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Olfactory nerve cells expressing same receptor display a varied set of reactions
n a mouse model, University of Pennsylvania School of Medicine researchers discovered that olfactory sensory neurons expressing the same receptor responded to a specific odor with an array of speeds and sensitivities.   view more (2006-02-03)

Tarantula venom and chili peppers target same pain sensor
Venom from a West Indian tarantula has been shown to cause pain by exciting the same nerve cells in mice that sense high temperatures and the hot, spicy ingredient in chili peppers.   view more (2006-11-09)

Potential new targets for antidepressant medications
The news about antidepressant medications over the past several years has been mixed. The bad news from large multicenter studies such as STAR*D is that current antidepressant medications are effective, but not as effective as one might hope. Thus, there is a significant need for new treatment... view more (2008-08-27)

Marijuana-like compounds suppress the immune response
A group of Japanese scientists has discovered that cannabinoids can cause some white blood cells to lose their ability to migrate to the sites of infection and inflammation.   view more (2006-04-27)

Bisphenol A linked to chemotherapy resistance
Exposure to bisphenol A (BPA) may reduce the effectiveness of chemotherapy treatments, say University of Cincinnati (UC) scientists.   view more (2008-10-09)

Caltech scientists engineer supersensitive receptor, gain better understanding of dopamine system
Genetically modifying a receptor found on the neurons that produce the neurotransmitter dopamine has given California Institute of Technology (Caltech) researchers a unique glimpse into the workings of the brain's dopamine system--as well as a new target for treating diseases that result from... view more (2008-10-15)

Food restriction increases dopamine receptor levels in obese rats
A brain-imaging study of genetically obese rats conducted at the U.S. Department of Energy's Brookhaven National Laboratory provides more evidence that dopamine - a brain chemical associated with reward, pleasure, movement, and motivation - plays a role in obesity.   view more (2007-10-25)

Drug developed at UC Davis may prevent breast cancer, treat post-menopausal vaginal atrophy
A tamoxifen-like drug developed by UC Davis and Finnish researchers, now in clinical testing as a treatment for vaginal atrophy, may also help to prevent breast cancer, two preliminary studies suggest.   view more (2005-11-03)

Treating osteoporosis calls for physician, dentist collaboration: ADA Journal
Physicians and dentists should collaborate to improve early detection and treatment of patients who have or may develop osteoporosis, say researchers in the cover story of the May issue of The Journal of the American Dental Association.   view more (2008-05-16)

Decrease in breast cancer rates related to reduction in use of hormone replacement therapy
The sharp decline in the rate of new breast cancer cases in 2003 may be related to a national decline in the use of hormone replacement therapy (HRT), according to a new report in the April 19, 2007, issue of the New England Journal of Medicine.   view more (2007-04-19)

Ashwell receptor reduces mortality during sepsis
In research that solves the longest-standing mystery in glycobiology - a field that studies complex sugar chains called glycans - researchers at the University of California, San Diego School of Medicine have discovered that a molecule in the liver of all animals, called the Ashwell receptor, is... view more (2008-05-19)

Study advances evidence for receptor's role in alcohol pleasure and problems
A genetic variant of a receptor in the brain's reward circuitry heightens the stimulating effects of early exposures to alcohol and increases alcohol consumption, according to a new study by researchers at the National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the National... view more (2007-03-07)

Oral contraceptives associated with reduced risk of multiple sclerosis
Over a three-year period, the risk of developing multiple sclerosis (MS) was reduced in women taking oral contraceptives, according to a study in the September issue of Archives of Neurology, one of the JAMA/Archives journals.   view more (2005-09-13)

Researchers look to the brain to explain gender differences in sleep apnea
The neural pathways between two areas of the brain that control the tongue - and their interactions with each other - may hold the key as to why men suffer sleep apnea much more than women.   view more (2006-04-04)

A double-barreled immune cell approach for neuroblastoma
Adding an artificial tumor-specific receptor to immune system cells called T-lymphocytes that target a particular virus extended and improved the cells' ability to fight a form of childhood cancer called neuroblastoma, said researchers form Baylor College of Medicine and Texas Children's Hospital... view more (2008-11-03)

Endosome-mediated signaling in plants
In a paper that will be published online in advance of its July 1st publication date, Drs. Niko Geldner, Joanne Chory and colleagues (The Salk Institute and HHMI) demonstrate that endosomes can function as signaling platforms in plants, as well as in animals.   view more (2007-06-19)

New mechanism for cardiac arrhythmia discovered
It has long been thought that virus infections can cause cardiac arrhythmia. But why has not been understood. Ulrike Lisewski, Dr. Yu Shi, Michael Radke and Professor Michael Gotthardt of the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch, Germany, have now discovered the... view more (2008-09-18)

Discovering New Regulators Of The Immune System
London, U.K. and South San Francisco, CA, 15th September 2003. In an attempt to find new regulators of the immune system, a team of researchers at Rigel Pharmaceuticals, Inc. have created a successful method for discovering molecules that are involved in signalling pathways. As published this week... view more (2003-09-12)

Glycoprotein hormone receptors
We have aspired at understanding and further dissecting the molecular mechanism of activation of the Glycoprotein hormone receptors (GpHr), members of the G protein coupled receptor (GPCR) superfamily.   view more (2006-01-17)

Researchers explore the antidepressant effects of ketamine
Drug treatments for depression can take many weeks for the beneficial effects to emerge. The excruciating and disabling nature of depression highlights the urgency of developing treatments that act more rapidly.   view more (2008-02-22)

Ethnic variations in hormone levels may cause differences in breast cancer risk
Researchers have known that a woman's natural hormone levels can affect her risk of developing breast cancer. A new study from the University of Southern California (USC) has found that the natural levels of estrogens in post-menopausal women varies by ethnicity and race, and may explain the... view more (2006-10-10)

Two Proteins May Be Survival Markers in Some Breast Cancers
New research suggests that the presence or absence of two proteins may be important markers for long-term survival in some breast-cancer patients.   view more (2007-11-14)

Drop in breast cancer incidence linked to hormone use, not mammograms
A recent decline in breast cancer incidence is unlikely to be caused by a decrease in mammography screening.   view more (2007-08-15)

Turning on hormone tap could aid osteoporosis fight
A potential new drug that 'opens the taps' for the release of useful hormones could stimulate new bone growth - and may eventually bring relief to osteoporosis sufferers.   view more (2008-07-16)

Pregnancy and lactation may affect maternal behavior and coping skills
In the October 2006 issue of the journal Endocrinology, a collaborative research study by scientists at Cummings School of Veterinary Medicine at Tufts University and the University of Otago Medical School in Dunedin, New Zealand, shows that pregnancy and lactation in rodents produce long-term... view more (2006-09-21)
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