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Estrogen Receptor News | Estrogen Receptor Current Events
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Findings Point to Molecular 'Achilles Heel' for Half of Breast Cancer Tumors
Researchers at Lombardi Comprehensive Cancer Center at Georgetown University Medical Center have shown why a protein known as cyclin D1 may be the Achilles heel for breast tumors that are estrogen receptor positive (ER+) − which is the most common type of breast cancer.   view more (2008-01-16)

Ultra low-dose estrogen shown safe for post-menopausal women
A study led by researchers at the San Francisco VA Medical Center has shown that extremely low doses of estrogen had no ill effects on the cognitive abilities or general health of older women over the course of two years.   view more (2006-07-17)

Estrogen plays different role during stress in black and white teens
Estrogen seems to play a different role during stress in black and white girls, a difference that may help explain higher cardiovascular disease rates in blacks, researchers have found.   view more (2006-06-26)

Estrogen-progestin menopausal hormone therapy and risk of lobular and tubular breast cancer
Estrogen-progestin menopausal hormone therapy is associated with a more than two-fold higher relative risk of developing lobular cancer or tubular cancer than of developing ductal cancer.   view more (2006-02-17)

A Novel Strategy for Combating Aids-Related Fungal Infections
Research at the Sir William Dunn School of Pathology has identified Dectin-1 as the beta-glucan receptor on immune cells. This finding may be of use in the prophylactic prevention of a variety of infections, especially in surgical patients, and in the treatment of cancer. The identification of... view more (2004-10-08)

Complex Changes in the Brain's Vascular System Occur after Menopause
Many women experience menopausal changes in their body including hot flashes, moodiness and fatigue, but the changes they don't notice can be more dangerous.   view more (2008-06-17)

New Cause of Tamoxifen Resistance in Breast Cancer Cells Discovered at Lombardi
When a woman receives a breast cancer diagnosis her entire life may change in the blink of an eye. But the nature of that change is governed by the smallest alterations that take place within the proteins of the tumor cells, determining what treatments she can pursue with a hope of cure and those... view more (2007-08-13)

Study finds hereditary link to premenstrual depression
A specific genetic variation may be tied to an increased risk for severe premenstrual depression, scientists at the University of North Carolina at Chapel Hill and the National Institute of Mental Health have found.   view more (2007-07-18)

First significant genetic finding in severe PMS, or PMDD
The first significant genetic finding in premenstrual dysphoric disorder (PMDD) has now been reported. PMDD is a very severe form of the more commonly known premenstrual syndrome, or PMS.   view more (2007-10-03)

Researchers identify cancer preventive properties in common vitamin supplement
Early laboratory research has shown that resveratrol, a common dietary supplement, suppresses the abnormal cell formation that leads to most types of breast cancer, suggesting a potential role for the agent in breast cancer prevention.   view more (2008-07-07)

Blood cholesterol levels predict risk of heart disease due to hormone therapy
A new analysis of a subgroup of participants in the Women's Health Initiative (WHI) hormone therapy clinical trials suggests that healthy, postmenopausal women whose blood cholesterol levels are normal or lower are not at increased, short-term risk for heart attack when taking hormone therapy.   view more (2008-05-27)

Studies Examine Menopausal Hormone Therapy and Risk of Breast Cancer Recurrence
The doses of estrogen and progestogen used in menopausal hormone therapy may be related to the risk of breast cancer recurrence, according to a new study in the April 6 issue of the Journal of the National Cancer Institute. In 1997, two randomized trials, the Hormonal Replacement Therapy-Is It... view more (2005-04-06)

A diagnosis of triple-negative breast cancer doesn't always mean cancer spread
Triple-negative breast cancers are a heterogeneous group and may not always be associated with lymph node spread, a new study shows.   view more (2008-04-14)

Dartmouth researchers show effects of low dose arsenic on development
A team of Dartmouth Medical School (DMS) researchers has determined that low doses of arsenic disrupt the activity of a hormone critical in development.   view more (2007-11-15)

Stoned sea-squirts
The psychoactive ingredient of the drug cannabis exerts its effects on the human brain by activating proteins known as cannabinoid receptors. Dr. Maurice Elphick of Queen Mary, University of London has uncovered the first evidence that cannabinoid receptors may not be unique to humans and other... view more (2004-03-31)

Extracts of catfish caught in polluted waters cause breast cancer cells to multiply
Exposing estrogen-sensitive breast cancer cells to extracts of channel catfish caught in areas with heavy sewer and industrial waste causes the cells to multiply.   view more (2007-11-07)

Growth hormone is made in the brain, report scientists
Scientists have found that growth hormone, a substance that is used for body growth, is produced in the brain, according to an article published in this week's Proceedings of the National Academy of Sciences.   view more (2006-03-28)

How DDT metabolite disrupts breast cancer cells
Research has shown that the main metabolite of the insecticide DDT could be associated with aggressive breast cancer tumours, but there has been no explanation for this observation to date. Now a report published in the open access journal Breast Cancer Research shows how DDT could act to disrupt... view more (2008-02-14)

1 in 5 early-stage breast cancer patients may not follow hormonal therapy plan
Postmenopausal women with early-stage, hormone-sensitive breast cancer have a lower risk of disease recurrence when their treatment includes a new class of hormone therapy drugs, yet one out five women prescribed the drugs may not take them regularly.   view more (2006-12-18)

Cancer risk slightly higher for women in discontinued hormone treatment trial
A follow up study of participants in the Women's Health Initiative (WHI) clinical trial led by a University of North Carolina at Chapel Hill researcher has found that women who were taking the combined hormone therapy of estrogen plus progestin may have an increased risk of cancer since the... view more (2008-03-05)

Researchers identify taste receptor responsible for caffeine detection
By studying how taste-receptor mutations impact fruit fly behavior, researchers have identified a taste receptor responsible for the detection of caffeine, a bitter compound known to activate certain taste-receptor neurons, as well as impact various aspects of physiology.   view more (2006-09-19)

Fewer wrinkles and firmer skin linked to earlier use of estrogen therapy
Long-term hormone estrogen therapy used earlier in menopause is associated with fewer wrinkles and less skin rigidity in postmenopausal women, Yale School of Medicine researchers report in the August issue of Fertility and Sterility.   view more (2005-08-29)

Scientists breed special rats to learn more about hypertension
Scientists at Wake Forest University School of Medicine have created a better research rat - the first to enable them to study how declining estrogen after menopause can affect hypertension, heart failure and kidney damage.   view more (2005-09-23)

Mechanism of black cohosh versus hot flashes revealed
The natural herb black cohosh is commonly used by women to treat menopausal symptoms such as hot flashes, but the molecular mechanisms underlying its action have eluded scientists - until now.   view more (2006-12-26)

Letrozole following tamoxifen may benefit women with breast cancer
Switching to the drug letrozole following 5 years of treatment with tamoxifen reduces the risk of hormone-dependent breast cancer recurrence, but not overall survival, among postmenopausal women.   view more (2005-09-07)
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