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Estrogen Receptor Current Events | Estrogen Receptor News | 4
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Scientists breed special rats to learn more about hypertension
Scientists at Wake Forest University School of Medicine have created a better research rat - the first to enable them to study how declining estrogen after menopause can affect hypertension, heart failure and kidney damage.   view more (2005-09-23)

Mechanism of black cohosh versus hot flashes revealed
The natural herb black cohosh is commonly used by women to treat menopausal symptoms such as hot flashes, but the molecular mechanisms underlying its action have eluded scientists - until now.   view more (2006-12-26)

Letrozole following tamoxifen may benefit women with breast cancer
Switching to the drug letrozole following 5 years of treatment with tamoxifen reduces the risk of hormone-dependent breast cancer recurrence, but not overall survival, among postmenopausal women.   view more (2005-09-07)

Breast cancer treatment resistance linked to signaling pathway
Activation of the Src signaling pathway may cause resistance to standard medical treatment in some patients with breast cancer, and inhibition of this pathway holds the potential to overcome that resistance, according to data presented here at the American Association for Cancer Research Molecular... view more (2008-09-23)

Polluted prey causes wild birds to change their tune
Considerable attention has been paid to the effects of endocrine disrupting chemicals in aquatic environments, but rather less attention has been given to routes of contamination on land.   view more (2008-02-27)

Effects of progesterone on Alzheimer's disease
The first study on progesterone and Alzheimer's disease has found no clear preventive benefit for the widely prescribed hormone in an animal model.   view more (2007-11-28)

Menopausal complaints in women -and men!
Men can also evince menopausal complaints. As many as one third of a group of men over the age of 55 reported that they experienced sweating and hot flashes, according to a researcher at Linköping University in Sweden. Another member of the same research team has found that acupuncture often... view more (2002-12-20)

Common pesticide may reduce fertility in women
Methoxychlor (MXC), a common insect pesticide used on food crops, may interfere with proper development and function of the reproductive tract, leading to reduced fertility in women, researchers at Yale School of Medicine write in the August issue of Endocrinology.   view more (2005-09-13)

New computational technique can predict drug side effects
Early identification of adverse effects of drugs before they are tested in humans is crucial in developing new therapeutics, as unexpected effects account for a third of all drug failures during the development process.   view more (2007-12-12)

Estrogen relieves psychotic symptoms in women with schizophrenia
When combined with antipsychotic medications, the estrogen estradiol appears to be a useful treatment in women with schizophrenia, according to a report in the August issue of Archives of General Psychiatry, one of the JAMA/Archives journals.   view more (2008-08-05)

New Study Finds Adverse Effects Of Estrogen Replacement Therapy (ERT) Are Related To The Dose
Recent clinical trials indicate that estrogen replacement therapy (ERT) may increase the risk of cardiovascular diseases. A new study in mice has examined whether adverse effects of ERT are related to the doses used.   view more (2008-04-08)

The dietary supplement genistein can undermine breast cancer treatment
Women taking aromatase inhibitors to treat breast cancer or prevent its recurrence should think twice before also taking a soy-based dietary supplement, researchers report.   view more (2008-09-24)

High levels of estrogen associated with breast cancer recurrence
Women whose breast cancer came back after treatment had almost twice as much estrogen in their blood than did women who remained cancer-free - despite treatment with anti-estrogen drugs in a majority of the women -according to researchers in a study published in the March issue of Cancer... view more (2008-03-06)

Study finds estrogen therapy gives aging brain cells a boost
Cyclical, long-term estrogen injections protected brain cells from age-related deterioration, according to a new study conducted at Mount Sinai School of Medicine.   view more (2007-06-26)

A novel model to pinpoint human androgen receptor targets developed
A novel computational model to pinpoint androgen receptor targets within the human genome was recently reported.   view more (2005-11-01)

Ovary removal surgery elevates risk for dementia
Mayo Clinic researchers have found that ovariectomy, surgical removal of a woman's ovaries, raises her risk of developing dementia or cognitive impairment. Risk is especially increased if a woman has her ovaries removed at a young age.   view more (2006-04-06)

Effect on Breast Tumors of DNA Alternations in 3 Genes Described
Cancer epidemiologists at the University at Buffalo have identified specific genes that are most likely to become cancer promoters when exposed to a process called DNA promoter hypermethylation.   view more (2007-05-17)

Hamilton College Researchers Discover New Molecules with the Potential to Treat Breast Cancer
Hamilton College researchers have identified molecules that have been shown to be effective in the fight against breast cancer.    view more (2007-05-07)

Some nonhormonal therapies may offer relief from hot flashes, but with possible adverse effects
A meta-analysis of previously published studies examining the use of nonhormonal therapies for treating menopausal hot flashes finds that some therapies are effective, but less so than estrogen, and have possible adverse effects that may restrict their use.   view more (2006-05-03)

Breathe deep: Which patients could benefit from inhaled steroids in cystic fibrosis?
A specific variation in the glucocorticoid receptor gene is associated with lung disease progression in cystic fibrosis, research published this week in the online open access journal Respiratory Research reveals.   view more (2007-11-29)

Inflammatory reaction drives hormone resistance in cancer, study suggests
In the February 10, 2006 Cell, researchers report new evidence to explain why prostate cancer and other hormone-dependent cancers may become resistant to hormone therapies.   view more (2006-02-10)

Help for bleeding hearts: new research links a third protein to blood-clotting disorders
Studying receptors on the surface of blood platelets, sticky cells that cause blood to clot, has given one Rockefeller researcher new insight into potential causes and treatments for certain cardiovascular diseases.   view more (2006-04-20)

Breast cancer drugs may slow growth of lung cancer
A few years ago researchers discovered that, much like breast tumors, some lung tumors also thrive on estrogen. Now a medical student conducting research on a Howard Hughes Medical Institute (HHMI) fellowship and colleagues have managed to stop the growth of human lung cancer cells in mice with a... view more (2005-12-15)

Decrease in breast cancer incidence linked to drop in hormone replacement
A special report in the April 19, 2007 edition of The New England Journal of Medicine concludes that the sharp decline in breast-cancer incidence in 2003, followed by a relative stabilization at a lower rater in 2004, is most likely related to the first report of the Women's Health Initiative (WHI)... view more (2007-04-19)

Newer chemotherapies improve outcomes for some types of breast cancer
An updated analysis of findings from three major consecutive clinical trials of breast cancer treatment conducted over the past twenty years indicates that women who have breast cancer with lymph node involvement and estrogen-receptor negative tumors have a lower rate of recurrence and risk of... view more (2006-04-12)
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