cancer cells under control
A team of Italian researchers has demonstrated in the laboratory for the first time that combining two of the newest anti-cancer targeted agents may produce a powerful new combination against breast cancer - and possibly many other cancers as well. Their findings are reported (Thursday 24 January)... view more (2002-01-21)

Aspirin and atherosclerosis
Aspirin has become one of the most widely used medications in the world, owing to its ability to reduce pain, fevers, inflammation, and blood clotting.   view more (2008-09-23)

Fresh use of targeted therapy advances treatment of early HER2-positive breast cancer
The news that the world's first targeted therapy, trastuzumab (Herceptin), is now available for many women with early-stage HER2-positive breast cancer "highlights a truly significant advance in the management of breast cancer," says Edith Perez, M.D., director of Mayo Clinic's Breast... view more (2006-11-20)
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