Estrogen Receptor Current Events | Estrogen Receptor News | 8
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Protein marker associated with positive outcome in invasive breast cancer Researchers at Sunnybrook and Women's College Health Sciences Centre have found a new protein marker linked to positive outcome in patients with breast cancer. view more (2005-11-16)
Research shows certain metabolites responsible for initiating breast and prostate cancer Cancer researchers have discovered that metabolites of natural estrogens can react with deoxyribonucleic acid (DNA) to cause specific damage that initiates the series of events leading to breast, prostate and other human cancers. view more (2006-03-29)
Mitochondria play role in pathogenesis of AD and estrogen-induced neuroprotection As the major source of free radicals in cells, mitochondria contribute to the high levels of oxidative stress believed to play a role in the pathogenesis of Alzheimer's disease. view more (2008-04-07)
Breast tenderness during hormone replacement therapy linked to elevated cancer risk Women who developed new-onset breast tenderness after starting estrogen plus progestin hormone replacement therapy were at significantly higher risk for developing breast cancer than women on the combination therapy who didn't experience such tenderness, according to a new UCLA study. view more (2009-10-13)
Effect of hormone therapy on risk of heart disease may vary by age and years since menopause Secondary analyses of findings from the Womenˇ¦s Health Initiative (WHI) suggest that women who begin hormone therapy within 10 years of menopause may have less risk of coronary heart disease (CHD) due to hormone therapy than women farther from menopause. view more (2007-04-04)
Estrogen therapy in younger postmenopausal women linked to less plaque in arteries New results from a substudy of the Women's Health Initiative (WHI) Estrogen-Alone Trial show that younger postmenopausal women who take estrogen-alone hormone therapy have significantly less buildup of calcium plaque in their arteries compared to their peers who did not take hormone therapy. view more (2007-06-21)
Dietary calcium is better than supplements at protecting bone health Women who get most of their daily calcium from food have healthier bones than women whose calcium comes mainly from supplemental tablets. view more (2007-06-20)
Common herbicides and fibrates block nutrient-sensing receptor found in gut and pancreas According to new research from the Monell Center and the Mount Sinai School of Medicine, certain common herbicides and lipid-lowering fibrate drugs act in humans to block T1R3, a nutrient-sensing taste receptor also present in intestine and pancreas. view more (2009-10-12)
Postmenopausal hormone therapy and coronary disease -- the truth of the matter With each new publication of coronary artery disease (CAD) data from the Women's Health Initiative (WHI) study, the inevitable reaction is "Why on earth did the WHI investigators claim in 2002-2004 that postmenopausal hormone therapy has deleterious effects on the risk for CAD, when, from the beginning, they were aware of the importance of... view more... (2007-06-21)
Gap junction protein vital to successful pregnancy, researchers find Researchers studying a critical stage of pregnancy - implantation of the embryo in the uterus - have found a protein that is vital to the growth of new blood vessels that sustain the embryo. Without this protein, which is produced in higher quantities in the presence of estrogen, the embryo is unlikely to survive. view more (2008-09-11)
Scientists find one reason why bladder cancer hits more men Scientists have discovered one of the reasons why bladder cancer is so much more prevalent in men than women: A molecular receptor or protein that is much more active in men than women plays a role in the development of the disease. The finding could open the door to new types of treatment with the disease. view more (2007-04-23)
Active lifestyle reduces risk of invasive breast cancer Six or more hours per week of strenuous recreational activity may reduce the risks of invasive breast cancer by 23 percent, according to researchers from the University of Wisconsin Paul P. Carbone Comprehensive Cancer Center (UWCCC). view more (2007-02-16)
Scientists learn role of oxidative stress in estrogen-related bone loss Scientists have discovered new information about an immune pathway in mice that explains how oxidative stress that results from acute estrogen deficiency leads to the loss of bone. view more (2007-09-11)
Matrix fragments trigger fatal excitement Shredded extracellular matrix (ECM) is toxic to neurons. Chen et al. reveal a new mechanism for how ECM demolition causes brain damage. The study will appear in the December 29, 2008 issue of The Journal of Cell Biology (www.jcb.org). view more (2008-12-30)
Gene variations contribute to aggression and anger in women Ever wonder why some women seem to be more ill-tempered than others? University of Pittsburgh researchers have found that behaviors such as anger, hostility and aggression may be genetic, rooted in variations in a serotonin receptor gene. view more (2007-03-12)
Neurons use chemical 'chords' to shape signaling Researchers have discovered that neurons can use two different neurotransmitters that target the same receptor on a receiving neuron to shape the transmission of a nerve impulse. view more (2008-02-28)
Vitamin D and breast cancer risk A connection between vitamin D level and the risk of developing breast cancer has been implicated for a long time, but its clinical relevance had not yet been proven. view more (2008-04-21)
Scientists determine structure of brain receptor implicated in epilepsy and PMT Scientists funded by the Biotechnology and Biological Sciences Research Council (BBSRC) have published new research in the journal Molecular Pharmacology identifying the structure of a receptor in the brain implicated in conditions such as epilepsy and pre-menstrual tension. The same receptor has also been reported to be highly sensitive to... view more... (2008-03-10)
Nicotinic receptors may be important targets for treatment of multiple addictions For years, scientists have known that some people are biologically more susceptible to drug addiction than others, but they have only been able to speculate why. view more (2007-08-16)
Nuclear Medicine Imaging Allows Immediate Prediction of Advanced Breast Cancer Patients' Response to Hormonal Treatment Innovative use of somatostatin receptor scintigraphy (SRS), a nuclear medicine imaging technique looking at how the body functions at the molecular level, may provide near immediate selection of breast cancer patients for endocrine therapy and offers a new tool in fighting the disease. view more (2006-01-20)
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