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Long-term estrogen therapy linked to breast cancer risk
Long-term estrogen therapy may be related to a higher risk of breast cancer among postmenopausal women who have had a hysterectomy, according to an article in the May 8 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.   view more (2006-05-09)

Researchers say estrogen can kill breast cancer cells once fueled by the hormone
Fox Chase Cancer Center researchers say some breast cancer cells once fueled by estrogen can be killed by the same hormone.   view more (2005-12-07)

New biomarker predicts effectiveness of breast cancer drugs
University of Cincinnati (UC) researchers have identified a new way to predict when anti-estrogen drug therapies are inappropriate for patients with hormone-dependent breast cancer.   view more (2006-12-08)

Estrogen therapy helps or hurts the brain depending on reproductive status
Estrogen therapy may limit stroke damage if started close to, but not long after reproductive cycles are over, according to a new animal study. The results were presented Sunday, June 15, at The Endocrine Society's 90th Annual Meeting in San Francisco.   view more (2008-06-16)

Estrogen plus testosterone therapy may increase risk of breast cancer in postmenopausal women
Women who take a combination of estrogen and testosterone to treat the symptoms of menopause may have an increased risk of breast cancer.   view more (2006-07-25)

Estrogen withdrawal results in bone loss, research shows that the Estrogen Receptor has a fundamental role
Professor Lance Lanyon, Principal of The Royal Veterinary College, Karla Lee, Helen Jessop, Rosemary Suswillo, Gul Zaman from the Department of Basic Sciences at The Royal Veterinary College have shown in their research that the Estrogen Receptor has a fundamental role in bone cells by adjusting... view more (2003-07-25)

Fewer wrinkles and firmer skin linked to earlier use of estrogen therapy
Long-term hormone estrogen therapy used earlier in menopause is associated with fewer wrinkles and less skin rigidity in postmenopausal women, Yale School of Medicine researchers report in the August issue of Fertility and Sterility.   view more (2005-08-29)

Postmenopausal hormone therapy appears to increase risk of blood clots in veins
Estrogen therapy may increase the risk of venous thrombosis, the formation of blood clots in the veins, among postmenopausal women who have had their uterus removed.   view more (2006-04-11)

Estrogen-progestin menopausal hormone therapy and risk of lobular and tubular breast cancer
Estrogen-progestin menopausal hormone therapy is associated with a more than two-fold higher relative risk of developing lobular cancer or tubular cancer than of developing ductal cancer.   view more (2006-02-17)

Blood cholesterol levels predict risk of heart disease due to hormone therapy
A new analysis of a subgroup of participants in the Women's Health Initiative (WHI) hormone therapy clinical trials suggests that healthy, postmenopausal women whose blood cholesterol levels are normal or lower are not at increased, short-term risk for heart attack when taking hormone therapy.   view more (2008-05-27)

Estrogen therapy does not appear to protect postmenopausal women from heart disease
Estrogen therapy does not appear to reduce the risk of heart attack or coronary death in healthy postmenopausal women, although some data suggest a lower coronary heart disease risk in women aged 50 to 59 years.   view more (2006-02-14)

Early estrogen therapy to prevent heart disease focus of Yale study
Researchers at Yale School of Medicine and seven other national institutions are recruiting patients to participate in the Kronos Early Estrogen Prevention Study (KEEPS) to look at the effects of estrogen on heart disease prevention.   view more (2005-08-16)

Study of early estrogen's effect on heart disease similar to WHI findings
Researchers in The Department of Obstetrics, Gynecology & Reproductive Sciences at Yale have launched the Kronos Early Estrogen Prevention Study (KEEPS), which will further understanding of the possible beneficial effects on the heart and arteries and/or quality of life in recently menopausal... view more (2006-03-01)

Studies Examine Menopausal Hormone Therapy and Risk of Breast Cancer Recurrence
The doses of estrogen and progestogen used in menopausal hormone therapy may be related to the risk of breast cancer recurrence, according to a new study in the April 6 issue of the Journal of the National Cancer Institute. In 1997, two randomized trials, the Hormonal Replacement Therapy-Is It... view more (2005-04-06)

Estrogen curbs appetite in same way as the hormone leptin
Estrogen regulates the brain's energy metabolism in the same way as the hormone leptin, leading the way to a viable approach to tackling obesity in people resistant to leptin.   view more (2007-01-04)

Effects of progesterone on Alzheimer's disease
The first study on progesterone and Alzheimer's disease has found no clear preventive benefit for the widely prescribed hormone in an animal model.   view more (2007-11-28)

Researchers identify key gene that may be a marker of breast cancer metastasis
Researchers at Fox Chase Cancer Center have identified an important gene involved in the spread of breast cancer that has developed resistance to long-term estrogen deprivation.   view more (2007-04-19)

Cancer risk slightly higher for women in discontinued hormone treatment trial
A follow up study of participants in the Women's Health Initiative (WHI) clinical trial led by a University of North Carolina at Chapel Hill researcher has found that women who were taking the combined hormone therapy of estrogen plus progestin may have an increased risk of cancer since the... view more (2008-03-05)

Study uncovers significant functional differences of novel estrogen receptor
Because of these differences, this new estrogen receptor could become an important therapeutic target and may play a further signaling role in other estrogen target tissues, including uterus and prostate tissues.   view more (2006-06-09)

Unique estrogen receptor linked to metastatic breast cancer
Breast cancer awareness month may have passed, but researchers remain focused on the disease with a new study showing that a unique estrogen receptor found in breast cancer tumors is a predictor of tumor size and metastases.   view more (2006-11-01)

Low estrogen levels in men linked to increased risk for hip fracture
A new study has found that men with low estrogen levels have an increased risk for future hip fracture, and those with both low estrogen and low testosterone levels have the greatest risk.   view more (2006-05-01)

Soy phytoestrogens may block estrogen effects
Research in monkeys suggests that the natural plant estrogens found in soy do not increase markers of breast cancer risk in postmenopausal women.   view more (2006-01-16)

New predictive tool can help determine treatment of breast cancer patients
A new predictive measurement, called a PEPI score, could bring good news to many women diagnosed with early stage breast cancer - a low PEPI (preoperative endocrine prognostic index) score could show that they have little risk of relapse and can safely avoid chemotherapy after surgery.    view more (2008-09-24)

Effect of hormone therapy on risk of heart disease may vary by age and years since menopause
Secondary analyses of findings from the Womenˇ¦s Health Initiative (WHI) suggest that women who begin hormone therapy within 10 years of menopause may have less risk of coronary heart disease (CHD) due to hormone therapy than women farther from menopause.   view more (2007-04-04)

Study finds it pays to be heart smart if considering hormone therapy
A research study has found that a simple blood test may indicate whether post-menopausal hormone therapies present an elevated risk of a heart attack.   view more (2008-05-22)

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