Forebrain Malformation Current Events | Forebrain Malformation News
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Barrow researchers identify new brain receptor, possible target for Alzheimer's treatment
Barrow Neurological Institute researchers have identified a novel receptor in the brain that is extremely sensitive to beta-amyloid peptide (AB) and may play a key role in early stages of Alzheimer's disease. view more (2009-07-17)
Poor diabetes control linked to pregnancy complications
Women with poorly controlled diabetes during early pregnancy run an increased risk of their baby being malformed, finds a study in this week’s BMJ. view more (2002-11-27)
Taking back-to-school to heart
With a new environment, new friends and new activities, the first day of school is a big step in the lives of young school-age children and one that requires all their cognitive, motor and social-emotional skills. view more (2008-09-16)
Study rules out inbreeding as cause of amphibian deformities
Although research has linked inbreeding with elevated rates of deformity in a wide variety of animals, a new study finds it plays no part in the high incidence of malformation among salamanders. view more (2008-10-29)
Causative gene for human "lobster claw" syndrome identified
A new study using mouse "knockouts" shows that genes that control limb formation in insects have similar functions in mammals. Split hand/foot malformation (SHFM) or ectrodactyly (the "lobster claw" anomaly), is a severe congenital malformation syndrome characterised by a profound median cleft of the hands and/or feet, typically associated with... view more... (2002-05-21)
Fears over ICSI largely groundless say fertility experts
Embargoed: 00.01 BST Wednesday 29 March 2000 Fears over ICSI largely groundless say fertility experts Most abnormalities in ICSI babies linked to multiple or premature births Fears that the controversial fertility treatment known as ICSI could cause a high level of abnormalities among babies are largely unfounded, according to major new research... view more... (2000-03-23)
QBI neuroscientists make Alzheimer's disease advance
Queensland Brain Institute (QBI) neuroscientists at UQ have discovered a new way to reduce neuronal loss in the brain of a person with Alzheimer's disease. view more (2008-06-10)
Regulatory pathway in brain development possible basis for malformations
Researchers at the University of California, San Diego (UCSD) School of Medicine have identified a genetic regulator of brain development that sheds new light on how immature neural cells choose between proliferation and differentiation. view more (2006-12-05)
New insight into most common forebrain malformation
St. Jude Children's Research Hospital scientists have identified one of the molecular mechanisms underlying the genetic brain malformation called holoprosencephaly (HPE). The findings not only yield insights into the most common developmental malformation of the anterior brain and face in newborns, but also help in understanding the intricate... view more... (2008-08-12)
EURYI project to understand how the brain wires during embryogenesis
One of the great questions of neurobiology, how the brain is built up during embryonic development, could be resolved by a young French scientist in an award winning project organised by the European Science Foundation (ESF) and the European Heads of Research Councils (EuroHORCS). view more (2007-09-24)
Unlikely genetic suspect implicated in common brain defect
A genetic search that wound its way from patients to mouse models and back to patients has uncovered an unlikely gene critically involved in a common birth defect which causes mental retardation, motor delays and sometimes autism, providing a new mechanism and potentially improving treatment for the disorder. view more (2009-08-10)
Epilepsy drugs in pregnancy can triple risk of major malformation or developmental delay in children born
Epilepsy drugs given to women during pregnancy can treble the risk of congenital malformation or developmental delay in their children, finds research in the Journal of Medical Genetics. view more (2002-04-09)
Bird brains suggest how vocal learning evolved
Though they perch far apart on the avian family tree, birds with the ability to learn songs use similar brain structures to sing their tunes. Neurobiologists at Duke University Medical Center now have an explanation for this puzzling likeness. view more (2008-03-12)
Key gene controlling eye lens development identified
Investigators at St. Jude Children's Research Hospital have discovered in mouse models that a gene called Six3 is one of the earliest critical regulators controlling lens development in the eye of the mammalian embryo. view more (2006-10-27)
Birth defect gene identified
Birth defects of the face and skull are relatively common in humans, striking one in 500 to 1,000 babies. Defects can include cleft lip or palate, congenitally missing teeth and severe malformations of the skull. view more (2005-12-23)
ICSI or IVF: Babies born from frozen embryos do just as well
Analysis of the longest running ICSI programme in the United States has found reassuring evidence that babies born from frozen embryos fertilised via ICSI (intracytoplasmic sperm injection) do just as well as those born from frozen embryos fertilised via standard IVF treatment. view more (2009-06-30)
Lack of sleep activates body's defence mechanisms
A lack of sleep is considered a threat situation, which activates the body's defence mechanisms. This is the same type of response that protects the body against viruses and bacteria as well as in stress situations. view more (2005-03-16)
Concerns raised over policy to add folic acid to flour
A UK Department of Health committee has now recommended universal fortification of flour with folic acid to reduce the level of neural tube defects. Yet researchers in this week's BMJ warn that we need to be cautious before introducing such a policy. Although the benefits of supplementation are clear, the possible harms of such a policy are not,... view more... (2001-11-20)
Spray to Stop Scarring in Development
A spray that halves the healing time of burns and wounds is being designed for immediate use. Marina Murphy explains how the spray could be the difference between having a disfiguring scar or not in Chemistry & Industry magazine. view more (2004-10-28)
USC researchers identify alternate pathway that leads to palate development
Researchers at the University Of Southern California School Of Dentistry have uncovered another clue behind the causes of cleft palate and the process that leads to palate formation. view more (2008-08-11)
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