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Lactic acid not athlete's poison, but an energy source-if you know how to use it
In the lore of marathoners and extreme athletes, lactic acid is poison, a waste product that builds up in the muscles and leads to muscle fatigue, reduced performance and pain. view more (2006-04-20)
CSHL scientists discover new details of a gene-regulatory network governing metabolism
Metabolism is a central feature of life - a myriad of biochemical processes that, together, enable organisms to nourish and sustain themselves. Scientists at Cold Spring Harbor Laboratory (CSHL) are in the forefront of efforts to demonstrate how the regulation of genes governs fundamental life processes, including metabolism. view more (2008-02-25)
Stress causes parodontis
Under stress, major proteins get actively destroyed in the parodentium. According to biologists' data, chronical stress inhibits the osseous tissue maturing process and intensifies decomposition of collagen protein and proteoglycans with the animals non-resistant to stress. Stress intensifies hydrolysis of proteins, which make the basis of the... view more... (2003-09-26)
Drug mimics low-cal diet to ward off weight gain, boost running endurance
A drug designed to specifically hit a protein linked to the life-extending benefits of a meager diet can essentially trick the body into believing food is scarce even when it isn't, suggests a new report in the November Cell Metabolism. view more (2008-11-05)
Smoking reduces alcohol's effects, likely encouraging more drinking
It's no mystery that many drinkers smoke, and many smokers drink. What is novel is a recent finding among rodents that nicotine can reduce blood alcohol concentrations (BACs) at dosage levels that could be achieved by human smokers. This may lead to more drinking. view more (2006-07-25)
Computational model simulates AZT metabolism in mitochondria
Researchers at the Virginia Bioinformatics Institute (VBI) at Virginia Tech have developed a computational model that allows scientists to better understand the metabolism and toxicity of the HIV/AIDS drug zidovudine (azidothymidine, AZT). view more (2006-07-25)
New findings shed light to the mechanisms of Parkinson's disease
The findings of Finnish scientists with their multinational collaborators shed light to the mechanisms of Parkinson's disease and early menopause. view more (2004-09-07)
Jefferson Scientists Uncover Lethal Gene Mutation Key to Blocking Cholesterol Processing
When Jefferson Medical College researcher Shiu-Ying Ho, Ph.D., and her colleagues first created a mutation that limited the absorption of lipids and cholesterol into the bloodstream in zebrafish, the possibilities seemed endless. view more (2006-04-20)
Blood-flow metabolism mismatch predicts pancreatic tumor aggressiveness
Researchers from Turku, Finland, have identified a blood-flow glucose consumption mismatch that predicted pancreatic tumor aggressiveness, according to results of a study published in Clinical Cancer Research, a journal of the American Association for Cancer Research. view more (2009-08-26)
Ume'å scientist honored for article on stress hormone and diabetes
Eva Rask at the Department of Public Health and Clinical Medicine, Ume'å University, Sweden, has been awarded a scholarship from the Swedish Association for Diabetology for the year's best scientific article in Swedish diabetes research in 2001. The article, published in The Journal of Clinical Endocrinology and Metabolism, describes how the... view more... (2002-04-08)
Hydrogen Peroxide's Link to Living Cells
If a circadian rhythm is like an orchestra - the united expression of the rhythms of millions of cells - a common chemical may serve as the conductor, or at least as the baton. view more (2009-11-04)
Eating and weight gain not necessarily linked, study shows
A new study shows that increased eating does not necessarily lead to increased fat. The finding in the much-studied roundworm opens the possibility of identifying new targets for drugs to control weight, the researchers say. view more (2008-06-04)
Key site in iron metabolism aids in diagnosing anemia of chronic disease
University of Utah School of Medicine researchers have developed a new tool that facilitates diagnosis of anemia related to chronic illness, as well as diseases of iron overload. The results of a study detailing the new tool are published in the August 2008 issue of the journal Cell Metabolism, a publication of Cell Press. view more (2008-08-06)
Cancer metabolism discovery uncovers new role of IDH1 gene mutation in brain cancer
Agios Pharmaceuticals today announced that its scientists have established, for the first time, that the mutated IDH1 gene has a novel enzyme activity consistent with a cancer-causing gene, or oncogene. view more (2009-11-23)
Changes to DNA linked to diabetes
Genes that regulate the energy consumption of cells have a different structure and expression in type II diabetics than they do in healthy people, according to a new study from the Swedish medical university Karolinska Institutet published in Cell Metabolism. view more (2009-09-02)
Gene discovery opens door to tackling disease
Western Australian researchers have discovered a new gene that could lead to breakthroughs in breast and prostate cancer, as well as diabetes. view more (2006-06-09)
How appetite-stimulating brain cells work overtime during fasting
During periods of fasting, brain cells responsible for stimulating the appetite make sure that you stay hungry. Now, a new study of mice reported in the January issue of the journal Cell Metabolism, published by Cell Press, reveals the complex series of molecular events that keep those neurons active. view more (2007-01-03)
Drug prescribed for migraines and seizures increases risk of kidney stones
Topiramate (Topamax), a drug commonly prescribed to treat seizures and migraine headaches, can increase the propensity of calcium phosphate kidney stones, researchers at UT Southwestern Medical Center have found. view more (2006-11-01)
Activating protein enhances average lifespan, limits age-related disease in mice
Metabolism researchers at Washington University School of Medicine in St. Louis have found that although it does not extend maximum lifespan in mice, activating a protein in muscle tissue increases average lifespan and prevents some age-related diseases. view more (2007-12-05)
Transplanting human gut bugs into mice helps understanding of metabolic system
Bugs found in the guts of humans, which play an important part in people's metabolic makeup, have been transplanted into mice to further understanding of the human and animal metabolic system. view more (2007-05-22)
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