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Protein marker associated with positive outcome in invasive breast cancer
Researchers at Sunnybrook and Women's College Health Sciences Centre have found a new protein marker linked to positive outcome in patients with breast cancer.   view more (2005-11-16)

Research shows certain metabolites responsible for initiating breast and prostate cancer
Cancer researchers have discovered that metabolites of natural estrogens can react with deoxyribonucleic acid (DNA) to cause specific damage that initiates the series of events leading to breast, prostate and other human cancers.   view more (2006-03-29)

Mitochondria play role in pathogenesis of AD and estrogen-induced neuroprotection
As the major source of free radicals in cells, mitochondria contribute to the high levels of oxidative stress believed to play a role in the pathogenesis of Alzheimer's disease.   view more (2008-04-07)

Effect of hormone therapy on risk of heart disease may vary by age and years since menopause
Secondary analyses of findings from the Womenˇ¦s Health Initiative (WHI) suggest that women who begin hormone therapy within 10 years of menopause may have less risk of coronary heart disease (CHD) due to hormone therapy than women farther from menopause.   view more (2007-04-04)

Estrogen therapy in younger postmenopausal women linked to less plaque in arteries
New results from a substudy of the Women's Health Initiative (WHI) Estrogen-Alone Trial show that younger postmenopausal women who take estrogen-alone hormone therapy have significantly less buildup of calcium plaque in their arteries compared to their peers who did not take hormone therapy.   view more (2007-06-21)

Dietary calcium is better than supplements at protecting bone health
Women who get most of their daily calcium from food have healthier bones than women whose calcium comes mainly from supplemental tablets.   view more (2007-06-20)

Scientists find one reason why bladder cancer hits more men
Scientists have discovered one of the reasons why bladder cancer is so much more prevalent in men than women: A molecular receptor or protein that is much more active in men than women plays a role in the development of the disease. The finding could open the door to new types of treatment with the... view more (2007-04-23)

Postmenopausal hormone therapy and coronary disease -- the truth of the matter
With each new publication of coronary artery disease (CAD) data from the Women's Health Initiative (WHI) study, the inevitable reaction is "Why on earth did the WHI investigators claim in 2002-2004 that postmenopausal hormone therapy has deleterious effects on the risk for CAD, when, from the... view more (2007-06-21)

Active lifestyle reduces risk of invasive breast cancer
Six or more hours per week of strenuous recreational activity may reduce the risks of invasive breast cancer by 23 percent, according to researchers from the University of Wisconsin Paul P. Carbone Comprehensive Cancer Center (UWCCC).   view more (2007-02-16)

Scientists learn role of oxidative stress in estrogen-related bone loss
Scientists have discovered new information about an immune pathway in mice that explains how oxidative stress that results from acute estrogen deficiency leads to the loss of bone.   view more (2007-09-11)

Gene variations contribute to aggression and anger in women
Ever wonder why some women seem to be more ill-tempered than others? University of Pittsburgh researchers have found that behaviors such as anger, hostility and aggression may be genetic, rooted in variations in a serotonin receptor gene.   view more (2007-03-12)

Neurons use chemical 'chords' to shape signaling
Researchers have discovered that neurons can use two different neurotransmitters that target the same receptor on a receiving neuron to shape the transmission of a nerve impulse.   view more (2008-02-28)

Scientists determine structure of brain receptor implicated in epilepsy and PMT
Scientists funded by the Biotechnology and Biological Sciences Research Council (BBSRC) have published new research in the journal Molecular Pharmacology identifying the structure of a receptor in the brain implicated in conditions such as epilepsy and pre-menstrual tension. The same receptor has... view more (2008-03-10)

Vitamin D and breast cancer risk
A connection between vitamin D level and the risk of developing breast cancer has been implicated for a long time, but its clinical relevance had not yet been proven.   view more (2008-04-21)

Nicotinic receptors may be important targets for treatment of multiple addictions
For years, scientists have known that some people are biologically more susceptible to drug addiction than others, but they have only been able to speculate why.   view more (2007-08-16)

Nuclear Medicine Imaging Allows Immediate Prediction of Advanced Breast Cancer Patients' Response to Hormonal Treatment
Innovative use of somatostatin receptor scintigraphy (SRS), a nuclear medicine imaging technique looking at how the body functions at the molecular level, may provide near immediate selection of breast cancer patients for endocrine therapy and offers a new tool in fighting the disease.   view more (2006-01-20)

IMS reaction to report on breast cancer incidence in 2003 in US
A special report in the April 19 issue of the New England Journal of Medicine [1] brings initial analysis of data from the National Cancer Institute's Surveillance, Epidemiology and End Result (SEER) registries, showing that the incidence of breast cancer in women in the US fell by 6.7% in 2003,... view more (2007-04-19)

Crucial Factors in Lymphoma Development and Survival Discovered
Researchers at National Jewish Medical and Research Center have discovered an important factor in the development of B-cell lymphomas, one of the fastest growing forms of cancer.   view more (2008-06-24)

Mayo Clinic study finds two genes predict outcome for breast cancer patients
The 2-gene expression profile of HOXB13 and IL17BR in a woman's breast cancer predicts risk of recurrence in node-negative patients treated with tamoxifen.   view more (2006-04-03)

Some antipsychotic drugs may be missing their mark
Drugs that treat depression, schizophrenia and other psychotic conditions and that target a particular protein on brain cells might not be triggering the most appropriate response in those cells, new research suggests.   view more (2008-01-02)

New Model Shows Gender Differences in High Blood Pressure, Jefferson Scientists Find
Researchers at Jefferson Medical College have implicated a protein called GRK5 as having an important role behind essential hypertension, which affects more than 65 million Americans.   view more (2005-10-06)

Selective marker found to indicate aggressive form of breast cancer
Researchers have linked a structural protein called nestin to a particularly deadly form of breast cancer, identifying a new biomarker that could lead to earlier detection and better treatment.   view more (2007-01-15)

Targeting nerve growth factor may cure liver cancer
Nerve growth factor (NGF), as the name says, is an essential peptide factor for the growth and differentiation of neuronal cells. Therefore we can imagine that this growth factor is important for the nervous system including brain.   view more (2007-09-19)

Integrins as receptors give insight into rotavirus and diarrhea
Eleven years ago, Dr. Mary Estes of Baylor College of Medicine and her colleagues discovered the first viral enterotoxin, rotavirus NSP4, a toxic protein that affects the intestines, causing diarrhea.   view more (2008-07-01)

UVa Scientists Hot on Trail of Therapies for Deadly Lung Failure
Researchers at the University of Virginia Health System have identified a molecular target, or receptor, for potential drugs to treat acute respiratory distress syndrome (ARDS), a sudden and life-threatening failure of the lung.   view more (2006-02-22)
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