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Rapid movements of living biomolecules visualised
Dutch researcher Chris Molenaar has made the rapid movements of proteins, DNA and RNA molecules visible in living cells. With this technique researchers can study the dynamics of biomolecules in their natural environment. Molenaar developed a method which makes it possible to follow the movements... view more (2003-06-24)

Biomedical research profits from the exploration of the deep sea
A study published in the scientific journal PLoS ONE highlights how the exploration of the ocean depths can benefit humankind.   view more (2008-11-20)

Biomedical research profits from the exploration of the deep sea
A study published in the scientific journal PLoS ONE highlights how the exploration of the ocean depths can benefit humankind.   view more (2008-11-20)

Structural basis for photoswitching in fluorescent proteins brought into focus
University of Oregon scientists have identified molecular features that determine the light-emitting ability green fluorescent proteins, and by strategically inserting a single oxygen atom they were able to keep the lights turned off for up to 65 hours.   view more (2007-04-11)

Making proteins glow blue
In the beginning, there was protein. 19th-century scientists at least believed that this group of organic compounds were based on some kind of primeval matter. Therefore they named them "proteins" - derived from the Greek word "protos" (the first). It is meanwhile known that the... view more (2003-09-18)

New technology illuminates protein interactions in living cells
While fluorescence has long been used to tag biological molecules, a new technology developed at Yale allows researchers to use tiny fluorescent probes to rapidly detect and identify protein interactions within living cells while avoiding the biological disruption of existing methods, according to... view more (2007-11-12)

The UAB heads a European research project on proteases and pathological processes
A research group of the UAB Institute of Biotechnology and Biomedicine and the UAB Department of Biochemistry and Molecular Biology, directed by Francesc Xavier Avilés, is the coordinator of a European project aimed at studying proteases with fluorescent molecules that allow their monitoring... view more (2007-07-18)

Yale researchers make cell biology quantitative
Yale researchers have reported a method to count the absolute number of individual protein molecules inside a living cell, and to measure accurately where they are located, two basic hurdles for studying biology quantitatively.   view more (2005-10-20)

Topical Papers in Biochemical Journal - Selective determination of mitochandrial chelatable iron in viable cells with a new fluorescent sensor
This paper by Petrat and colleagues marks an important advance in our understanding of the regulation of iron in the human body. Real-time changes in the concentration of the ionized form of iron (Fe2+) can now be monitored within the mitochondria of living cells for the first time, thanks to the... view more (2002-02-08)

Magnet Lab researchers make observing cell functions easier
Now that the genome (DNA) of humans and many other organisms have been sequenced, biologists are turning their attention to discovering how the many thousands of structural and control genes -- the "worker bees" of living cells that can turn genes on and off -- function.   view more (2008-05-09)

Scripps Scientists Discover Fluorescence in Key Marine Creature
Fluorescent proteins found in nature have been employed in a variety of scientific research purposes, from markers for tracing molecules in biomedicine to probes for testing environmental quality. Until now, such proteins have been identified mostly in jellyfish and corals, leading to the belief... view more (2007-10-31)

New protein tag enhances view within living cells
The view into the inner world of living cells just got a little brighter and more colorful. A powerful new research tool, when used with other labeling technologies, allows simultaneous visualization of two or more different proteins as well as the ability to distinguish young and old copies of a... view more (2008-02-25)

Fluorescence microscopy reveals why some antifreeze proteins inhibit ice growth better than others
Antifreeze or "ice structuring" proteins - found in some fish, insects, plants, fungi and bacteria - attach to the surface of ice crystals to inhibit their growth and keep the host organism from freezing to death.   view more (2007-03-07)

Sea Coral's Trick Helps Scientists Tag Proteins
The glow emitted by a variety of sea coral helped Russian scientists harness the protein that generates the light to create a tiny fluorescent tag that responds to visible light.   view more (2006-03-20)

Boston University scientists develop new application to characterize structure of DNA molecules
A team of researchers from Boston University has developed a new application to enable more precise measurement of the location of a fluorescent label in a DNA layer.   view more (2006-03-01)

DNA gets new twist: Carnegie Mellon scientists develop unique 'DNA nanotags'
Carnegie Mellon University scientists have married bright fluorescent dye molecules with DNA nanostructure templates to make nanosized fluorescent labels that hold considerable promise for studying fundamental chemical and biochemical reactions in single molecules or cells.   view more (2007-01-29)

Revolutionary nanotechnology illuminates brain cells at work
Until now it has been impossible to accurately measure the levels of important chemicals in living brain cells in real time and at the level of a single cell. Scientists at the Carnegie Institution's Department of Plant Biology and Stanford University are the first to overcome this obstacle by... view more (2005-05-30)

MIT particles pave way for new bedside diagnostics
MIT researchers have created an inexpensive method to screen for millions of different biomolecules (DNA, proteins, etc.) in a single sample-a technology that could make possible the development of low-cost clinical bedside diagnostics.   view more (2007-03-09)

Clemson scientists shed light on molecules in living cells
Clemson University chemists have developed a method to dramatically improve the longevity of fluorescent nanoparticles that may someday help researchers track the motion of a single molecule as it travels through a living cell.   view more (2007-08-21)

Are we trading energy conservation for toxic air emissions?
A team of Yale scientists has found that certain countries and some U.S. states stand to benefit from the use of compact fluorescent lighting more than others in the fight against global warming. Some places may even produce more mercury emissions by switching from incandescent light bulbs to... view more (2008-10-01)

Sticky dust fingers the culprits
EMBARGOED UNTIL WEDNESDAY 5 NOVEMBER 19:00 HRS GMT NANOPARTICLES could give police the clearest fingerprints yet. Officers search for prints by dusting a crime scene with fluorescent powder. This sticks to the oily residue left by the fingertip, showing up the whorls and ridges. But sometimes the... view more (2003-11-05)

Counting semi-viable bacteria in cheese
The Wageningen researcher Christine Bunthof has developed a direct method for counting bacteria in dairy products. The method not only distinguishes viable and non-viable bacteria but also semi-viable bacteria. These are too weak to divide, but still exhibit activity. The semi-viable bacteria play... view more (2002-05-23)

Sugar metabolism tracked in living plant tissues, in real time
Scientists at Carnegie's Department of Plant Biology have made the first real-time observations of sugars in the cells of intact and living plant tissues.   view more (2006-09-01)

Candy-coating keeps proteins sweet
Sugar-frosting isn't just for livening up boring bran flakes; it can also preserve important therapeutic proteins. Researchers at the National Institute of Standards and Technology (NIST) have developed a fast, inexpensive and effective method for evaluating the sugars pharmaceutical companies use... view more (2008-08-20)

UF, Columbia scientists closer to new cancer detection method
University of Florida researchers say they are a step closer to a technique to easily detect a wide variety of cancers before symptoms become apparent.   view more (2005-11-30)
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