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Folic acid deficit increased risk of miscarriage in early pregnancy
Low levels of folic acid in plasma have been associated with an increased risk of miscarriage in a study published in Journal of the American Medical Association lately. On the other hand, no connection was found between high levels of folic acid and increased risk of miscarriage. In the US folic acid is added to flour to prevent pregnant women... view more... (2002-10-22)

No Increased Risk of Miscarriage From Folic Acid Supplements (p 796)
Women who consume folic acid supplements around the time of conception are not at an increased risk of miscarriage, conclude authors of a population-based study published in this weke’s issue of THE LANCET. Although it is well known that folic acid supplements can reduce the risk of infant neural-tube defects (NTDs), its effects on other... view more... (2001-09-05)

Food Fortification With Vitamin B12 In Addition To Folic Acid Could Reduce Risk Of Cardiovascular Disease (p 227)
Authors of a research letter in this week's issue of THE LANCET conclude that vitamin B12 in addition to folic acid should be used to fortify food to lower concentrations of the blood protein homocysteine, thereby potentially reducing the risk of cardiovascular disease. Mandatory fortification of grain foods with folic acid has been in place in... view more... (2002-01-17)

Multivitamins with 0.4 - 0.8 mg of folic acid are best in birth defect prevention
Periconceptional use of folic acid supplements is effective for the primary prevention of neural-tube defects and is recommended by reproductive health researchers. Recent research in this area, however, centres on two main debated questions. The first one is whether the use of folic acid alone or folic acid-containing multivitamins is better. The... view more... (2004-05-27)

Folic Acid Supplements Not Linked To Multiple Births (p 380)
Results of a Chinese population-based study in this week's issue of THE LANCET provide strong evidence that women who take folic acid supplements during pregnancy do not have an increased likelihood of having a multiple birth. Folic acid supplements are recommended for women of childbearing age to prevent neural tube defects-such as spina bifida... view more... (2003-01-29)

Only one-third of women take vitamin to help prevent serious birth defects, survey finds
Only one-third of childbearing age women are taking a multivitamin containing the B vitamin folic acid daily to prevent serious birth defects of the brain and spine in their future babies, according to a decade of March of Dimes surveys.   view more (2005-09-30)

Folic acid cuts risk of cleft lip
Taking folic acid supplements in early pregnancy seems to substantially reduce the risk of cleft lip.   view more (2007-01-29)

Governments committing "public health malpractice" over flour fortification
The failure of European governments, including the United Kingdom, to fortify flour with folic acid has allowed a continuing epidemic of preventable human illness, according to an editorial in this week's BMJ. Fortification could save as many lives as are lost each year in vehicle crashes, writes Professor Godfrey Oakley of Emory University in the... view more... (2002-06-05)

Dutch diet contains too little folic acid
The average Dutch person consumes about 85% of the recommended daily intake of folic acid. Furthermore, it is estimated that our bodies fail to absorb no less than one quarter of the folic acid in food. These findings were made by Alida Melse-Boonstra during her doctoral research, which she carried out at the Wageningen Centre for Food Sciences... view more... (2003-09-05)

Folic acid could prevent heart disease
Folic acid could dramatically reduce the risk of heart disease, deep vein thrombosis, and stroke if levels of homocysteine (an amino acid) were reduced, according to researchers in this week’s BMJ.   view more (2002-11-20)

Are certain congenital birth defects and heart disease linked?
The study implicates homocysteine, a chemical by-product of human metabolism. Homocysteine is particularly important for cell growth and is regulated by enzymes, the activities of which are partly genetically determined, and partly affected by diet, including the levels of vitamins B6, B12, and folic acid in the blood.   view more (1999-11-15)

Scientists question folic acid fortification
Scientists at the Institute of Food Research have highlighted possible consequences of fortifying flour with folic acid due to new evidence of how it is absorbed by the body.   view more (2007-11-05)

A safe folic acid boost from flour
Public consumption of folic acid from fortified flour at current mandated US levels (100micro-gram/day) and at double this amount is probably safe, at average intakes, according to an article published today in the open access journal BMC Public Health.   view more (2007-03-22)

Food Supplementation With Folic Acid Could Substantially Reduce Neural-Tube Defects (p 2047)
A public-health initiative to enrich cereal grain foods in Canada with folic acid has halved the prevalence of neural-tube defects among both unborn and newborn children, report authors of a research letter in this week's issue of THE LANCET. Folic acid tablet supplementation around the time of conception is known to dramatically reduce the risk... view more... (2002-12-18)

Folic acid to prevent congenital heart defects
The Canadian policy of fortifying grain products with folic acid has already proved to be effective in preventing neural tube defects.   view more (2009-05-15)

Immigrant women may be at higher risk of having a baby with a birth defect
Immigrant women are less likely to use folic acid supplements before pregnancy to prevent spina bifida, particularly those who recently immigrated to the country, according to a new study led by a St. Michael's Hospital physician in collaboration with Statistics Canada, Health Canada and the University of Toronto.   view more (2009-04-17)

High doses of folic acid may help to prevent stomach cancer
High doses of folic acid may help to prevent digestive tract cancers, suggests animal research reported in Gut.   view more (2001-12-17)

Concerns raised over policy to add folic acid to flour
A UK Department of Health committee has now recommended universal fortification of flour with folic acid to reduce the level of neural tube defects. Yet researchers in this week's BMJ warn that we need to be cautious before introducing such a policy. Although the benefits of supplementation are clear, the possible harms of such a policy are not,... view more... (2001-11-20)

News brief: Effects of aspirin and folic acid on inflammation markers for colorectal adenomas
Unexpectedly, inflammation markers do not appear to be involved with the chemopreventative effect of aspirin on colorectal adenomas, according to a brief communication published online October 12 in the Journal of the National Cancer Institute.   view more (2009-10-13)

Fortifying food with folic acid benefits babies
Adding folic acid to food can dramatically reduce the incidence of spina bifida and other birth defects. A study, published today in BMC Pregnancy and Childbirth, shows that the proportion of babies born with neural tube defects in the province of Newfoundland and Labrador dropped by 78% after the Canadian Government directed that folic acid must... view more... (2004-09-23)
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