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Anti-wrinkle compound causes pathological reaction in skin cells
Researchers from Université Laval's Faculty of Medicine have discovered that a compound commonly used in many antiwrinkle products causes a pathological reaction in skin cells.   view more (2007-04-12)

Genetic on-off switches pinpointed in human genome
In another step to decipher information in the human genome, scientists have discovered the location and sequence of over 10,000 DNA regions that function as genetic on-off switches, or "promoters" in human fibroblasts.    view more (2005-07-01)

Study helps explain origins of cardiac fibrosis in patients with heart disease
A report led by researchers at Beth Israel Deaconess Medical Center (BIDMC) helps explain the origins of cardiac fibrosis, a stiffening of the heart muscle that leads to a variety of cardiac diseases, most notably heart failure.   view more (2007-07-30)

Scientists identify embryonic stem cells by appearance alone
Some scientific results are hard to spot, especially in genetic research. Often scientists are unable to physically see if the gene they inserted into a cell has produced the desired trait.   view more (2007-08-28)

Molecular pathway appears crucial in development of pulmonary fibrosis
A study led by Massachusetts General Hospital (MGH) researchers may have found a key mechanism underlying idiopathic pulmonary fibrosis (IPF), a usually fatal lung disease for which transplantation is the only successful treatment.   view more (2007-12-13)

Green tea compound suppresses factors causing cartilage, bone destruction in arthritis
In rheumatoid arthritis, a person's own immune system attacks the joints by activating the synovial tissue that lines the body's movable joints, causing inflammation, swelling, pain and eventually erosion of the bone and cartilage and deformation of the joint.   view more (2007-04-30)

Clever cells could banish gum disease, stretch marks and baldness
A simple treatment involving skin cell injections may be used to treat a number of common complaints including stretch marks, gum disease and baldness, reports Chemistry & Industry magazine.   view more (2005-04-26)

Green tea compound may be a therapy for people with rheumatoid arthritis
A new study from the University of Michigan Health System suggests that a compound in green tea may provide therapeutic benefits to people with rheumatoid arthritis.   view more (2007-04-30)

Why passive smoking hinders healing
Being exposed to high levels of 'second-hand' smoke can reduce the speed at which wounds heal, leading to a lack of healing or greater levels of scarring. A study published in the journal BMC Cell Biology this week may begin to explain why: when cells are exposed to smoke, their ability to migrate... view more (2004-04-01)

Scientists identify novel way to prevent cardiac fibrosis
In a study that points to a new strategy for preventing or possibly reversing fibrosis - the scarring that can lead to organ and tissue damage - researchers at the University of California, San Diego School of Medicine have determined that a molecule called Epac (Exchange protein activated by... view more (2008-04-23)

Deakin University research finds rogue cells that could cause spread of breast cancer
Stephanie Lebret completed the study for her PhD at Deakin's Centre for Cellular and Molecular Biology under the supervision of Associate Professor Leigh Ackland.   view more (2007-06-14)

A twist of fate -- Reprogrammed fibroblasts resemble embryonic stem cells
Stem cell biology takes another exciting leap forward as scientists report that normal tissue cells can be reprogrammed to exhibit many of the properties that are characteristic of embryonic stem cells, including the ability to give rise to multiple cell types and contribute to the germline.   view more (2007-06-07)

Tissue Engineering Restores Cornea
The Moscow scientists have conducted clinical trials of a new method for treatment of deep burns of cornea. Their effort has been supported by the Russian Foundation for Basic Research.   view more (2005-04-05)

UCLA researchers reprogram normal tissue cells into embryonic stem cells
Researchers at the Institute for Stem Cell Biology and Medicine at UCLA were able to take normal tissue cells and reprogram them into cells with the same unlimited properties as embryonic stem cells, the cells that are able to give rise to every cell type found in the body.   view more (2007-06-07)

Good news for a fast-wrinkling generation: Some anti-aging methods work
Fine wrinkles, deeper creases, saggy areas around the mouth and neck - the sights in the mirror that make baby boomers wince - are not inevitable. They result from a structural breakdown inside the skin that some existing treatments effectively counteract by stimulating the growth of new, youthful... view more (2008-05-29)

Cancer support cells may evolve, fuel tumor growth, study shows
University of North Carolina at Chapel Hill scientists have demonstrated in a living organism that cancers may cause surrounding supportive cells to evolve and ultimately promote cancer growth.   view more (2005-12-19)

Does natural selection drive the evolution of cancer?
The dynamics of evolution are fully in play within the environment of a tumor, just as they are in forests and meadows, oceans and streams. This is the view of researchers in an emerging cross-disciplinary field that brings the thinking of ecologists and evolutionary biologists to bear on cancer... view more (2006-11-20)

Pregnancy research leads to progress on premature delivery
The University of Rochester has filed a patent on several ideas to help prevent early labor and the premature delivery of low-birth-weight babies.   view more (2006-03-23)

Signaling for cartilage
Skeletal progenitor cells differentiate into cartilage cells when one master gene actually suppresses the action of another, said Baylor College of Medicine researchers in a report that appears online in the journal Proceedings of the National Academy of Sciences.   view more (2006-11-28)

Scientists unlock mystery of embryonic stem cell signaling pathway
A newly discovered small molecule called IQ-1 plays a key role in preventing embryonic stem cells from differentiating into one or more specific cell types, allowing them to instead continue growing and dividing indefinitely, according to research performed by a team of scientists who have recently... view more (2007-03-20)

New source of heart stem cells discovered
Researchers at Children's Hospital Boston are continuing to document the heart's earliest origins. Now, they have pinpointed a new, previously unrecognized group of stem cells that give rise to cardiomyocytes, or heart muscle cells.   view more (2008-06-23)

First different black/white mechanism in pulmonary fibrosis/scleroderma identified
Of the more than 40,000 persons who die each year in the U.S. from pulmonary fibrosis, the mortality rate among African-Americans is twice as high Caucasians.   view more (2006-04-05)

Brown Cancer Biologists Identify Major Player in Cell Growth
When cells go about the business of dividing, they can get sidelined. Maybe there aren't enough nutrients. Maybe there aren't the right signals to resume multiplying. Either way, cells go quiet.   view more (2007-02-07)

Scientists develope a new model of artificial canine skin
Researchers at UNIVET, a spin-off of the Universitat Autònoma de Barcelona, in cooperation with the animal nutrition company Affinity Petcare, have developed an artificial cellular model which faithfully reproduces the characteristics of dog's skin and which will allow, therefore, the... view more (2007-05-11)

Wound Healing - Discovery Of A New Therapeutic Strategy Against Hypertrophic Scarring
Wound healing appears generally a banal event, but in a certain proportion of cases it evolves inappropriately in hypertrophic scars resulting in skin and organ deformations. This is due to an excess of wound contraction, a phenomenon that generally helps to close the wound. Hypertrophic scarring... view more (2002-05-13)
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