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Estrogen Receptor Current Events | Estrogen Receptor News | 7

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Breast cancer etiology may vary by subtype
Women's reproductive and lifestyle characteristics can be linked to different invasive breast cancer subtypes. Data on 2544 breast cancer cases, presented in the open access journal Breast Cancer Research, suggests that traditional risk factors for development of the condition are associated with different kinds of tumor.   view more (2009-05-22)

A novel model to pinpoint human androgen receptor targets developed
A novel computational model to pinpoint androgen receptor targets within the human genome was recently reported.   view more (2005-11-01)

Ovary removal surgery elevates risk for dementia
Mayo Clinic researchers have found that ovariectomy, surgical removal of a woman's ovaries, raises her risk of developing dementia or cognitive impairment. Risk is especially increased if a woman has her ovaries removed at a young age.   view more (2006-04-06)

Effect on Breast Tumors of DNA Alternations in 3 Genes Described
Cancer epidemiologists at the University at Buffalo have identified specific genes that are most likely to become cancer promoters when exposed to a process called DNA promoter hypermethylation.   view more (2007-05-17)

Hamilton College Researchers Discover New Molecules with the Potential to Treat Breast Cancer
Hamilton College researchers have identified molecules that have been shown to be effective in the fight against breast cancer.    view more (2007-05-07)

Some nonhormonal therapies may offer relief from hot flashes, but with possible adverse effects
A meta-analysis of previously published studies examining the use of nonhormonal therapies for treating menopausal hot flashes finds that some therapies are effective, but less so than estrogen, and have possible adverse effects that may restrict their use.   view more (2006-05-03)

Breathe deep: Which patients could benefit from inhaled steroids in cystic fibrosis?
A specific variation in the glucocorticoid receptor gene is associated with lung disease progression in cystic fibrosis, research published this week in the online open access journal Respiratory Research reveals.   view more (2007-11-29)

Breast cancer drugs may slow growth of lung cancer
A few years ago researchers discovered that, much like breast tumors, some lung tumors also thrive on estrogen. Now a medical student conducting research on a Howard Hughes Medical Institute (HHMI) fellowship and colleagues have managed to stop the growth of human lung cancer cells in mice with a class of breast cancer drugs called aromatase... view more... (2005-12-15)

Inflammatory reaction drives hormone resistance in cancer, study suggests
In the February 10, 2006 Cell, researchers report new evidence to explain why prostate cancer and other hormone-dependent cancers may become resistant to hormone therapies.   view more (2006-02-10)

Birth control has long-term effect on hormone exposure
Researchers at Wake Forest University School of Medicine may be one step closer to understanding why past oral contraceptive use dramatically lowers the risk of ovarian and uterine cancers later in life.   view more (2008-10-21)

Decrease in breast cancer incidence linked to drop in hormone replacement
A special report in the April 19, 2007 edition of The New England Journal of Medicine concludes that the sharp decline in breast-cancer incidence in 2003, followed by a relative stabilization at a lower rater in 2004, is most likely related to the first report of the Women's Health Initiative (WHI) and the ensuing drop in hormone-replacement... view more... (2007-04-19)

Help for bleeding hearts: new research links a third protein to blood-clotting disorders
Studying receptors on the surface of blood platelets, sticky cells that cause blood to clot, has given one Rockefeller researcher new insight into potential causes and treatments for certain cardiovascular diseases.   view more (2006-04-20)

Estrogen use lowered one risk factor for heart disease among some younger postmenopausal women
A follow-up study to the federally funded Women's Health Initiative should help allay one concern in a subset of women in their 50s who are considering taking estrogen to relieve hot flashes.   view more (2007-06-21)

Newer chemotherapies improve outcomes for some types of breast cancer
An updated analysis of findings from three major consecutive clinical trials of breast cancer treatment conducted over the past twenty years indicates that women who have breast cancer with lymph node involvement and estrogen-receptor negative tumors have a lower rate of recurrence and risk of death with treatment with newer chemotherapies.   view more (2006-04-12)

Estrogens as antioxidants - reducing heart disease in younger postmenopausal women
HRT could be used to protect younger postmenopausal women from heart disease. An article published in the journal Lipids in Health and Disease shows that estrogens commonly used in HRT reduce the build up of harmful oxidised lipoproteins, which can lead to heart disease, by acting as antioxidants.   view more (2003-07-04)

Hormones may affect how brain listens, Emory study finds
From zebra fish to humans, reproductive hormones govern behavioral responses to courtship signals. A new Emory University study conducted in songbirds suggests that hormones may also modulate the way the auditory system processes courtship signals.   view more (2006-05-03)

Variant of vitamin D receptor gene linked to melanoma risk
A new analysis indicates an association between a gene involved in vitamin D metabolism and skin cancer. Published in the November 1, 2008 issue of CANCER, a peer-reviewed journal of the American Cancer Society, the study suggests that individuals with certain variants in a vitamin D-related gene, called BsmI, may be at an increased risk of... view more... (2008-09-22)

More older women with early stage breast cancer choose chemotherapy, GUMC researchers say
A new study examining treatment decision-making by older women with early stage breast cancer shows that 45 percent of women would choose to get chemotherapy after surgery -- a figure higher than the national average of women getting the additional treatment.   view more (2009-05-15)

Study finds it pays to be heart smart if considering hormone therapy
A research study has found that a simple blood test may indicate whether post-menopausal hormone therapies present an elevated risk of a heart attack.   view more (2008-05-22)

Suspicion lingers over bisphenol A and breast cancer
Bisphenol A, a common industrial chemical claimed to speed the growth of human breast and ovarian cancers, retains its carcinogenic properties even after being modified by body processes.   view more (2006-08-28)
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