Fibrotic Diseases Current Events | Fibrotic Diseases News
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Rice breakthrough could prevent multiple fibrotic diseases
A scientific breakthrough at Rice University could lead to the first treatment that prevents the build-up of deadly scar tissue in a broad class of diseases that account for an estimated 45 percent of U.S. deaths each year. view more (2007-01-19)
Surgical treatment a rare complication of duodenal diverticulum
Most of the duodenal diverticula are diagnosed incidentally and asymptomatic, 12% to 27 % at endoscopy. Only 5% to 10% of patients with duodenal diverticula suffer from clinical symptoms. view more (2009-08-26)
Scientists identify novel way to prevent cardiac fibrosis
In a study that points to a new strategy for preventing or possibly reversing fibrosis - the scarring that can lead to organ and tissue damage - researchers at the University of California, San Diego School of Medicine have determined that a molecule called Epac (Exchange protein activated by cAMP1), plays a key role in integrating the body's pro-... view more... (2008-04-23)
IL-21 receptor plays an essential role in the Th2 immune response
During the immune response cells known as Th2 cells express a variety of cytokines (e.g. interleukin-4, -5, and -13), many of which stimulate B cells to proliferate and produce antibodies. view more (2006-06-16)
A potential therapeutic agent for hepatic fibrosis
Accumulating evidence suggests that connective tissue growth factor (CCN2) plays a central role in fibrotic conditions in many organ systems. view more (2009-08-26)
First different black/white mechanism in pulmonary fibrosis/scleroderma identified
Of the more than 40,000 persons who die each year in the U.S. from pulmonary fibrosis, the mortality rate among African-Americans is twice as high Caucasians. view more (2006-04-05)
U-M scientists target key cells and signals that trigger pulmonary fibrosis
Scientists at the University of Michigan Medical School have identified biochemical signals that attract pathogenic cells to damaged lung tissue - one of the first steps in a chain of events leading to a lethal disease called idiopathic pulmonary fibrosis or IPF. view more (2006-05-24)
To protect against liver disease, body puts cells 'under arrest'
A stable form of cell-cycle arrest known to offer potent protection against cancer also limits liver fibrosis, a condition characterized by an excess of fibrous tissue, according to a new report in the August 22nd Cell, a Cell Press publication. view more (2008-08-22)
Protein may be strongest indicator of rare lung disease, study shows
Researchers at the University of Cincinnati (UC) have discovered a protein in the lungs that can help in determining progression of the rare lung disease Idiopathic Pulmonary Fibrosis (IPF). view more (2009-06-04)
Growth factor TGF-B helps maintain health of retinal blood vessels
Scientists at Schepens Eye Research Institute have found that the growth factor known as TGF-β is essential to the health of blood vessels in the retina and that blocking it can cause retinal dysfunction. view more (2009-04-08)
Senescence in liver cells is found by CSHL scientists to help limit acute tissue damage
Although post-reproductive life in humans is often associated with decline and a loss of powers, an analogous state in certain cells -- called senescence -- is proving to be one of ironic potency. Scientists at Cold Spring Harbor Laboratory (CSHL) today reported that a particular class of senescent liver cells orchestrates a sequence of events in... view more... (2008-08-22)
p90RSK: A new therapeutic target for liver fibrosis?
Cirrhosis is a world wide, bad prognosis liver disease and characterized by excessive collagen deposition and liver function damage. view more (2009-05-13)
U of M study shows why treatment isn't effective for HIV
University of Minnesota researchers have answered a key question as to why antiretroviral therapy isn't effective in restoring immunity in HIV-infected patients. view more (2008-08-06)
Liver fibrosis will be treated by a potential target
The outcome of hepatitis is either self recovery or its development into liver fibrosis or, further, liver cirrhosis. Liver fibrosis is the early pathological process of cirrhosis, which is considered a reversible, wound-healing response. Since no ideal drug is available for its therapy, liver fibrosis is currently considered to be a major... view more... (2007-10-17)
Taking the wrinkles out of motoneuronal disease
A winner of UniQuest's 2006 Trailblazer innovation competition, Dr Frederic Meunier, is developing a treatment for motoneuronal diseases based on modifying botox —the popular anti-wrinkle treatment. view more (2006-07-06)
Rare Lung Disease Cells Indicate Higher Death Risk
Large numbers of certain cells in the lungs of patients diagnosed with idiopathic pulmonary fibrosis may increase their chance of death, UC researchers have discovered. view more (2008-01-17)
Parasitic tropical diseases in the Americas, a legacy of slavery, can be eliminated
Although it has been speculated for more than a century that the slave trade was responsible for bringing many tropical diseases to the Americas, only recently has convincing evidence shown that lymphatic filariasis (elephantiasis), schistosomiasis, and onchocerciasis (river blindness) originated in this way. view more (2007-11-07)
Engineered molecule amplifies body's immune response
By altering a molecule called Stat1, which is involved in cellular immune signaling, scientists have succeeded in making the molecule more responsive and thus more efficient. view more (2005-09-29)
Molecular pathway appears crucial in development of pulmonary fibrosis
A study led by Massachusetts General Hospital (MGH) researchers may have found a key mechanism underlying idiopathic pulmonary fibrosis (IPF), a usually fatal lung disease for which transplantation is the only successful treatment. view more (2007-12-13)
Chronic diseases linked to falls in elderly women
Elderly women with chronic diseases, such as arthritis and depression, are at higher risk of falling, finds a study in this week's BMJ. In fact, chronic diseases may account for 30% of falls in this group. Researchers at the University of Bristol surveyed 4,050 women aged 60-79 years about whether they had had a fall in the previous 12 months, how... view more... (2003-09-24)
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